H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000028234 Accession number: AL833322 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Similar to DNA annealing helicase and endonuclease ZRANB3; Annealing helicase 2; AH2; Zinc finger Ran-binding domain-containing protein 3; Includes: DNA annealing helicase ZRANB3; EC=3.6.4.-; Includes: Endonuclease ZRANB3; EC=3.1.-.-;
 
 

Transcript original information
Accession number AL833322.1
CAGE tag ID NA
EST ID NA
Clone Number DKFZp686D0128
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ZRANB3) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ZRANB3);
Sequence data provider Provider:DKFZ/MIPS
Annotation project H-Invitational FLcDNA
Length of cDNA 4151[bp] (No. of exon:22)[A:1363 T:1090 G:903 C:795]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type human testis
Develpmental stage adult
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA Site: 4132(+) Signal: 4110-4114(+)
Vector/adapter sequence NA
Frame shift 212-213[bp] Deletion(G);
Remaining intron NA
Splice site acceptor (NAGNAG) TAGGAG; 
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0002475
Genomic location  G-integra Help Chromosome 2
Location 2q21.3
Position 135957236- 136288182
Strand -
Possible duplicated location(s) NA
Gene structure 22 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:84083
KEGG GENES KEGG GENES(84083)
GeneCard GeneCardZRANB3*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000163819
Predicted CDS 123..1409;  428[aa];  Orientation:+3; 
Codon Adaptation Index (CAI). 0.706

Motif information
ORF

length(428),orf(123:1409)
MPRVHNIKKSLTPHISCVTNESDNLLDFLPDRLRAKLLPFQKDGIIFALK
RNGRCMVADEMGLGKTIQAIGITYFYKEEWPLLIVVPSSLRYPWTEEIEK
WIPELSPEEINVIQNKTDVRRMSTSKVTVLGYGLLTADAKTLIDALNNQN
FKVVIVDESHYMKSRNATRSRILLPIVQKARRAILLTGTPALGRPEELFM
QIEALFPQKFGRWTDYAKRYCNAHIRYFGKRPQWDCRGASNLNELHQLLS
DIMIRRLKTEVLTQLPPKVRQRIPFDLPSAAAKELNTSFEEWEKIMRTPN
SGAMETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSM
LQACTEAVIENKTRYIRIDGSVSSSERIHLVNQFQKDPDTRVAILSIQAA
GQDLYDKVAWGKRTLVSGLFMECFCFVP*
a.a.
length
InterPro Name
length(235), motif(22:256) 235 IPR027417 P-loop containing nucleoside triphosphate hydrolase [Domain]
length(184), motif(22:205) 184 IPR027417 P-loop containing nucleoside triphosphate hydrolase [Domain]
length(179), motif(33:211) 179 IPR014001 Helicase superfamily 1/2, ATP-binding domain [Domain]
length(163), motif(46:208) 163 IPR014001 Helicase superfamily 1/2, ATP-binding domain [Domain]
length(237), motif(51:287) 237 IPR000330 SNF2-related [Domain]
length(45), motif(146:190) 45 IPR027417 P-loop containing nucleoside triphosphate hydrolase [Domain]
length(17), motif(263:279) 17 IPR027417 P-loop containing nucleoside triphosphate hydrolase [Domain]
length(89), motif(313:401) 89 IPR027417 P-loop containing nucleoside triphosphate hydrolase [Domain]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000028234
H-Inv cluster ID Locus viewHIX0002475
Accession number AL833322.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Similar to DNA annealing helicase and endonuclease ZRANB3; Annealing helicase 2; AH2; Zinc finger Ran-binding domain-containing protein 3; Includes: DNA annealing helicase ZRANB3; EC=3.6.4.-; Includes: Endonuclease ZRANB3; EC=3.1.-.-;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q5FWF4)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 11230166147020391548933415815621179740051969033221078962227045582270537022759634ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ZRANB3
HGNC aliases NA
HGNC name zinc finger, RAN-binding domain containing 3
DDBJ NA
UniProt ZRANB3
EC number EC 3.1.-.-Acting on Ester Bonds;  EC 3.6.4.-Acting on acid anhydrides; involved in cellular and subcellular movement; 
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000163819
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:84083
KEGG GENES KEGG GENES(84083)
GeneCard GeneCardZRANB3*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA

Gene ontology information
Molecular function DNA binding (GO:0003677);  ATP binding (GO:0005524); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT cytosol;  mitochondria;  nuclear;  peroxisome; 
Target P Not predicted
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
171 197 2cr8A1 3e-05 29.6 27/41 g.41.11.1
288 394 1r4mB 1e-11 14.0 107/418 c.111.1.2
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene NA
Affymetrix
GeneChip
HG-Focus NA
HG-U133 239538_at; 
HG-U133A NA
HG-U133A_2 NA
HG-U133B 239538_at; 
HG-U133_Plus_2 239538_at; 
HG-U95 52836_at; 
HG-U95A NA
HG-U95B NA
HG-U95C 52836_at; 
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2577720;  2577721;  2577724;  2577725;  2577726;  2577727;  2577728;  2577730;  2577731;  2577732;  2577733;  2577734;  2577737;  2577738;  2577739;  2577746;  2577747;  2577748;  2577749;  2577750;  2577751;  2577752;  2577760;  2577761;  2577762;  2577766;  2577769;  2577770;  2577771;  2577788;  2577790;  2577791; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 NA
Whole Human Genome Oligo Microarray:PGID247 A_23_P412059;  A_24_P222997;  A_24_P32394;  A_24_P367623; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
122 .. 122 C/G rs201985537 - 5'UTR
157 .. 157 C/T rs201054972 - CDS Nonsynonymous[Thr12Ile]
171 .. 171 T/C rs201616507 - CDS Nonsynonymous[Cys17Arg]
323 .. 323 C/G rs181120539 - CDS Nonsynonymous[Ile67Met]
454 .. 454 A/G rs201847967 - CDS Nonsynonymous[Asn111Ser]
490 .. 490 C/T rs61744510 - CDS Nonsynonymous[Ser123Leu]
510 .. 510 C/G rs61744517 - CDS Nonsynonymous[Leu130Val]
557 .. 557 A/C rs58165671 - CDS Synonymous[Ala145Ala]
604 .. 604 A/G rs183525970 - CDS Nonsynonymous[Tyr161Cys]
680 .. 680 T/C rs199705117 - CDS Synonymous[Leu186Leu]
758 .. 758 A/T rs199835442 - CDS Nonsynonymous[Arg212Ser]
889 .. 889 G/A rs57517364 - CDS Nonsynonymous[Arg256Lys]
959 .. 959 A/C rs150597226 - CDS Synonymous[Ser279Ser]
1011 .. 1011 A/C rs139659263 + CDS Synonymous[Arg297Arg]
1033 .. 1033 T/C rs183638659 - CDS Nonsynonymous[Met304Thr]
1101 .. 1101 A/G rs201037135 - CDS Nonsynonymous[Lys327Glu]
1135 .. 1135 C/T rs61733463 - CDS Nonsynonymous[Ser338Leu]
1196 .. 1196 C/G rs192962553 - CDS Synonymous[Val358Val]
1209 .. 1209 A/G rs151301223 - CDS Nonsynonymous[Thr363Ala]
1355 .. 1355 G/A rs202000744 - CDS Synonymous[Gly411Gly]
1400 .. 1400 T/A rs114746085 - CDS Nonsynonymous[Phe426Leu]
1448 .. 1448 C/G rs200901805 - 3'UTR
1502 .. 1502 G/A rs138094198 - 3'UTR
1506 .. 1506 G/A rs146966998 - 3'UTR
1578 ^ 1579 -/T rs35934129 - 3'UTR
1586 ^ 1587 -/G rs34559870 - 3'UTR
1627 .. 1627 G/T rs185868777 - 3'UTR
1650 .. 1650 A/G rs200334482 - 3'UTR
1668 .. 1668 A/C rs202055620 - 3'UTR
1702 .. 1702 T/G rs143717767 - 3'UTR
1838 .. 1838 G/A rs935615 + 3'UTR
1854 .. 1854 G/A rs7608121 - 3'UTR
1887 .. 1887 C/A rs78851113 - 3'UTR
1898 .. 1898 G/T rs182848471 - 3'UTR
1908 .. 1908 T/G rs199511562 - 3'UTR
1972 .. 1972 C/T rs75794892 - 3'UTR
1986 .. 1986 C/T rs202027165 - 3'UTR
2016 .. 2016 T/C rs61732188 - 3'UTR
2018 .. 2018 C/T rs200823309 - 3'UTR
2019 .. 2019 G/A rs76333606 - 3'UTR
2030 .. 2030 G/A rs61732190 - 3'UTR
2054 .. 2054 G/T rs111240763 - 3'UTR
2068 .. 2068 C/T rs58917764 - 3'UTR
2127 .. 2127 A/T rs59900519 - 3'UTR
2153 .. 2153 A/G rs138802764 - 3'UTR
2193 .. 2193 A/G rs113847534 - 3'UTR
2234 .. 2234 G/T rs79518188 - 3'UTR
2354 .. 2354 C/T rs199659879 - 3'UTR
2392 .. 2392 A/G rs149740689 - 3'UTR
2421 .. 2421 T/C rs207462407 - 3'UTR
2447 .. 2447 C/T rs200511870 - 3'UTR
2476 .. 2476 A/G rs16831460 - 3'UTR
2533 .. 2533 A/G rs145206010 - 3'UTR
2580 .. 2580 T/A rs201666971 - 3'UTR
2591 .. 2591 T/G rs75070328 - 3'UTR
2597 .. 2597 A/C rs200457883 - 3'UTR
2706 .. 2706 C/A rs142253659 - 3'UTR
2747 .. 2747 A/G rs186820943 - 3'UTR
2847 .. 2847 G/A rs115961809 - 3'UTR
2854 .. 2854 A/G rs7578111 - 3'UTR
2877 .. 2877 A/G rs201249007 - 3'UTR
2913 .. 2913 G/A rs144033732 - 3'UTR
2958 .. 2958 G/A rs114791090 - 3'UTR
3001 .. 3001 G/A rs202125924 - 3'UTR
3017 .. 3017 C/T rs202133794 - 3'UTR
3026 .. 3026 T/A rs181667799 - 3'UTR
3130 .. 3130 C/T rs199874816 - 3'UTR
3337 .. 3337 C/G rs187035401 - 3'UTR
3543 .. 3543 G/A rs115728864 - 3'UTR
3666 .. 3666 G/T rs72980360 - 3'UTR
3735 .. 3735 T/C rs189847507 - 3'UTR
3850 .. 3850 G/A rs147287349 - 3'UTR
3912 .. 3912 C/G rs143920184 - 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer