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H-Invitational ID: HIT000297980 Accession number: CR618785 Created date: 26-Mar-2013 Last modified: 20-Apr-2012
Definition: WAS/WASL-interacting protein family member 1.
 
 

Transcript original information
Accession number CR618785.1
CAGE tag ID NA
EST ID NA
Clone Number CS0DD006YD05
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (WIPF1) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (WIPF1);
Sequence data provider NA
Annotation project NA
Length of cDNA 1987[bp] (No. of exon:8)[A:430 T:385 G:502 C:670]
Devision HTC
Molecular type mRNA
Library origin Cell type NA
Tissue type Neuroblastoma Cot 50-normalized
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0002607
Genomic location  G-integra Help Chromosome 2
Location 2q31.1
Position 175426932- 175547595
Strand -
Possible duplicated location(s) NA
Gene structure 8 exon(s)
Database links RefSeq NM_003387;  NM_001077269; 
Ensembl ENST00000272746;  ENST00000359761;  ENST00000392546;  ENST00000392547;  ENST00000392548;  ENST00000409415;  ENST00000409891;  ENST00000410117;  ENST00000436221;  ENST00000455428;  ENST00000467149;  ENST00000469002;  ENST00000470752;  ENST00000474332;  ENST00000480400;  ENST00000487291;  ENST00000488830;  ENST00000490887; 
Entrez Gene Entrez Gene ID:7456; 
KEGG GENES KEGG GENES(7456); 
GeneCard GeneCardWIPF1;  *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA-genome alignmentcDNA-genome alignment; 

Predicted CDS information
HIP ID HIP000087464
Predicted CDS 133..1644;  503[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.761
Database links RefSeq NP_001070737;  NP_003378; 
UniProt O43516; 
CCDS CCDS2260; 

Motif information
ORF

length(503),orf(133:1644) MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTV TNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRF PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEW ESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP IPR* 		a.a.
length		 InterPro Name
length(18), motif(32:49) 18 IPR003124 Actin-binding WH2 [Domain]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000297980
H-Inv cluster ID Locus viewHIX0002607
Accession number CR618785.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition WAS/WASL-interacting protein family member 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_003378)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Experimental evidence Protein evidence
PubMed ID NA
Gene family/group Gene family H-Inv gene family/group ID HIF0000034
Gene family/group name Putative Interferon-induced transmembrane protein (IPR007593).
Evidence motif (InterPro) ID IPR007593
Gene symbol/name HGNC symbol WIPF1
HGNC aliases "Wiskott-Aldrich syndrome protein interacting protein"
HGNC name WAS/WASL interacting protein family, member 1
DDBJ NA
UniProt NA
EC number NA
GGDB
(GlycoGene Database)
 Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000087464
No. of interaction 6
Interaction partner(s) HIP000039089;  HIP000082022;  HIP000082374;  HIP000099536;  HIP000100279;  HIP000109033; 
BIND NA
DIP 87916E; 
MINT NA
HPRD 01242;  04077;  07171;  09272;  17031; 
IntAct EBI-1184672;  EBI-2483335;  EBI-776423; 
Database links RefSeq NM_003387;  NM_001077269; 
Ensembl ENST00000272746;  ENST00000359761;  ENST00000392546;  ENST00000392547;  ENST00000392548;  ENST00000409415;  ENST00000409891;  ENST00000410117;  ENST00000436221;  ENST00000455428;  ENST00000467149;  ENST00000469002;  ENST00000470752;  ENST00000474332;  ENST00000480400;  ENST00000487291;  ENST00000488830;  ENST00000490887; 
Entrez Gene Entrez Gene ID:7456; 
KEGG GENES KEGG GENES(7456); 
GeneCard GeneCardWIPF1;  *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Curation status Auto-annotated
Notes NA
Related H-InvDB links Putative Interferon-induced transmembrane protein (IPR007593). Similarity Search ToolSimilarity Search Tool;  TACTTACT; 
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA


Subcellular localization information  Last modified:20-Apr-2012
WoLF PSORT nuclear;  cytosol; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Gene expression information  H-ANGEL DNAProbeLocator Last modified:20-Apr-2012
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator		 AceGene AGhsA240212; 
Affymetrix
GeneChip		 HG-Focus NA
HG-U133 202665_s_at; 
HG-U133A 202665_s_at; 
HG-U133A_2 202665_s_at; 
HG-U133B NA
HG-U133_Plus_2 202665_s_at; 
HG-U95 47755_at;  62743_at; 
HG-U95A NA
HG-U95B 47755_at; 
HG-U95C 62743_at; 
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2587851;  2587852;  2587853;  2587854;  2587858;  2587860;  2587866;  2587867;  2587868;  2587869;  2587871;  2587872;  2587873;  2587878;  2587879;  2587880;  2587924; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P251436;  A_23_P330612; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P330611;  A_23_P330616; 
Related H-InvDB links H-ANGELH-ANGEL;  DNAProbeLocatorDNAProbeLocator; 

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:20-Apr-2012
Disease relation Disease name:NA
Related information in OMIM OMIM ID:NA Title:NA
Co-localized orphan diseases OMIM ID:  600666;  607329;  609402; 
Disease related mutation NA
Literature-Extracted GENe-Disease Associations (LEGENDA) LEGENDA Gene name Entrez Gene ID:(7456)
Disease Entrez Gene ID:(7456)
Substance Entrez Gene ID:(7456)
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo Viewer;  LEGENDALEGENDA; 

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
66 .. 66 G/C rs113563347 - 5'UTR
174 .. 174 G/A rs111761533 - CDS Synonymous[Thr14Thr]
210 .. 210 T/C rs35923393 + CDS Synonymous[Asn26Asn]
402 .. 402 A/G rs114862098 - CDS Synonymous[Gly90Gly]
471 .. 471 C/G rs76308107 - CDS Synonymous[Ser113Ser]
725 .. 725 C/T rs4972450 - CDS Nonsynonymous[Pro198Leu]
782 .. 782 C/T rs11551322 + CDS Nonsynonymous[Pro217Leu]
1089 .. 1089 T/G rs112447307 - CDS Synonymous[Pro319Pro]
1279 .. 1279 C/T rs71417494 - CDS Nonsynonymous[Pro383Ser]
1282 .. 1282 C/T rs71417493 - CDS Nonsynonymous[Pro384Ser]
1296 .. 1296 C/T rs41270199 - CDS Synonymous[Asn388Asn]
1415 ^ 1416 -/T rs34236584 - CDS
1428 .. 1428 A/G rs76731102 - CDS Synonymous[Pro432Pro]
1445 .. 1445 G/A rs12052997 - CDS Nonsynonymous[Arg438Lys]
1546 .. 1546 A/G rs113179543 - CDS Nonsynonymous[Thr472Ala]
1578 .. 1578 C/T rs116757787 - CDS Synonymous[Asn482Asn]
1712 .. 1712 T/A rs113462357 - 3'UTR
1905 .. 1905 C/T rs115476647 - 3'UTR
1919 .. 1919 A/T rs41270197 - 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD); 
Related H-InvDB links VaryGeneVaryGene;  Repeat mask viewerRepeat Mask Viewer;