H-InvDB_9.0 released on May 27, 2015.
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H-Inv ID (HIT)
H-Inv cluster ID (HIX)
H-Inv protein ID (HIP)
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Definition*
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---
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H-Invitational ID:
HIT000331953
Accession number:
AY574901
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Mitogen-activated protein kinase kinase kinase 19; EC=2.7.11.1; Regulated in COPD, protein kinase; SPS1/STE20-related protein kinase YSK4;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Gene function information
H-Inv ID
HIT000331953
H-Inv cluster ID
HIX0002473
Accession number
AY574901.1
CAGE tag ID
NA
EST ID
NA
Transcript feature
Representative transcript;
Splicing isoform
Coding potential
Protein coding;
Definition
Mitogen-activated protein kinase kinase kinase 19; EC=2.7.11.1; Regulated in COPD, protein kinase; SPS1/STE20-related protein kinase YSK4;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
Q56UN5
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence
Protein evidence
PubMed ID
14702039
;
15489334
;
15815621
;
17344846
;
ALL
;
Gene family/group
H-Inv gene family/group ID
NA
Gene family/group name
NA
Evidence motif (InterPro) ID
NA
Gene symbol/name
HGNC symbol
MAP3K19
HGNC aliases
"Yeast Sps1/Ste20-related kinase 4 (S. cerevisiae)", "yeast Sps1/Ste20-related kinase 4 (S. cerevisiae)", "YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)"
HGNC name
mitogen-activated protein kinase kinase kinase 19
DDBJ
NA
UniProt
MAP3K19
EC number
EC 2.7.11.1
non-specific serine/threonine protein kinase;
GGDB
(GlycoGene Database)
Gene symbol
NA
Familly
NA
Designation
NA
Expression
NA
KEGG metabolic pathway
04150
:mTOR signaling pathway;
04210
:Apoptosis;
04310
:Wnt signaling pathway;
04320
:Dorso-ventral axis formation;
04340
:Hedgehog signaling pathway;
04350
:TGF-beta signaling pathway;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04530
:Tight junction;
04540
:Gap junction;
04620
:Toll-like receptor signaling pathway;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04664
:Fc epsilon RI signaling pathway;
04720
:Long-term potentiation;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04920
:Adipocytokine signaling pathway;
05010
:Alzheimer's disease;
05210
:Colorectal cancer;
Protein-protein interaction (PPI)
H-Inv protein ID
HIP000141753
No. of interaction
32
Interaction partner(s)
HIP000021472
;
HIP000024702
;
HIP000025861
;
HIP000027883
;
HIP000028292
;
HIP000034455
;
HIP000035228
;
HIP000036017
;
HIP000039154
;
HIP000042614
;
HIP000043732
;
HIP000045142
;
HIP000048130
;
HIP000048823
;
HIP000048828
;
HIP000068583
;
HIP000070754
;
HIP000075803
;
HIP000078552
;
HIP000085002
;
HIP000086388
;
HIP000089031
;
HIP000096529
;
HIP000097703
;
HIP000098093
;
HIP000103884
;
HIP000110949
;
HIP000144372
;
HIP000174663
;
HIP000199769
;
HIP000258753
;
HIP000354166
;
BIND
NA
DIP
NA
MINT
NA
HPRD
NA
IntAct
NA
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:80122
;
KEGG GENES
KEGG GENES(80122)
;
GeneCard
MAP3K19
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Human curated
Notes
NA
Related H-InvDB links
Gene family;
Similarity Search Tool
;
TACT
;
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome.
NA