H-InvDB x AHG DB
Transcript view
H-InvDB_9.0 released on May 27, 2015.
Search by for Advanced Search
Home Quick guide Navi BLAST Site map Download Contact us Help
H-Invitational ID: HIT000000190 Accession number: AB007942 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Putative tyrosine-protein phosphatase auxilin; EC=3.1.3.48; DnaJ homolog subfamily C member 6;
 
 

Transcript original information
Accession number AB007942.1
CAGE tag ID NA
EST ID NA
Clone Number HH0220
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ;
Sequence data provider Provider:KDRI
Annotation project H-Invitational FLcDNA
Length of cDNA 5747[bp] (No. of exon:19)[A:1720 T:1597 G:1199 C:1231]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type brain
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) CAGAAG;  CAGGAG; 
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0000672
Genomic location  G-integra Help Chromosome 1
Location 1p31.3
Position 65730437- 65881552
Strand +
Possible duplicated location(s) NA
Gene structure 19 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:9829
KEGG GENES KEGG GENES(9829)
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000066517
Predicted CDS 158..2899;  913[aa];  Orientation:+2; 
Codon Adaptation Index (CAI). 0.742
Database links RefSeq NP_055602
UniProt O75061
CCDS CCDS30739

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000000190
H-Inv cluster ID Locus viewHIX0000672
Accession number AB007942.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Putative tyrosine-protein phosphatase auxilin; EC=3.1.3.48; DnaJ homolog subfamily C member 6;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (O75061)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 945548414702039154893341671041418669648ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
DDBJ KIAA0473
UniProt DNAJC6
EC number EC 3.1.3.48protein-tyrosine-phosphatase; 
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway 04514 :Cell adhesion molecules (CAMs);  04520 :Adherens junction;  04630 :Jak-STAT signaling pathway;  04660 :T cell receptor signaling pathway;  04662 :B cell receptor signaling pathway;  04670 :Leukocyte transendothelial migration;  04910 :Insulin signaling pathway;  04920 :Adipocytokine signaling pathway;  04940 :Type I diabetes mellitus;  05120 :Epithelial cell signaling in Helicobacter pylori infection; 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000066517
No. of interaction 5
Interaction partner(s) HIP000025839HIP000080656HIP000099143HIP000101253HIP000107553
BIND NA
DIP NA
MINT NA
HPRD 00350;  06256; 
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:9829
KEGG GENES KEGG GENES(9829)
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA


Subcellular localization information  Last modified:27-May-2015
WoLF PSORT nuclear;  cytosol;  golgi apparatus;  mitochondria; 
Target P Other
SOSUI membrane protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
77 212 1mkpA 2e-11 11.2 134/144 c.45.1.1
224 365 1d5rA1 5e-29 28.3 127/133 b.7.1.1
816 913 1nz6A 3e-22 95.9 98/98 a.2.3.1
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL neural; 
Probe
information DNAProbeLocator
AceGene AGhsA111620; 
Affymetrix
GeneChip
HG-Focus NA
HG-U133 204720_s_at;  204721_s_at; 
HG-U133A 204720_s_at;  204721_s_at; 
HG-U133A_2 204720_s_at;  204721_s_at; 
HG-U133B NA
HG-U133_Plus_2 204720_s_at;  204721_s_at; 
HG-U95 36022_at; 
HG-U95A 36022_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2340357;  2340377;  2340378;  2340379;  2340381;  2340384;  2340385;  2340386;  2340387;  2340388;  2340389;  2340390;  2340391;  2340392;  2340393;  2340394;  2340395;  2340396;  2340398;  2340399;  2340401;  2340402;  2340403;  2340404;  2340405;  2340406;  2416808; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P95359; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P147479;  A_23_P95359; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
169 .. 169 T/C rs148507710 + CDS Synonymous[Ser4Ser]
202 .. 202 G/A rs146062011 + CDS Synonymous[Glu15Glu]
250 .. 250 G/A rs139946043 + CDS Synonymous[Gly31Gly]
278 .. 278 T/C rs74486665 + CDS Synonymous[Leu41Leu]
335 .. 335 A/G rs201998655 + CDS Nonsynonymous[Thr60Ala]
378 .. 378 T/C rs139164991 + CDS Nonsynonymous[Ile74Thr]
381 .. 381 T/C rs200535972 + CDS Nonsynonymous[Val75Ala]
383 .. 383 A/T rs61757223 + CDS Nonsynonymous[Met76Leu]
402 .. 402 A/G rs149898870 + CDS Nonsynonymous[Asn82Ser]
429 .. 429 T/C rs145720238 + CDS Nonsynonymous[Val91Ala]
499 .. 499 G/A rs148204207 + CDS Synonymous[Lys114Lys]
630 .. 630 A/G rs139223941 + CDS Nonsynonymous[Asn158Ser]
664 .. 664 G/A rs61753391 + CDS Synonymous[Ala169Ala]
686 .. 686 G/A rs186061249 + CDS Nonsynonymous[Ala177Thr]
731 .. 731 A/G rs149588872 + CDS Nonsynonymous[Ile192Val]
815 .. 815 G/A rs146050826 + CDS Nonsynonymous[Ala220Thr]
830 .. 830 C/T rs141833490 + CDS Nonsynonymous[Arg225Cys]
982 .. 982 A/G rs148454327 + CDS Synonymous[Lys275Lys]
1025 .. 1025 A/G rs200712827 + CDS Nonsynonymous[Ile290Val]
1027 .. 1027 C/A rs138750399 + CDS Synonymous[Ile290Ile]
1043 .. 1043 G/A rs144323705 + CDS Nonsynonymous[Val296Met]
1056 .. 1056 T/C rs201840876 + CDS Nonsynonymous[Met300Thr]
1099 .. 1099 G/A rs144924736 + CDS Synonymous[Lys314Lys]
1117 .. 1117 A/G rs145888008 + CDS Nonsynonymous[Ile320Met]
1168 .. 1168 A/G rs148145327 + CDS Synonymous[Leu337Leu]
1252 .. 1252 A/T rs61758427 + CDS Synonymous[Leu365Leu]
1300 .. 1300 C/T rs189783499 + CDS Synonymous[Tyr381Tyr]
1305 .. 1305 C/T rs138800944 + CDS Nonsynonymous[Thr383Ile]
1306 .. 1306 A/T rs142136708 + CDS Synonymous[Thr383Thr]
1317 .. 1317 A/G rs144003387 + CDS Nonsynonymous[Asn387Ser]
1336 .. 1336 T/C rs202109326 + CDS Synonymous[Ser393Ser]
1360 .. 1360 G/A rs148673423 + CDS Synonymous[Thr401Thr]
1379 .. 1379 G/A rs202225808 + CDS Nonsynonymous[Ala408Thr]
1417 .. 1417 C/T rs139447717 + CDS Synonymous[Tyr420Tyr]
1442 .. 1442 C/T rs78141380 + CDS Nonsynonymous[Leu429Phe]
1478 .. 1478 T/A rs145329294 + CDS Nonsynonymous[Cys441Ser]
1486 .. 1486 A/G rs4325172 + CDS Synonymous[Glu443Glu]
1492 .. 1492 C/T rs11208644 + CDS Synonymous[His445His]
1563 .. 1563 A/G rs191459935 + CDS Nonsynonymous[Asn469Ser]
1675 ^ 1676 -/A rs35203656 + CDS
1696 .. 1696 G/A rs7551930 + CDS Synonymous[Pro513Pro]
1701 .. 1701 C/T rs141779215 + CDS Nonsynonymous[Ala515Val]
1702 .. 1702 G/A rs201766287 + CDS Synonymous[Ala515Ala]
1709 .. 1709 C/G rs201900120 + CDS Nonsynonymous[Pro518Ala]
1803 .. 1803 A/C rs199937139 + CDS Nonsynonymous[His549Pro]
1839 .. 1839 G/A rs142833575 + CDS Nonsynonymous[Arg561His]
1842 .. 1842 G/A rs139509177 + CDS Nonsynonymous[Arg562His]
1854 .. 1854 C/A rs143545548 + CDS Nonsynonymous[Ser566Tyr]
1864 .. 1864 G/A rs148619941 + CDS Synonymous[Ala569Ala]
1881 .. 1881 T/C rs151128869 + CDS Nonsynonymous[Val575Ala]
1953 .. 1953 T/C rs201147617 + CDS Nonsynonymous[Phe599Ser]
1969 .. 1969 T/C rs12077111 + CDS Synonymous[Ser604Ser]
1996 .. 1996 C/A rs4582839 + CDS Synonymous[Pro613Pro]
2011 .. 2011 G/A rs185245369 + CDS Synonymous[Ser618Ser]
2015 .. 2015 A/G rs77046530 + CDS Nonsynonymous[Thr620Ala]
2030 .. 2030 A/G rs145175543 + CDS Nonsynonymous[Ser625Gly]
2034 .. 2034 C/T rs138338673 + CDS Nonsynonymous[Thr626Met]
2035 .. 2035 G/A rs138889333 + CDS Synonymous[Thr626Thr]
2051 .. 2051 C/G rs146975649 + CDS Nonsynonymous[Gln632Glu]
2063 .. 2063 T/G rs76373786 + CDS Nonsynonymous[Ser636Ala]
2090 .. 2090 C/T rs200921954 + CDS Nonsynonymous[Pro645Ser]
2137 .. 2137 C/T rs145501615 + CDS Synonymous[Thr660Thr]
2145 .. 2145 C/T rs143504255 + CDS Nonsynonymous[Ser663Leu]
2169 .. 2169 G/A rs4915691 + CDS Nonsynonymous[Ser671Asn]
2188 .. 2188 T/A rs144446177 + CDS Nonsynonymous[Asp677Glu]
2197 .. 2197 C/T rs190507629 + CDS Synonymous[Ala680Ala]
2198 .. 2198 G/A rs140156759 + CDS Nonsynonymous[Asp681Asn]
2204 .. 2204 G/A rs146842973 + CDS Nonsynonymous[Gly683Arg]
2240 .. 2240 A/T rs113143702 + CDS Nonsynonymous[Thr695Ser]
2268 .. 2268 T/C rs77014468 + CDS Nonsynonymous[Phe704Ser]
2296 .. 2296 G/A rs113490907 + CDS Synonymous[Ala713Ala]
2408 .. 2408 A/G rs147882056 + CDS Nonsynonymous[Asn751Asp]
2437 .. 2437 T/G rs61733018 + CDS Synonymous[Pro760Pro]
2449 .. 2449 C/T rs193114909 + CDS Synonymous[Asn764Asn]
2454 .. 2454 G/A rs201984806 + CDS Nonsynonymous[Arg766His]
2466 .. 2466 C/T rs200310838 + CDS Nonsynonymous[Ser770Leu]
2673 .. 2673 C/T rs200138922 + CDS Nonsynonymous[Thr839Met]
2683 .. 2683 C/T rs149097758 + CDS Synonymous[Thr842Thr]
2684 .. 2684 G/A rs201692861 + CDS Nonsynonymous[Val843Ile]
2701 .. 2701 G/T rs201708707 + CDS Nonsynonymous[Glu848Asp]
2824 .. 2824 C/T rs148209150 + CDS Synonymous[Tyr889Tyr]
2866 .. 2866 A/G rs137902143 + CDS Synonymous[Glu903Glu]
3073 .. 3073 C/T rs9436293 + 3'UTR
3289 .. 3289 G/C rs112072071 + 3'UTR
3306 .. 3306 T/C rs149809339 + 3'UTR
3443 .. 3443 G/A rs10493377 + 3'UTR
3453 .. 3453 T/C rs75507639 + 3'UTR
3504 .. 3504 C/T rs9436732 + 3'UTR
3522 .. 3522 C/A rs11543262 + 3'UTR
3628 .. 3628 C/T rs181060481 + 3'UTR
3675 .. 3675 T/A rs185073465 + 3'UTR
3679 .. 3679 A/C rs12093960 + 3'UTR
3868 .. 3868 T/A rs9436733 + 3'UTR
3977 .. 3977 T/G rs41296144 + 3'UTR
4045 .. 4045 T/G rs41311152 + 3'UTR
4076 .. 4076 C/T rs148516808 + 3'UTR
4129 .. 4129 G/A rs190914954 + 3'UTR
4416 .. 4416 G/C rs183100818 + 3'UTR
4436 .. 4436 T/C rs185929700 + 3'UTR
4439 .. 4439 G/A rs41301082 + 3'UTR
4521 .. 4521 T/A rs191722489 + 3'UTR
4594 .. 4594 G/T rs207460156 + 3'UTR
4604 .. 4604 A/G rs183344684 + 3'UTR
4658 .. 4658 T/C rs112287683 + 3'UTR
4734 .. 4734 T/C rs151028684 + 3'UTR
4797 .. 4797 A/G rs141114915 + 3'UTR
5030 .. 5030 G/A rs1801792 + 3'UTR
5216 .. 5216 T/C rs144839147 + 3'UTR
5305 .. 5305 C/T rs146737325 + 3'UTR
5306 .. 5306 G/A rs188404850 + 3'UTR
5329 ^ 5330 -/CA rs72296234 + 3'UTR
5356 ^ 5357 -/AC/ACAC rs68089849 + 3'UTR
5364 ^ 5365 -/CA rs56339051 + 3'UTR
5517 .. 5517 A/T rs191166121 + 3'UTR
5644 .. 5644 G/A rs140338181 + 3'UTR
5696 .. 5696 T/A rs150331689 + 3'UTR
5737 .. 5737 T/A rs137976121 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
Type Start End Strand
U2 5694 5747 +
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer