H-InvDB_8.3 released on March 26, 2013. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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Locus view Protein view G-integra DiseaseInfo Viewer H-ANGEL Evola PPI view Gene Family/Group Hyperlink MS

H-Invitational ID: HIT000000030 Accession number: AB002322 Created date: 26-Mar-2013 Last modified: 20-Apr-2012 Definition: Serine/arginine repetitive matrix protein 2; 300 kDa nuclear matrix antigen; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; SR-related nuclear matrix protein of 300 kDa; Ser/Arg-related nuclear matrix protein of 300 kDa; Splicing coactivator subunit SRm300; Tax-responsive enhancer element-binding protein 803; TaxREB803;

		Select format Flat file XML file Nucleotide sequence fasta Protein sequence fasta

Transcript original information Accession number AB002322.3 CAGE tag ID NA EST ID NA Clone Number ee08846s1 Experimental resources   NBRC ; HGPD ; Antibody (SRRM2) ; Catalog (SRRM2); Sequence data provider Provider:KDRI;  Annotation project H-Invitational FLcDNA Length of cDNA 9003[bp] (No. of exon:15)[A:2205 T:1766 G:2209 C:2823] Devision HUM Molecular type mRNA Library origin Cell type normal human aortic endothelial cells Tissue type NA Develpmental stage NA

Sequence quality information CDS feature Complete CDS Kozak sequence NA PolyA NA Vector/adapter sequence NA Frame shift NA Remaining intron NA Splice site acceptor (NAGNAG) CAGCAG;  CAGGAG;  TAGCAG;  Transcript quality feature NA Notes NA

CGCAGTTGGAGCCCGTTGCGGCCCCTGAGGAAGCGAGGAGGCGTCGGCGT CGGCTGAGGCGGGCGGACCGGCGAGGCGAGGCGGCGGCCCCAGGCCCGAG GGACTCGGGAGCTCGAGCAGCGGCGGCGGCAAGACCTCTCCCCCTCGGAG GCGGCGGGCGGAGGCGGCGGGAGCGGTGGTGCCCCCCCCGGGCACGGGGC CATGTACAACGGGATCGGGCTGCCGACGCCCCGGGGCAGCGGCACCAACG GCTACGTCCAGCGCAACCTGTCCCTGGTGCGGGGCCGCCGGGGTGAGCGG CCTGACTACAAGGGAGAGGAGGAACTGCGGCGCCTGGAGGCTGCCCTGGT GAAGCGGCCTAATCCTGACATCCTGGACCACGAGCGCAAGCGGCGCGTCG AGCTGCGATGCCTCGAGCTGGAGGAGATGATGGAAGAGCAGGGGTACGAG GAACAGCAAATTCAGGAAAAAGTGGCGACCTTTCGACTCATGTTGCTGGA GAAGGATGTGAACCCTGGGGGCAAGGAGGAGACCCCAGGGCAGAGGCCAG CGGTCACGGAGACTCACCAGTTGGCAGAATTAAATGAGAAGAAGAATGAA AGACTCCGTGCTGCCTTTGGCATCAGTGATTCTTACGTAGATGGCAGCTC TTTTGATCCTCAGCGTCGTGCCCGAGAAGCTAAACAACCAGCTCCTGAGC CTCCCAAACCTTACAGCCTTGTTCGGGAGTCTAGCAGTTCTCGCTCACCA ACCCCAAAGCAGAAGAAGAAGAAAAAGAAGAAAGATAGAGGACGCAGGTC AGAGAGCAGCTCTCCTCGACGGGAGAGAAAGAAAAGCTCAAAGAAGAAGA AGCACAGGTCAGAATCTGAGTCCAAGAAACGTAAGCATAGGTCTCCCACT CCAAAGAGCAAACGTAAATCTAAGGACAAAAAGCGAAAGCGGTCTCGAAG TACAACACCAGCCCCCAAGAGCCGCCGGGCCCACCGTTCAACTTCTGCTG ACTCTGCTTCCTCCTCCGATACTTCCCGCAGTCGGTCTCGAAGTGCTGCA GCTAAAACTCATACAACTGCCTTGGCTGGGCGAAGTCCTTCCCCTGCTTC AGGGCGACGCGGGGAGGGAGATGCGCCTTTCAGTGAACCAGGTACTACCA GCACACAACGGCCTAGTAGCCCGGAGACTGCTACGAAACAGCCTAGCAGC CCTTATGAAGACAAAGATAAAGACAAGAAGGAGAAATCTGCAACTCGACC TAGCCCCTCTCCGGAAAGGAGCAGCACAGGCCCAGAACCACCTGCTCCCA CTCCGCTCCTTGCTGAGCGACATGGCGGCTCCCCACAACCCCTTGCAACC ACCCCCTTAAGCCAGGAGCCAGTGAACCCCCCATCTGAGGCCTCTCCAAC TCGGGACCGTTCACCACCTAAGTCTCCCGAGAAACTTCCCCAGTCTTCTT CCTCAGAGAGCAGCCCACCATCCCCTCAACCTACCAAAGTTTCTCGGCAT GCCAGCTCTTCCCCAGAAAGTCCTAAACCTGCTCCAGCTCCAGGGTCCCA CCGAGAGATTTCTTCTTCTCCCACATCTAAGAATCGCTCACATGGCCGAG CAAAACGGGATAAATCACATTCTCATACCCCCTCCCGTAGGATGGGGAGG TCCCGTAGCCCTGCCACCGCTAAGAGAGGGCGATCTCGGTCTCGAACCCC TACCAAGAGAGGTCATTCTCGATCCCGATCTCCCCAGTGGCGTAGGTCCA GGTCTGCACAGAGGTGGGGAAGATCTAGAAGCCCCCAGCGACGTGGCCGC TCTAGGTCTCCTCAGCGACCAGGCTGGTCTAGGAGCAGAAATACCCAGAG AAGAGGCAGGTCTAGGTCAGCAAGGCGAGGGAGGTCCCACTCTAGATCCC CAGCCACTAGGGGTAGATCTCGTTCTAGAACACCAGCCCGCCGGGGCAGG TCCCGCTCTAGAACACCTGCCAGGCGGAGATCACGATCCAGAACTCCCAC CAGGCGTAGGTCTCGGTCTAGAACACCAGCCCGGAGGGGCAGGTCTCGGT CTAGAACACCTGCTAGGCGCAGATCTAGGACCCGATCACCAGTACGACGC AGGTCTCGTAGTAGATCACCAGCCAGGAGAAGTGGCAGGTCACGCTCTAG AACCCCAGCTAGACGTGGCCGCTCACGCTCCAGAACCCCAGCCAGACGTG GCCGCTCACGCTCTAGAACCCCAGCTAGACGCAGTGGTCGCTCACGCTCC AGAACACCAGCCAGGAGAGGGAGGTCTCGGTCTAGGACACCAAGACGAGG AAGATCCCGCAGTAGAAGCTTAGTTAGACGTGGAAGATCTCACTCTAGAA CACCTCAAAGAAGAGGCAGATCTGGCTCATCTTCAGAGCGGAAAAACAAA TCCAGAACATCTCAAAGAAGAAGCAGGTCCAATTCAAGCCCAGAAATGAA GAAATCTCGCATTTCTTCAAGGCGGAGCAGGTCTCTCTCTTCACCACGGT CCAAAGCAAAATCTCGCTTGTCTTTGAGGCGCAGCCTTTCAGGGTCTTCC CCATGCCCTAAGCAAAAGTCACAGACACCACCCAGGCGCAGTCGCTCTGG ATCCTCCCAAACTAAAGCTAAATCTAGAACGCCACCCAGACGCAGTCGCT CCAGTTCTTCTCCGCCACCTAAACAGAAATCTAAGACACCATCAAGACAA AGTCATTCCAGTTCATCTCCTCATCCTAAAGTGAAATCTGGAACACCACC GAGGCAAGGGTCCATAACAAGTCCCCAGGCCAATGAGCAATCTGTAACGC CACAGAGACGGAGCTGTTTTGAATCATCACCTGACCCTGAGTTGAAATCT AGGACCCCTTCTAGACATAGCTGCTCAGGGTCCTCTCCTCCTAGAGTGAA ATCTAGCACACCTCCCAGACAGAGCCCATCTAGGTCATCATCTCCACAAC CCAAAGTGAAGGCAATAATATCACCAAGACAAAGAAGCCATTCTGGCTCC TCTTCTCCAAGTCCTAGTAGGGTGACGTCGAGAACAACTCCACGGCGAAG CAGATCAGTATCTCCCTGCTCCAATGTGGAATCCAGATTGTTGCCAAGAT ACAGTCATTCTGGGTCCTCCTCACCAGATACCAAAGTGAAACCTGAAACA CCGCCAAGACAAAGTCACTCAGGGTCTATTTCACCATACCCCAAAGTAAA GGCCCAAACTCCACCGGGGCCAAGTCTTTCTGGATCAAAGTCACCATGTC CCCAAGAGAAGTCTAAAGACTCACTAGTTCAAAGTTGCCCTGGATCCCTC TCTCTCTGTGCAGGAGTAAAATCTAGCACACCACCAGGCGAGAGCTATTT TGGTGTCTCATCTCTGCAACTGAAAGGACAATCTCAAACTTCACCAGACC ACAGATCTGATACTTCAAGTCCAGAAGTGAGACAGAGTCATTCAGAATCA CCATCTCTGCAGAGCAAATCTCAAACATCACCTAAGGGAGGTCGGTCCAG GTCTTCATCTCCAGTCACTGAGCTGGCATCCAGATCTCCAATAAGACAAG ATAGAGGTGAGTTCTCAGCGAGTCCTATGTTGAAATCTGGAATGTCTCCT GAGCAGAGCAGGTTCCAGTCTGACTCTTCTTCATATCCTACAGTGGACTC GAATTCTCTCTTGGGGCAGAGTAGATTGGAGACTGCTGAATCAAAAGAGA AAATGGCCTTACCCCCTCAGGAGGATGCTACTGCATCACCTCCTAGACAG AAAGACAAATTTAGTCCCTTTCCAGTACAGGATAGGCCTGAGTCTTCACT GGTATTCAAAGACACACTTAGAACCCCGCCAAGAGAAAGAAGTGGTGCTG GGTCATCTCCAGAAACAAAAGAGCAAAATAGTGCATTGCCTACGTCAAGC CAAGATGAAGAGTTAATGGAGGTGGTAGAGAAGTCTGAAGAACCCGCAGG CCAAATCCTGTCTCATTTGTCTTCAGAACTTAAAGAAATGTCCACAAGTA ACTTTGAATCATCTCCTGAAGTAGAAGAAAGGCCTGCTGTGTCTTTGACT CTTGATCAGAGCCAGTCACAGGCTTCTTTGGAAGCAGTAGAAGTCCCTTC AATGGCCTCATCTTGGGGTGGGCCACATTTTTCTCCAGAACATAAAGAAC TGTCTAACTCCCCACTCAGGGAGAACAGCTTTGGATCACCTTTAGAATTT AGAAACTCAGGCCCACTTGGTACAGAAATGAATACTGGATTTTCTTCTGA GGTTAAAGAAGATTTGAATGGACCGTTTCTTAATCAGCTGGAAACAGATC CATCTCTAGACATGAAAGAACAATCGACAAGATCCTCTGGACACAGCAGT TCTGAGTTATCCCCAGATGCAGTGGAAAAGGCAGGGATGTCTTCAAATCA GAGCATCTCTTCACCTGTGCTTGATGCTGTACCCAGAACACCCTCGAGAG AAAGAAGTAGTTCTGCATCTTCTCCTGAAATGAAAGATGGTTTACCCAGA ACTCCATCAAGGAGAAGCAGGTCTGGGTCTTCTCCAGGACTTAGAGATGG GTCTGGGACTCCCTCGAGGCACAGCCTGTCTGGGTCCTCTCCTGGAATGA AAGATATACCTAGAACGCCATCTAGAGGGAGAAGCGAATGTGATTCTTCC CCAGAACCGAAAGCTTTGCCTCAGACTCCTAGGCCGAGGAGTCGTTCTCC ATCATCCCCAGAGCTCAACAACAAGTGTCTTACCCCCCAGAGAGAAAGAA GCGGGTCAGAATCATCAGTTGATCAGAAAACTGTGGCTCGGACTCCCCTG GGGCAGAGAAGTCGTTCGGGATCCTCTCAAGAACTTGATGTGAAACCCAG TGCATCCCCTCAGGAAAGAAGTGAGTCAGACTCTTCTCCAGATTCTAAAG CCAAGACACGAACCCCACTTCGGCAGAGGAGTCGGTCTGGATCATCTCCA GAGGTTGACAGCAAATCTCGACTATCCCCTCGGCGCAGTAGGTCTGGTTC CTCCCCTGAAGTGAAAGATAAGCCAAGAGCAGCACCCAGGGCACAGAGTG GTTCTGATTCCTCTCCTGAACCTAAAGCTCCAGCCCCTCGGGCCCTTCCC AGACGAAGCAGATCAGGTTCATCAAGCAAAGGCAGAGGCCCTTCTCCTGA AGGAAGCAGCAGTACCGAGTCCTCTCCTGAACATCCGCCCAAATCCAGAA CTGCTCGCAGAGGTTCCAGGTCATCACCAGAGCCCAAGACCAAGTCTCGT ACACCACCTCGACGTCGCAGCTCTCGATCATCTCCGGAGCTAACAAGGAA GGCCAGACTGTCCCGTAGAAGCCGCTCTGCCTCATCCTCACCAGAAACTC GCTCTAGAACTCCCCCAAGGCACCGGAGAAGTCCCTCAGTGTCTTCCCCG GAGCCAGCCGAAAAATCGAGGTCTTCACGCCGACGGCGCTCAGCTTCATC TCCACGCACTAAGACAACCTCAAGGAGAGGCCGCTCTCCTTCGCCAAAGC CTCGTGGACTCCAGAGGTCCCGTTCCCGCTCAAGGAGAGAGAAAACAAGA ACAACCCGACGTCGAGATAGGTCTGGATCTTCTCAGTCAACCTCTCGGCG AAGACAGCGGAGCCGGTCAAGGTCGCGGGTTACTCGGCGGCGGAGGGGAG GCTCTGGTTATCACTCAAGGTCACCTGCCCGGCAGGAAAGTTCCCGGACC TCCTCTCGACGCCGAAGAGGCCGCTCTCGGACACCCCCAACCAGTCGGAA GCGTTCTCGCTCACGCACATCACCAGCCCCGTGGAAACGCTCTAGATCTC GAGCCTCTCCAGCCACTCACCGGCGATCCAGGTCCAGAACCCCCCTGATA AGCCGACGTAGGTCCAGATCTCGAACTTCACCAGTCAGCCGGAGACGGTC AAGGTCCAGGACTTCAGTGACTCGACGAAGATCCCGGTCAAGAGCATCCC CAGTGAGCAGAAGGCGATCCAGATCCAGAACGCCACCAGTAACCCGCCGT CGTTCAAGGTCTAGAACGCCAACAACACGCCGCCGCTCCCGTTCTAGAAC TCCACCAGTGACTCGCAGAAGGTCCAGATCCAGGACTCCACCAGTAACCA GGAGGCGATCTCGAAGCAGAACTTCGCCTATCACTCGCAGAAGATCAAGA TCCAGAACATCTCCGGTCACCCGAAGGAGATCTCGATCTCGCACATCTCC AGTAACTCGAAGAAGGTCCCGCTCTCGAACCTCACCAGTGACACGCCGCC GCTCTAGGTCCCGGACACCTCCAGCTATTCGGCGCCGCTCTAGATCTCGA ACGCCACTGTTACCACGCAAACGTTCTCGAAGTCGCTCACCACTTGCTAT CCGCCGCCGCTCCAGATCCCGTACTCCACGAACAGCTCGGGGTAAACGGT CCTTAACAAGATCTCCTCCAGCCATCCGCAGGCGTTCTGCATCTGGAAGT AGTTCTGATCGTTCACGATCTGCTACTCCTCCAGCAACAAGAAATCATTC TGGTTCACGGACACCTCCAGTAGCACTCAACAGTTCCAGAATGAGCTGCT TCAGTCGTCCTAGCATGTCCCCAACACCTCTTGATCGCTGCAGATCACCT GGAATGCTTGAACCCCTTGGCAGCTCTAGAACACCCATGTCTGTCCTGCA GCAAGCCGGCGGCTCCATGATGGATGGTCCAGGTCCCCGAATACCTGACC ACCAGAGAACATCTGTGCCAGAAAATCATGCTCAGTCCAGGATTGCACTT GCCCTGACAGCTATCAGTCTTGGCACCGCTCGGCCTCCTCCGTCCATGTC TGCTGCTGGCCTTGCTGCAAGAATGTCCCAGGTTCCAGCCCCGGTGCCTC TCATGAGTCTCAGAACCGCACCAGCAGCCAACCTTGCCAGCAGGATTCCT GCAGCCTCTGCGGCAGCCATGAACCTAGCCAGCGCCAGGACACCTGCCAT TCCAACAGCAGTGAACCTGGCTGACTCTCGAACGCCAGCTGCAGCAGCGG CCATGAACTTGGCCAGCCCCAGAACAGCGGTGGCACCTTCGGCTGTGAAC CTGGCTGACCCTCGCACTCCCACAGCCCCAGCTGTGAACCTAGCAGGGGC CAGAACCCCAGCTGCCTTGGCAGCTCTGAGTCTCACAGGCTCTGGCACAC CACCAACTGCTGCAAACTATCCCTCCAGCTCCAGAACACCACAGGCTCCA GCCTCTGCAAACCTGGTGGGTCCTCGGTCTGCACATGCCACAGCTCCTGT GAATATTGCCGGCTCCAGAACCGCCGCAGCCTTGGCCCCCGCGAGCCTCA CCAGTGCTAGGATGGCTCCAGCATTGTCTGGTGCAAACCTCACCAGCCCC AGGGTGCCCCTTTCTGCCTACGAGCGTGTCAGTGGCAGAACCTCACCACC GCTCCTTGACCGAGCTAGGTCCAGAACACCACCGTCTGCCCCAAGCCAAT CTAGGATGACCTCTGAACGGGCTCCCTCCCCTTCCTCTAGAATGGGCCAG GCTCCTTCACAGTCTCTTCTCCCTCCAGCACAGGATCAGCCGAGGTCTCC TGTGCCTTCTGCTTTTTCAGACCAATCCCGTTGTTTGATTGCCCAGACCA CCCCTGTAGCAGGGTCTCAGTCCCTTTCCTCTGGGGCAGTGGCAACGACC ACGTCCTCTGCTGGTGATCACAATGGCATGCTCTCTGTCCCTGCCCCTGG GGTGCCCCACTCTGATGTGGGGGAGCCACCTGCCTCTACTGGGGCCCAGC AGCCTTCTGCATTAGCCGCCCTGCAGCCAGCAAAGGAGCGGCGGAGTTCC TCCTCGTCGTCGTCGTCCTCTAGCTCCTCCTCTTCTTCATCATCGTCGTC GTCGTCCTCCTCCTCCTCTGGCTCCAGTTCTAGTGACTCAGAGGGCTCTA GCCTTCCTGTGCAACCTGAGGTGGCACTGAAGAGGGTCCCCAGCCCCACC CCAGCCCCAAAGGAGGCTGTTCGAGAGGGACGTCCTCCGGAGCCAACCCC AGCCAAACGGAAGAGGCGCTCTAGCAGTTCCAGTTCCAGCTCCTCCTCTT CATCTTCCTCCTCCTCCTCCTCCTCCTCTTCTTCCTCCTCCTCTTCCTCT TCTTCTTCTTCCTCCTCATCTTCCTCCTCCTCGTCGTCTTCCTCCCCTTC CCCTGCTAAGCCTGGCCCTCAGGCCTTGCCCAAACCTGCAAGCCCCAAGA AGCCACCCCCTGGCGAGCGGAGGTCCCGCAGCCCCCGGAAGCCAATAGAC TCCCTCAGGGACTCTCGGTCCCTCAGCTACTCGCCTGTGGAGCGTCGCCG TCCCTCGCCCCAGCCCTCACCACGGGACCAGCAGAGCAGCAGCAGTGAGC GGGGTTCCCGGAGAGGCCAGCGTGGGGACAGCCGCTCCCCCAGCCACAAG CGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCTCCTCCAG GTCTCCATAAATTGTCTTTGGGGGATTCCACCACACCCAATGCTCTGGAG CCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGCCGTGGGAGGGTCCTTGT CTGCTCTCCTTTGAACCTTGGCAGCCCTTGGATGGAGGGCTCCCTTTCCC TCCCCTTTTTTTTTTCTTTGTTCCTGTGAAATGTTAATCTCCGTGAGTTC TTCCTGGTTCATGTGTTCTGGGGGGTTTGGGGTGGGAGGGAATGCAGATG GGAGTTGGGGGAGGGGAGGATACAGTTCAGGATACCCCAGCCTGGAGTCA GGGCCAGGGAGGCATGGCCCCACTTGTATCCAGAAGTTCCCAGGGGTGAT TGTGATGGTGGTTGGGACTGGAGGTTGTATAAGGTGTTCTTGGAAGGAAG GGGCAGGAGTTGGAATTAGTTGGTCCCTACTGTCCCCCATGAGGTTGTGA ACCCCTCCCCCCAACTTTTCATGTTTCTTAAAGGCATTTTGGTTTTTTAA AATCTGTACAGCAAGAGCAACTTTTTCTGTCAAATAAAAATGAGAAATGC AGG

Gene structure information

H-Inv cluster ID		HIX0012738
Genomic location	Chromosome	16
	Location	16p13.3
	Position	2802678- 2821411
	Strand	+
Possible duplicated location(s)		NA
Gene structure		15 exon(s)
Database links	RefSeq	NM_016333;
	Ensembl	ENST00000301740;  ENST00000382300;  ENST00000382301;  ENST00000396975;  ENST00000544933;
	Entrez Gene	Entrez Gene ID:23524;
	KEGG GENES	KEGG GENES(23524);
	GeneCard	SRRM2;  *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links		H-DBAS;  G-integra;  cDNA-genome alignment;

Predicted CDS information HIP ID HIP000134552 Predicted CDS 202..8460;  2752[aa];  Orientation:+1;  Codon Adaptation Index (CAI). 0.76

MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALV KRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLE KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSS FDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRS ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRS TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP TKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR TPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRG RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMK KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG SSQTKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYF GVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDS NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAG QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPS MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSE VKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDG SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPS ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRT PPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQ QAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMS AAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI PTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGA RTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPV NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPP LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR PSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR SP*

Motif information

	a.a. length	InterPro	Name
	45	IPR013170	mRNA splicing factor, Cwf21 [Domain]

Gene function information

H-Inv ID		HIT000000030
H-Inv cluster ID		HIX0012738
Accession number		AB002322.3
CAGE tag ID		NA
EST ID		NA
Transcript feature		NO;
Coding potential		Protein coding;
Definition		Serine/arginine repetitive matrix protein 2; 300 kDa nuclear matrix antigen; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; SR-related nuclear matrix protein of 300 kDa; Ser/Arg-related nuclear matrix protein of 300 kDa; Splicing coactivator subunit SRm300; Tax-responsive enhancer element-binding protein 803; TaxREB803;
Similarity category		Category: Identical to known human protein(Category I).
		Identical to known human protein (Q9UQ35)  [Identity/coverage = 98.874%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence		Protein evidence
PubMed ID		9205841;  9531537;  10668804;  11004489;  11991638;  15302935;  15489334;  15616553;  16083285;  16565220;  16964243;  17081983;  17287340;  17525332;  17924679;  18187866;  18220336;  18669648;  19007248;  19369195;  19413330;  19608861;  19690332;  19854871;  21269460;  ALL;
Gene family/group	H-Inv gene family/group ID	NA
	Gene family/group name	NA
	Evidence motif (InterPro) ID	NA
Gene symbol/name	HGNC symbol	SRRM2
	HGNC aliases	NA
	HGNC name	serine/arginine repetitive matrix 2
	DDBJ	KIAA0324
	UniProt	SRRM2
EC number		NA
GGDB (GlycoGene Database)	Gene symbol	NA
	Familly	NA
	Designation	NA
	Expression	NA
KEGG metabolic pathway		NA
Protein-protein interaction (PPI)	H-Inv protein ID	HIP000134552
	No. of interaction	16
	Interaction partner(s)	HIP000006280;  HIP000017241;  HIP000028618;  HIP000033272;  HIP000034631;  HIP000037399;  HIP000050194;  HIP000071164;  HIP000089031;  HIP000097016;  HIP000101685;  HIP000113997;  HIP000206539;  HIP000251926;  HIP000258529;  HIP000287963;
	BIND	182619;  24516;
	DIP	111843E;
	MINT	MINT-2860098;  MINT-51381;  MINT-7234186;  MINT-7234199;  MINT-7234217;  MINT-7234231;  MINT-7234245;  MINT-7234259;  MINT-7234276;  MINT-7234292;  MINT-7234308;  MINT-7234326;  MINT-7234341;
	HPRD	00253;  00449;  00574;  00774;  02900;  03714;  04482;  06784;
	IntAct	EBI-3451383;  EBI-2927718;  EBI-2927710;  EBI-3504327;  EBI-951898;  EBI-2927702;  EBI-2847091;  EBI-2866476;  EBI-2831397;  EBI-2695978;  EBI-2805759;  EBI-2696171;  EBI-1633268;  EBI-1633249;  EBI-2805752;  EBI-2797353;
Database links	RefSeq	NM_016333;
	Ensembl	ENST00000301740;  ENST00000382300;  ENST00000382301;  ENST00000396975;  ENST00000544933;
	Entrez Gene	Entrez Gene ID:23524;
	KEGG GENES	KEGG GENES(23524);
	GeneCard	SRRM2;  *GeneCards is provided free to academic non-profit institutions.
	etc	Human-Gene diversity Of Life-style related Diseases;
Curation status		Auto-annotated
Notes		NA
Related H-InvDB links		Gene family;  Similarity Search Tool;  TACT;

fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome.

NA

Subcellular localization information

Last modified:20-Apr-2012

WoLF PSORT	nuclear;
Target P	Other
SOSUI	soluble protein
TMHMM	soluble protein
PTS1	Not targeted
Related H-InvDB links	LIFEdb;  JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Gene expression information

Last modified:20-Apr-2012

Tissue-specific expression			NA
Probe information	AceGene		AGhsA151502;
	Affymetrix GeneChip	HG-Focus	208610_s_at;
		HG-U133	207435_s_at;  208610_s_at;
		HG-U133A	207435_s_at;  208610_s_at;
		HG-U133A_2	207435_s_at;  208610_s_at;
		HG-U133B	NA
		HG-U133_Plus_2	1554671_a_at;  207435_s_at;  208610_s_at;
		HG-U95	32761_at;  65441_at;  78525_at;  78527_g_at;
		HG-U95A	32761_at;
		HG-U95B	NA
		HG-U95C	65441_at;
		HG-U95D	NA
		HG-U95E	78525_at;  78527_g_at;
		HG-U95Av2	NA
		HuEx-1_0	3645254;  3645256;  3645257;  3645258;  3645260;  3645262;  3645265;  3645267;  3645269;  3645271;  3645275;  3645278;  3645279;  3645280;  3645281;  3645282;  3645283;  3645284;  3645285;  3645286;  3645287;  3645288;  3645289;  3645290;  3645291;  3645292;  3645293;  3645294;  3645295;  3645296;  3645297;  3645298;  3645302;  3645303;  3645304;  3645309;  3645310;  3645311;  3645312;  3645313;  3645314;  3677140;  3677142;  3677143;  3677144;  3677145;  3677146;  3677147;  3677148;  3677149;  3677151;  3677153;  3677155;  3677157;  3677159;  3677161;  3677165;
		HuGeneFL	X97301_at;
	Agilent	Human 1A Oligo Microarray:PGID215	A_23_P152381;  A_23_P323166;
		Whole Human Genome Oligo Microarray:PGID247	A_23_P323166;  A_24_P50988;
Related H-InvDB links			H-ANGEL;  DNAProbeLocator;

Disease/pathology information

Last modified:20-Apr-2012

Disease relation		Disease name:NA
Related information in OMIM		OMIM ID:NA Title:NA
Co-localized orphan diseases		OMIM ID:  156850;  605013;  605021;  606668;  607339;  608558;  608903;  610260;
Disease related mutation		NA
Literature-Extracted GENe-Disease Associations (LEGENDA)	Gene name	Entrez Gene ID:(23524)
	Disease	Entrez Gene ID:(23524)
	Substance	Entrez Gene ID:(23524)
Related H-InvDB links		DiseaseInfo Viewer;  LEGENDA;

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Single Nucleotide Polymorphism (SNP) and indel  Location Variation dbSNP ID Strand CDS/UTR Translation 7 .. 7 T/C rs2240146 - 5'UTR 234 .. 234 G/T rs111402916 + CDS Synonymous[Arg11Arg] 286 .. 286 C/T rs11551732 + CDS Nonsynonymous[Arg29Cys] 615 .. 615 C/G rs74706545 + CDS Synonymous[Ala138Ala] 997 .. 997 G/T rs112146559 + CDS Nonsynonymous[Ala266Ser] 1038 .. 1038 T/C rs113566023 + CDS Synonymous[Ser279Ser] 1132 .. 1132 A/G rs79975303 + CDS Nonsynonymous[Ser311Gly] 1192 .. 1192 C/T rs79168841 + CDS Nonsynonymous[Pro331Ser] 1335 .. 1335 A/C rs117890014 + CDS Synonymous[Pro378Pro] 1505 .. 1505 G/C rs114899013 + CDS Nonsynonymous[Ser435Thr] 1736 .. 1736 A/C rs75813313 + CDS Nonsynonymous[Gln512Pro] 2014 .. 2014 C/T rs115253860 + CDS Nonsynonymous[Arg605Trp] 2154 .. 2154 C/T rs79910471 + CDS Synonymous[Thr651Thr] 2246 .. 2246 G/A rs116990973 + CDS Nonsynonymous[Arg682His] 2289 .. 2289 A/G rs75499358 + CDS Synonymous[Thr696Thr] 2319 .. 2319 C/T rs2240142 - CDS Synonymous[Ser706Ser] 2351 .. 2351 C/A rs116499978 + CDS Nonsynonymous[Thr717Lys] 2497 .. 2497 C/T rs113244516 + CDS Nonsynonymous[Arg766Trp] 2562 .. 2562 G/A rs2240141 - CDS Synonymous[Lys787Lys] 2593 .. 2593 C/T rs111652485 + CDS Nonsynonymous[Arg798Cys] 2611 .. 2611 A/C rs2240140 - CDS Nonsynonymous[Thr804Pro] 2768 .. 2768 C/G rs12185191 + CDS Nonsynonymous[Thr856Arg] 2797 .. 2797 A/G rs113836515 + CDS Nonsynonymous[Thr866Ala] 2849 .. 2849 C/G rs17136053 + CDS Nonsynonymous[Ser883Cys] 2963 .. 2963 C/A rs77172395 + CDS Nonsynonymous[Ala921Glu] 3040 .. 3040 C/T rs34275340 - CDS Nonsynonymous[Pro947Ser] 3127 ^ 3128 -/G rs34156460 + CDS 3145 .. 3145 G/A rs77942674 + CDS Nonsynonymous[Glu982Lys] 3150 .. 3150 A/C rs77210367 + CDS Synonymous[Thr983Thr] 3308 .. 3308 G/C rs72768765 + CDS Nonsynonymous[Cys1036Ser] 3624 .. 3624 C/G rs72768766 + CDS Nonsynonymous[Asp1141Glu] 3649 .. 3649 T/C rs35402245 - CDS Nonsynonymous[Ser1150Pro] 3746 .. 3746 G/T rs117384853 + CDS Nonsynonymous[Arg1182Ile] 3809 .. 3809 A/T rs9921332 + CDS Nonsynonymous[Lys1203Ile] 3834 .. 3834 A/G rs3094775 - CDS Synonymous[Arg1211Arg] 4133 .. 4133 C/T rs75894599 + CDS Nonsynonymous[Ser1311Phe] 4345 .. 4345 A/G rs112339953 + CDS Nonsynonymous[Ser1382Gly] 4362 .. 4362 C/T rs78949014 + CDS Synonymous[Ser1387Ser] 4699 .. 4699 C/G rs113263000 + CDS Nonsynonymous[Pro1500Ala] 4883 .. 4883 C/T rs28591365 + CDS Nonsynonymous[Ser1561Phe] 4909 .. 4909 C/A rs3094773 - CDS Synonymous[Arg1570Arg] 5318 .. 5318 G/A rs79121344 + CDS Nonsynonymous[Arg1706Lys] 5456 .. 5456 G/C rs114848780 + CDS Nonsynonymous[Arg1752Pro] 5857 .. 5857 C/T rs77226128 + CDS Nonsynonymous[Arg1886Cys] 6185 .. 6185 G/A rs111312335 + CDS Nonsynonymous[Arg1995Gln] 6299 .. 6299 G/C rs117133016 + CDS Nonsynonymous[Arg2033Pro] 6415 .. 6415 C/T rs34563620 - CDS Nonsynonymous[Pro2072Ser] 6557 .. 6557 G/A rs115704251 + CDS Nonsynonymous[Arg2119His] 6792 .. 6792 G/A rs118057303 + CDS Synonymous[Pro2197Pro] 6810 .. 6810 C/T rs61747729 + CDS Synonymous[Gly2203Gly] 6954 .. 6954 A/G rs111703345 + CDS Synonymous[Pro2251Pro] 7171 .. 7171 C/T rs61747731 + CDS Nonsynonymous[Pro2324Ser] 7522 .. 7522 C/T rs61747730 + CDS Nonsynonymous[Pro2441Ser] 7759 .. 7759 G/A rs112321557 + CDS Nonsynonymous[Ala2520Thr] 7769 .. 7769 C/G rs117824484 + CDS Nonsynonymous[Ala2523Gly] 7833 .. 7833 T/C rs2301802 - CDS Synonymous[Ser2544Ser] 7842 .. 7842 A/G rs114814069 + CDS Synonymous[Ser2547Ser] 7848 .. 7848 G/A rs117364218 + CDS Synonymous[Ser2549Ser] 7857 .. 7857 C/G rs59593256 + CDS Synonymous[Ser2552Ser] 7988 .. 7988 C/T rs111694508 + CDS Nonsynonymous[Pro2596Leu] 8115 .. 8115 C/T rs79439891 + CDS Synonymous[Ser2638Ser] 8299 .. 8299 C/T rs116681042 + CDS Nonsynonymous[Arg2700Cys] 8316 .. 8316 C/G rs35899615 + CDS Synonymous[Pro2705Pro] 8474 .. 8474 G/T rs1050134 + 3'UTR 8615 .. 8615 T/C rs78617860 + 3'UTR 8616 .. 8616 C/T rs11551731 - 3'UTR 8692 .. 8692 A/G rs111748580 + 3'UTR 8707 .. 8707 G/T rs75586278 + 3'UTR 8745 .. 8745 G/C rs112074102 + 3'UTR 8843 .. 8843 G/A rs8843 + 3'UTR 8927 .. 8927 C/T rs1050195 + 3'UTR 8974 .. 8974 T/C rs116928678 + 3'UTR  Microsatellite (Short Tandem Repeat, STR) Location Variation Strand 8056..8076 (tcc)7 +  Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD) No data available

Repeat  Type Start End Strand MIRb 570 654 + Database links Human-Gene diversity Of Life-style related Diseases(H-GOLD);  Related H-InvDB links VaryGene;  Repeat Mask Viewer;