H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID:
HIT000195893
Accession number:
M59371
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Ephrin type-A receptor 2; EC=2.7.10.1; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; Precursor;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Transcript annotation summary
H-Inv ID
HIT000195893
H-Inv cluster ID
HIX0023618
H-Inv protein ID
HIP000048045
Accession number
M59371.1
CAGE tag ID
NA
EST ID
NA
Genomic location
Chromosome
1
Location
1p36.13
Position
16450833- 16482538
Strand
-
Transcript feature
NO;
Coding potential
Protein coding;
Definition
Ephrin type-A receptor 2; EC=2.7.10.1; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; Precursor;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P29317
) [Identity/coverage = 99.59%/100.0%] to Homo sapiens (Human). protein.
Gene family / group
NA
Gene symbol/name
HGNC symbol
EPHA2
HGNC aliases
"EphA2"
HGNC name
EPH receptor A2
DDBJ
ECK
UniProt
EPHA2
EC number
EC 2.7.10.1
receptor protein-tyrosine kinase;
KEGG metabolic pathway
04020
:Calcium signaling pathway;
04060
:Cytokine-cytokine receptor interaction;
04210
:Apoptosis;
04320
:Dorso-ventral axis formation;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04540
:Gap junction;
04640
:Hematopoietic cell lineage;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04930
:Type II diabetes mellitus;
05050
:Dentatorubropallidoluysian atrophy (DRPLA);
05120
:Epithelial cell signaling in Helicobacter pylori infection;
05210
:Colorectal cancer;
PubMed ID
2174105
;
9267020
;
10655584
;
11280802
;
12167657
;
12467573
;
15489334
;
16236711
;
16710414
;
17135240
;
17332925
;
17344846
;
18339848
;
18669648
;
18691976
;
18794797
;
19005574
;
19159218
;
19306328
;
19369195
;
19525919
;
19567782
;
19573808
;
19649315
;
20068231
;
20679435
;
20861311
;
21269460
;
22570727
;
ALL
;
Related H-InvDB links
Similarity Search Tool
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:1969
;
KEGG GENES
KEGG GENES(1969)
;
GeneCard
EPHA2
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Auto-annotated
Notes
NA