H-InvDB_8.3 released on March 26, 2013. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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H-Invitational ID: HIT000061459 Accession number: AB087802 Created date: 26-Mar-2013 Last modified: 20-Apr-2012 Definition: Uridine diphosphate glucose pyrophosphatase.

		Select format Flat file XML file Nucleotide sequence fasta Protein sequence fasta

Transcript original information Accession number AB087802.1 CAGE tag ID NA EST ID NA Clone Number NA Experimental resources   NBRC ; HGPD ; Antibody (NUDT14) ; Catalog (NUDT14); Sequence data provider NA Annotation project NA Length of cDNA 780[bp] (No. of exon:5)[A:160 T:144 G:245 C:231] Devision HUM Molecular type mRNA Library origin Cell type NA Tissue type Tyroid gland Develpmental stage NA

Sequence quality information CDS feature Complete CDS Kozak sequence NA PolyA Site: 751(+) Signal: 730-734(+) Vector/adapter sequence NA Frame shift NA Remaining intron NA Splice site acceptor (NAGNAG) NA Transcript quality feature NA Notes NA

ATGGAGCGCATCGAGGGGGCGTCCGTGGGCCGCTGCGCCGCCTCACCCTA CCTGCGGCCGCTCACGCTGCATTACCGCCAGAATGGTGCCCAGAAGTCCT GGGACTTCATGAAGACGCATGACAGCGTGACCGTTCTCTTATTCAACTCT TCTCGGAGGAGCCTGGTGTTGGTGAAGCAGTTCCGGCCAGCTGTGTATGC GGGTGAGGTGGAGCGCCGCTTCCCAGGGTCCCTAGCAGCTGTAGACCAGG ACGGGCCTCGGGAGCTACAGCCAGCCCTGCCCGGCTCAGCGGGGGTGACA GTTGAGCTGTGTGCCGGCCTCGTGGACCAGCCTGGGCTCTCGCTGGAGGA AGTGGCTTGCAAGGAGGCTTGGGAGGAGTGTGGCTACCACTTGGCCCCCT CTGATCTGCGCCGGGTCGCCACATACTGGTCTGGAGTGGGACTGACTGGC TCCAGACAGACCATGTTCTACACAGAGGTGACAGATGCCCAGCGTAGCGG TCCAGGTGGGGGCCTGGTGGAGGAGGGTGAGCTCATTGAGGTGGTGCACC TGCCCCTGGAAGGCGCCCAGGCCTTTGCAGACGACCCGGACATCCCCAAG ACCCTCGGCGTCATCTTTGGTGTCTCATGGTTCCTCAGCCAGGTGGCCCC CAACCTGGATCTCCAGTGAGACTCCAGGGTTCTAGACAGAGGCCAGTCTT GGCCACTCACCCCACACCCCGCGGACCCCAATAAAGGCTTGCATAGCTCC AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Gene structure information

H-Inv cluster ID		HIX0202090
Genomic location	Chromosome	14
	Location	NA
	Position	105639276- 105647546
	Strand	-
Possible duplicated location(s)		NA
Gene structure		5 exon(s)
Database links	RefSeq	NM_177533;
	Ensembl	ENST00000339418;  ENST00000392568;  ENST00000535832;
	Entrez Gene	Entrez Gene ID:256281;
	KEGG GENES	KEGG GENES(256281);
	GeneCard	NUDT14;  *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links		H-DBAS;  G-integra;  cDNA-genome alignment;

Predicted CDS information HIP ID HIP000049917 Predicted CDS 1..669;  222[aa];  Orientation:+1;  Codon Adaptation Index (CAI). 0.805 Database links RefSeq NP_803877;  UniProt O95848;  CCDS CCDS10000;

MERIEGASVGRCAASPYLRPLTLHYRQNGAQKSWDFMKTHDSVTVLLFNS SRRSLVLVKQFRPAVYAGEVERRFPGSLAAVDQDGPRELQPALPGSAGVT VELCAGLVDQPGLSLEEVACKEAWEECGYHLAPSDLRRVATYWSGVGLTG SRQTMFYTEVTDAQRSGPGGGLVEEGELIEVVHLPLEGAQAFADDPDIPK TLGVIFGVSWFLSQVAPNLDLQ*

Motif information

	a.a. length	InterPro	Name
	212	IPR004385	Nucleoside diphosphate pyrophosphatase [Family]
	218	IPR000086	NUDIX hydrolase domain [Domain]
	215	IPR015797	NUDIX hydrolase domain-like [Domain]
	162	IPR000086	NUDIX hydrolase domain [Domain]

Gene function information

H-Inv ID		HIT000061459
H-Inv cluster ID		HIX0202090
Accession number		AB087802.1
CAGE tag ID		NA
EST ID		NA
Transcript feature		NO;
Coding potential		Protein coding;
Definition		Uridine diphosphate glucose pyrophosphatase.
Similarity category		Category: Identical to known human protein(Category I).
		Identical to known human protein (NP_803877)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Experimental evidence		Protein evidence
PubMed ID		NA
Gene family/group	H-Inv gene family/group ID	NA
	Gene family/group name	NA
	Evidence motif (InterPro) ID	NA
Gene symbol/name	HGNC symbol	NUDT14
	HGNC aliases	NA
	HGNC name	nudix (nucleoside diphosphate linked moiety X)-type motif 14
	DDBJ	UGPP
	UniProt	NA
EC number		NA
GGDB (GlycoGene Database)	Gene symbol	NA
	Familly	NA
	Designation	NA
	Expression	NA
KEGG metabolic pathway		NA
Protein-protein interaction (PPI)	H-Inv protein ID	HIP000049917
	No. of interaction	NA
	Interaction partner(s)	NA
	BIND	NA
	DIP	NA
	MINT	NA
	HPRD	NA
	IntAct	NA
Database links	RefSeq	NM_177533;
	Ensembl	ENST00000339418;  ENST00000392568;  ENST00000535832;
	Entrez Gene	Entrez Gene ID:256281;
	KEGG GENES	KEGG GENES(256281);
	GeneCard	NUDT14;  *GeneCards is provided free to academic non-profit institutions.
	etc	Human-Gene diversity Of Life-style related Diseases;
Curation status		Auto-annotated
Notes		NA
Related H-InvDB links		Gene family;  Similarity Search Tool;  TACT;

fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome.

NA

Gene ontology information

Molecular function	metal ion binding (GO:0046872);  hydrolase activity (GO:0016787);  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);

Subcellular localization information

Last modified:20-Apr-2012

WoLF PSORT	cytosol;  nuclear;  extracellular;
Target P	Not predicted
SOSUI	soluble protein
TMHMM	soluble protein
PTS1	Not targeted
Related H-InvDB links	LIFEdb;  JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP)

Last modified:20-Apr-2012

Start End PDB_ID E-value Identity Coverage SCOP_ID 28 159 1v8iA 2e-11 29.5 95/150 d.113.1.1

Related H-InvDB links GTOP

Gene expression information

Last modified:20-Apr-2012

Tissue-specific expression			NA
Probe information	AceGene		NA
	Affymetrix GeneChip	HG-Focus	NA
		HG-U133	231910_at;  231914_at;
		HG-U133A	NA
		HG-U133A_2	NA
		HG-U133B	231910_at;  231914_at;
		HG-U133_Plus_2	231910_at;  231914_at;
		HG-U95	50425_at;
		HG-U95A	NA
		HG-U95B	50425_at;
		HG-U95C	NA
		HG-U95D	NA
		HG-U95E	NA
		HG-U95Av2	NA
		HuEx-1_0	3581486;  3581487;  3581488;  3581492;  3581494;  3581495;  3581497;  3581498;
		HuGeneFL	NA
	Agilent	Human 1A Oligo Microarray:PGID215	A_23_P414974;
		Whole Human Genome Oligo Microarray:PGID247	A_23_P414978;  A_32_P5976;
Related H-InvDB links			H-ANGEL;  DNAProbeLocator;

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Single Nucleotide Polymorphism (SNP) and indel  Location Variation dbSNP ID Strand CDS/UTR Translation 41 .. 41 C/T rs17095304 + CDS Nonsynonymous[Ala14Val] 282 .. 282 C/T rs117624322 - CDS Synonymous[Pro94Pro] 671 .. 671 A/G rs116285474 - 3'UTR 749 .. 749 C/T rs115869881 - 3'UTR  Microsatellite (Short Tandem Repeat, STR) No data available  Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD) No data available

Repeat  No data available Database links Human-Gene diversity Of Life-style related Diseases(H-GOLD);  Related H-InvDB links VaryGene;  Repeat Mask Viewer;