H-InvDB x AHG DB
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H-InvDB_8.3 released on March 26, 2013.
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H-Invitational ID: HIT000336350 Accession number: BC100936 Created date: 26-Mar-2013 Last modified: 26-Mar-2013
Definition: Mitochondrial ornithine transporter 2.
 
 

Transcript original information
Accession number BC100936.1
CAGE tag ID NA
EST ID NA
Clone Number MGC:119152 IMAGE:40004046
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (SLC25A2) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (SLC25A2);
Sequence data provider NA
Annotation project NA
Length of cDNA 956[bp] (No. of exon:1)[A:230 T:246 G:263 C:217]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type PCR rescued clones
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0031997
Genomic location  G-integra Help Chromosome 5
Location 5q31.3
Position 140682477- 140683432
Strand -
Possible duplicated location(s) NA
Gene structure 1 exon(s)
Database links RefSeq NM_031947
Ensembl ENST00000239451
Entrez Gene Entrez Gene ID:83884
KEGG GENES KEGG GENES(83884)
GeneCard GeneCardSLC25A2*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000069782
Predicted CDS 1..906;  301[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.721
Database links RefSeq NP_114153
UniProt Q9BXI2
CCDS CCDS4258

Motif information
ORF

length(301),orf(1:906)
MKSGPGIQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDC
FLKTYAQVGLRGFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDK
QAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSH
NTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYELSRSFFAS
GRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFI
GTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMKQLEA
Y*
a.a.
length
InterPro Name
length(286), motif(4:289) 286 IPR001993 Mitochondrial substrate carrier [Family]
length(85), motif(7:91) 85 IPR018108 Mitochondrial substrate/solute carrier [Repeat]
length(294), motif(8:301) 294 IPR001993 Mitochondrial substrate carrier [Family]
length(85), motif(10:94) 85 IPR018108 Mitochondrial substrate/solute carrier [Repeat]
length(94), motif(104:197) 94 IPR018108 Mitochondrial substrate/solute carrier [Repeat]
length(93), motif(107:199) 93 IPR018108 Mitochondrial substrate/solute carrier [Repeat]
length(92), motif(206:297) 92 IPR018108 Mitochondrial substrate/solute carrier [Repeat]
length(87), motif(207:293) 87 IPR018108 Mitochondrial substrate/solute carrier [Repeat]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000336350
H-Inv cluster ID Locus viewHIX0031997
Accession number BC100936.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO; 
Coding potential  Help Protein coding; 
Definition Mitochondrial ornithine transporter 2.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_114153)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Experimental evidence Protein evidence
PubMed ID NA
Gene family/group Gene family H-Inv gene family/group ID HIF0000021
Gene family/group name Putative Mitochondrial substrate carrier (IPR001993).
Evidence motif (InterPro) ID IPR001993
Gene symbol/name HGNC symbol SLC25A2
HGNC aliases NA
HGNC name solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
DDBJ SLC25A2
UniProt NA
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000069782
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NM_031947
Ensembl ENST00000239451
Entrez Gene Entrez Gene ID:83884
KEGG GENES KEGG GENES(83884)
GeneCard GeneCardSLC25A2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Putative Mitochondrial substrate carrier (IPR001993). Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA

Gene ontology information
Molecular function binding (GO:0005488); 
Biological process transport (GO:0006810); 
Cellular component membrane (GO:0016020); 

Subcellular localization information  Last modified:26-Mar-2013
WoLF PSORT cytosol;  extracellular;  mitochondria;  plasma membrane;  Other; 
Target P Other
SOSUI membrane protein
TMHMM membrane protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:26-Mar-2013
Start End PDB_ID E-value Identity Coverage SCOP_ID
7 198 1okcA 1e-29 17.5 219/292 f.42.1.1
259 289 1okcA 1e-29 17.5 219/292 f.42.1.1
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:26-Mar-2013
Tissue-specific expression  H-ANGEL placenta/testis/ovary; 
Probe
information DNAProbeLocator
AceGene NA
Affymetrix
GeneChip
HG-Focus NA
HG-U133 224166_at; 
HG-U133A NA
HG-U133A_2 NA
HG-U133B 224166_at; 
HG-U133_Plus_2 224166_at; 
HG-U95 57269_at; 
HG-U95A NA
HG-U95B 57269_at; 
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2878632;  2878633; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 NA
Whole Human Genome Oligo Microarray:PGID247 NA
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:26-Mar-2013
Disease relation Disease name:NA
Related information in OMIM OMIM ID:NA Title:NA
Co-localized orphan diseases OMIM ID:  601888608850611091612554612571
Disease related mutation NA
Literature-Extracted GENe-Disease Associations (LEGENDA) LEGENDA Gene name Entrez Gene ID:(83884)
Disease Entrez Gene ID:(83884)
Substance Entrez Gene ID:(83884)
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo ViewerLEGENDALEGENDA

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
168 .. 168 T/C rs11952797 - CDS Synonymous[Ala56Ala]
191 .. 191 A/G rs115876844 - CDS Nonsynonymous[Tyr64Cys]
291 .. 291 A/G rs79139730 - CDS Synonymous[Gly97Gly]
440 .. 440 C/T rs34663948 + CDS Nonsynonymous[Ala147Val]
475 .. 475 G/T rs10075302 - CDS Nonsynonymous[Gly159Cys]
542 .. 542 T/G rs3749779 + CDS Nonsynonymous[Val181Gly]
676 .. 676 G/A/T rs3749780 + CDS
759 .. 759 C/T rs3749781 + CDS Synonymous[Leu253Leu]
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer