H-Inv ID |
HIT000038564 |
H-Inv cluster ID |
HIX0079174
|
H-Inv protein ID |
HIP000042851
|
Accession number |
BC019230.1
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
10 |
Location |
10p15.1
|
Position |
5136614-
5149877
|
Strand |
+
|
Transcript feature
|
NO;
|
Coding potential
|
Protein coding;
|
Definition |
Aldo-keto reductase family 1 member C3; EC=1.-.-.-; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; EC=1.1.1.213; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; EC=1.1.1.112; Prostaglandin F synthase; PGFS; EC=1.1.1.188; Testosterone 17-beta-dehydrogenase 5; EC=1.1.1.239; EC=1.1.1.64; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC=1.3.1.20; |
Similarity category
|
Category: Identical to known human protein(Category I).
|
Identical to known human protein (P42330)
[Identity/coverage = 100.0%/100.0%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
AKR1C3
|
HGNC aliases |
"hydroxysteroid (17-beta) dehydrogenase 5", "aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)"
|
HGNC name |
aldo-keto reductase family 1, member C3
|
DDBJ |
AKR1C3
|
UniProt |
AKR1C3
|
EC number |
EC 1.1.1.112indanol dehydrogenase;
EC 1.1.1.188prostaglandin-F synthase;
EC 1.1.1.2133alpha-hydroxysteroid dehydrogenase (A-specific);
EC 1.1.1.2393alpha(17beta)-hydroxysteroid dehydrogenase (NAD+);
EC 1.1.1.64testosterone 17beta-dehydrogenase (NADP+);
EC 1.3.1.20trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
|
KEGG metabolic pathway |
00150
:Androgen and estrogen metabolism;
00590
:Arachidonic acid metabolism;
00980
:Metabolism of xenobiotics by cytochrome P450;
|
PubMed ID |
7626489;
7650035;
7788527;
8274401;
9415401;
9927279;
10557352;
10622721;
10672042;
11165022;
14702039;
14979715;
14996743;
15087468;
15164054;
15489334;
21269460;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:8644;
|
KEGG GENES |
KEGG GENES(8644);
|
GeneCard |
AKR1C3;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Auto-annotated
|
Notes |
NA
|