H-InvDB_8.3 released on March 26, 2013. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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Locus view Protein view G-integra DiseaseInfo Viewer H-ANGEL Evola PPI view Gene Family/Group Hyperlink MS

H-Invitational ID: HIT000000003 Accession number: AB002294 Created date: 26-Mar-2013 Last modified: 20-Apr-2012 Definition: Similar to Uncharacterized protein; Fragment;

		Select format Flat file XML file Nucleotide sequence fasta Protein sequence fasta

Transcript original information Accession number AB002294.1 CAGE tag ID NA EST ID NA Clone Number HF0260 Experimental resources   NBRC ; HGPD ; Antibody (ZNF646) ; Catalog (ZNF646); Sequence data provider Provider:KDRI;  Annotation project H-Invitational FLcDNA Length of cDNA 7604[bp] (No. of exon:1)[A:1670 T:1378 G:2261 C:2295] Devision HUM Molecular type mRNA Library origin Cell type NA Tissue type brain Develpmental stage NA

Sequence quality information CDS feature Complete CDS Kozak sequence NA PolyA NA Vector/adapter sequence NA Frame shift NA Remaining intron NA Splice site acceptor (NAGNAG) NA Transcript quality feature NA Notes NA

GAGCAGATTCCTACTGTTCTTAAAGGACAGTAATGCCTTTTGAGTCTGGT CTGAAGAACATAACAGGTCTGTGATCAGAAGTAGGTTGCATCTCTCTCAA CTTTAATTTCCTTAGCTATACCTGTAGGGATGACTTAAGCCTAGGGGAGC TCCTATATTTGGGAAGCTTGTGCACAGGGAAGCCTTAAATGATGGTGCCT GCAGATTGGATCTAGTAGAAATTAGGTCCTTGGGCATGGATGCTTGGGGA ACCTCTCAGTGACCTCAGGTGAACTTGTTGCTCGTAGAGCCAAGAGGCGA AGTTAATTCAGGCCTTCCTTTTGACCACTGCCCCCTCTTCCTAGGCCTTG GCCCCTCCACCAGAGGAAGGTGCTGCCACGTGTCTGCTCCTTCTGAACCT CCAGGTTTCTGCTACGTTGCCCCATGGAGGACACACCCCCCTCACTCAGC TGCTCCGACTGTCAGCGCCACTTTCCCAGCCTCCCAGAGCTCTCTCGGCA CCGAGAACTGCTCCATCCATCTCCCAACCAGGACAGTGAGGAGGCTGACA GCATCCCTCGGCCCTACCGTTGTCAGCAGTGTGGGCGGGGCTACCGTCAC CCCGGGAGCCTGGTTAACCATCGTCGGACCCACGAGACTGGCCTTTTCCC CTGTACCACCTGTGGCAAGGACTTCTCCAATCCCATGGCTCTCAAGAGCC ATATGAGGACACATGCTCCTGAGGGCCGCCGCAGGCACAGGCCCCCACGC CCCAAGGAAGCCACTCCACACCTCCAGGGTGAGACGGTGTCCACTGACTC CTGGGGCCAAAGGCTTGGCTCTAGTGAAGGCTGGGAAAACCAGACAAAAC ATACAGAAGAGACACCTGACTGTGAATCTGTACCTGACCCCAGGGCAGCT TCGGGTACGTGGGAAGATCTGCCCACCAGACAAAGAGAAGGCTTGGCAAG CCACCCAGGTCCTGAGGATGGTGCAGACGGCTGGGGACCCTCCACTAACT CTGCCAGAGCCCCTCCTCTCCCCATCCCAGCCAGCAGCCTTCTTAGCAAC TTGGAACAGTATCTGGCTGAATCAGTAGTGAACTTCACAGGGGGCCAGGA GCCCACCCAGTCCCCTCCTGCTGAGGAGGAGCGGCGGTACAAATGTAGTC AGTGTGGCAAGACCTACAAGCACGCCGGGAGCCTCACCAACCACCGCCAG AGCCACACGCTGGGCATCTACCCCTGTGCCATCTGTTTCAAGGAGTTCTC TAACCTCATGGCTCTGAAGAACCACTCTCGACTGCATGCCCAGTATCGGC CTTACCACTGTCCCCACTGCCCCCGTGTCTTCCGGCTCCCCCGGGAGCTG CTGGAACACCAGCAGTCCCATGAGGGTGAAAGGCAGGAGCCACGCTGGGA GGAGAAAGGGATGCCCACCACCAATGGGCACACAGATGAGAGCAGCCAGG ACCAGCTCCCCAGTGCACAGATGCTGAATGGCTCTGCGGAGCTCAGCACC TCTGGGGAGCTGGAGGACAGTGGCCTGGAGGAATACCGGCCTTTCCGCTG TGGGGACTGTGGCCGTACTTACCGCCATGCTGGGAGCCTCATCAACCATC GAAAGAGCCACCAGACAGGTGTCTACCCCTGCTCACTCTGTTCTAAGCAG CTGTTCAATGCGGCTGCCCTCAAAAACCATGTGCGGGCTCATCACAGGCC CAGGCAAGGAGTTGGGGAAAATGGGCAGCCATCAGTCCCACCAGCTCCCC TGCTGCTGGCTGAGACCACCCACAAAGAGGAAGAGGACCCCACCACCACC CTGGACCATCGGCCCTATAAGTGCAGTGAGTGTGGTCGTGCTTACCGCCA CCGGGGGAGCCTGGTGAACCATCGCCACAGCCATCGGACTGGAGAGTACC AGTGCTCACTCTGTCCCCGCAAGTACCCCAATCTCATGGCCCTGCGCAAC CACGTGCGGGTACATTGCAAGGCTGCTCGCCGAAGTGCAGACATCGGGGC TGAGGGTGCCCCCAGCCACCTCAAGGTAGAACTCCCGCCTGACCCAGTGG AGGCAGAGGCAGCCCCGCACACAGATCAGGACCATGTGTGCAAACATGAA GAAGAGGCCACGGACATCACCCCAGCAGCAGACAAGACAGCAGCACATAT CTGTAGCATCTGTGGGCTGCTCTTTGAAGACGCTGAGAGCCTTGAACGTC ATGGCCTGACTCATGGGGCAGGGGAAAAGGAAAATAGCAGAACAGAGACC ACAATGTCACCTCCTAGGGCCTTTGCCTGCCGAGACTGTGGAAAGAGCTA TCGCCACTCAGGCAGCCTTATCAACCACAGGCAGACCCACCAGACAGGAG ACTTCAGTTGTGGGGCCTGTGCCAAGCACTTCCACACCATGGCTGCCATG AAGAACCACTTGCGCCGGCACAGTCGGCGGCGGAGCAGGCGGCATCGGAA GCGGGCTGGCGGTGCCAGCGGTGGGAGAGAAGCCAAACTCCTGGCAGCGG AGAGCTGGACCCGGGAGCTAGAAGACAATGAAGGCCTGGAGTCTCCCCAA GACCCTTCAGGGGAAAGTCCTCATGGGGCTGAAGGCAACCTGGAAAGTGA TGGGGACTGTTTGCAGGCTGAATCTGAAGGGGACAAATGTGGGCTTGAGA GGGATGAGACCCATTTCCAGGGTGATAAAGAGAGCGGAGGCACTGGGGAA GGACTGGAAAGGAAGGATGCCAGTTTACTTGACAACTTGGACATCCCAGG TGAGGAAGGTGGTGGCACTCACTTCTGCGATAGCCTCACTGGGGTGGATG AAGACCAGAAGCCAGCCACTGGCCAACCCAACTCCTCTTCCCACTCTGCC AATGCTGTCACTGGCTGGCAGGCTGGGGCCGCTCACACATGCTCTGACTG TGGGCATTCTTTCCCCCATGCCACTGGCCTGCTGAGCCACAGGCCCTGCC ACCCACCAGGCATCTATCAGTGCTCCCTCTGCCCGAAGGAGTTTGACTCT CTGCCTGCCCTCCGCAGCCACTTCCAGAACCATAGGCCTGGGGAGGCGAC CTCAGCACAGCCTTTCCTCTGCTGCCTCTGTGGCATGATCTTCCCTGGGC GGGCTGGCTACAGGCTTCACCGGCGCCAGGCCCACAGCTCCTCTGGCATG ACTGAGGGCTCAGAGGAGGAGGGGGAAGAGGAAGGAGTGGCAGAGGCAGC CCCTGCACGCAGTCCACCACTGCAGCTCTCGGAAGCAGAGCTGCTGAATC AGCTGCAGCGGGAGGTGGAAGCGCTGGACAGTGCAGGGTATGGGCACATC TGTGGCTGCTGTGGTCAGACCTACGATGACCTGGGGAGCCTGGAGCGTCA CCACCAAAGTCAGAGTTCTGGGACTACTGCAGACAAGGCTCCCAGCCCCT TGGGAGTGGCAGGTGATGCCATGGAGATGGTCGTGGACAGTGTCTTGGAG GACATAGTGAATTCTGTCTCTGGAGAGGGTGGAGATGCCAAGTCTCAAGA GGGAGCAGGCACCCCCTTGGGAGACAGCCTCTGCATCCAGGGTGGGGAAA GTTTGTTGGAGGCTCAGCCCCGCCCCTTCCGCTGCAACCAGTGTGGCAAG ACCTATCGCCATGGGGGCAGCCTGGTGAACCACCGCAAGATCCACCAGAC TGGAGACTTTCTCTGCCCTGTCTGCTCCCGCTGCTACCCCAACCTGGCTG CCTACCGTAATCATCTGCGGAACCACCCTCGCTGCAAAGGCTCTGAGCCC CAGGTTGGGCCCATCCCAGAGGCAGCAGGTAGCAGTGAGCTGCAGGTTGG GCCCATCCCAGAAGGAGGCAGCAACAAGCCCCAGCACATGGCAGAGGAGG GGCCGGGGCAAGCAGAAGTCGAGAAGCTCCAGGAAGAACTTAAAGTGGAG CCCCTGGAGGAAGTGGCCAGGGTGAAAGAAGAGGTGTGGGAGGAGACCAC TGTGAAGGGGGAGGAGATAGAGCCCAGGCTGGAGACTGCCGAGAAGGGCT GCCAGACTGAAGCCAGCTCTGAGCGGCCCTTCAGCTGCGAGGTGTGTGGC CGATCCTACAAGCACGCCGGCAGCCTCATCAACCACCGGCAGAGCCACCA GACCGGCCACTTTGGCTGTCAGGCCTGCTCCAAGGGCTTCTCAAACCTCA TGTCCCTCAAGAACCACCGGCGCATCCATGCAGATCCCCGACGTTTCCGC TGCAGCGAGTGTGGGAAGGCCTTCCGCCTGCGGAAACAGCTGGCCAGCCA CCAGCGGGTCCACATGGAACGGCGTGGGGGTGGGGGCACCCGAAAGGCGA CTCGGGAAGATCGGCCCTTCCGCTGTGGGCAGTGCGGGCGGACCTATCGC CACGCCGGCAGCCTCCTGAACCACCGGCGCAGCCACGAGACGGGCCAGTA CAGCTGCCCCACCTGCCCCAAGACCTACTCCAACCGCATGGCCCTGAAGG ACCACCAGAGGCTGCACTCAGAGAATCGGCGGCGACGGGCTGGACGGTCC AGGCGCACAGCTGTGCGTTGCGCCCTCTGTGGCCGCAGCTTCCCTGGCCG GGGATCTTTGGAGCGGCACCTGCGGGAGCATGAGGAGACAGAAAGGGAGC CAGCCAATGGCCAGGGAGGCCTGGATGGCACAGCGGCCAGTGAGGCGAAC CTGACTGGCAGCCAGGGACTAGAGACCCAATTGGGTGGTGCTGAGCCAGT ACCCCACTTGGAGGATGGAGTCCCAAGGCCAGGGGAGCGCAGTCAGAGCC CCATCAGGGCAGCAAGCTCAGAAGCCCCAGAGCCACTGTCCTGGGGTGCA GGGAAGGCAGGTGGGTGGCCGGTAGGTGGGGGACTGGGGAATCATAGTGG AGGCTGGGTTCCTCAGTTCCTAACTAGGTCAGAGGAGCCAGAGGACAGTG TCCACAGGAGTCCTTGCCACGCTGGTGACTGCCAGCTCAATGGACCTACT CTGAGTCACATGGATAGCTGGGACAACAGAGACAACAGCTCTCAGCTGCA GCCAGGGAGCCACTCCTCTTGCAGCCAGTGTGGCAAGACTTACTGCCAGT CAGGCAGCCTCTTGAACCACAACACCAACAAGACAGACCGACACTATTGC CTGCTCTGCTCCAAGGAGTTCTTAAATCCTGTGGCCACAAAGAGCCACAG CCACAACCACATAGACGCCCAGACCTTTGCCTGTCCTGACTGTGGCAAAG CCTTTGAGTCCCACCAGGAACTGGCCAGCCACCTGCAGGCTCATGCCCGG GGCCACAGCCAGGTGCCAGCCCAGATGGAGGAGGCCAGAGATCCCAAAGC CGGGACTGGGGAGGACCAGGTGGTTCTCCCTGGTCAAGGGAAAGCCCAGG AGGCCCCATCAGAAACCCCCAGAGGCCCAGGAGAGAGTGTGGAGAGAGCC AGGGGAGGACAAGCGGTGACGTCCATGGCGGCTGAGGACAAGGAGCGGCC CTTCCGCTGCACCCAGTGCGGGCGCTCCTACCGCCATGCTGGCAGCCTGC TGAACCACCAGAAGGCCCACACCACAGGGTTGTACCCGTGCTCCCTCTGT CCCAAACTTCTCCCTAACCTGCTGTCTCTTAAGAACCACAGCAGGACCCA CACGGACCCCAAGCGCCACTGCTGCAGCATCTGTGGCAAGGCCTTTCGGA CAGCTGCCCGGCTGGAGGGCCACGGGCGGGTCCATGCACCCCGGGAGGGG CCTTTCACCTGCCCCCATTGTCCCCGCCACTTCCGCCGCCGAATCAGCTT CGTGCAGCACCAGCAGCAGCACCAGGAGGAGTGGACGGTGGCCGGCTCCG GTAGGGGGCATGAAGGGTCCCAGGAGGAGGTGGGCACACAGTGGAGGGGG AAGTCCAGCCCCAAAGTCGGTGGGGGAGCAAGGAGTGAGAGGAGAGAGCC CCGGGGATTCTAAGAGGTGGGTGGGGGCTTGGCTATGGGGTGAGAGAAGT AGCTTGAGGATGTGCTGAGCTGAGCACCCGCAAGTCAGGTATAACAAATA GCAGGGTGGGTTGGGCAGCACGTGGGGGCGTGGTCAGGCCGAGGCTGCTA CCTGGGCTCCTCCATTACACTGTAGCCAGAATGGAATGGTCTTTCTGTTC AGGGGAAGGTCACTGGGTACCCCCTGGCTGCTGTGTCTGGAAACCCTCCT GAGTCAGCCAGTAAAGTAATGACTTCCAGAGAAAAAGAGGAAGCCATTGG TTTGGTCTAGGTTCCATTCTTTCCTGGAGCAGGCCGGGTGCCAGGGAACA AGGGATGGGGCATGGGCTCCACGGCTTCCCTGCTGACTTGGCCACGGAAA CTGGTTCACTGGTTGGCACCCTACTCCCTGTCCCTCTTTCCCTGCGCCTT GTCTCTGCTGCTCCTCTCCTTGGAAACTAGACCTCTGGTCCTTCCCTGTC AGTGTTGCTCCCATCTCTTCTCTAACCTTTATTCAGCCCCTTTTCCCTCT GCTGCCAACGGCCTTTTTAGGATCCAACCAAACCACCCTTTCTACCTGCG CACCCTGCCACCCTCTGCACACCTTTAACTGGAGGACTGAGTCACAGATA ATTGTTTCCTTGAAGTCCAGGCCCAGCTGCAGCAACAACAGTCATTAGCC CGTGTCACATCCCTGATCAGAGGGCATCTCCGTGGGGAATCGCCTCCACC CAGCACTGCTGGAAGCCGCGGCTGCCAGGGAGTGGGGCGGCCGGTTCCCT CAGCAGGACCTGGGCTGGCCTCTCCACCTCCCCTAGTAGAGGCGGACCCA TTCCATCTAGTGGCCACCGAGGGTGGGTGGCCCTGAGATGGTGGGCCCTT GACAGGCCTTGTCAGAGCAGAGGGCAGGTGGGAGTCACCTGAAAGCTGAA GGAATGGCTTTAAGGATAGAAGATTTCTCATGACCTCAAGGGATATGAGG GAGGAGCCAGTTTGCCAGGGCTGGGAAAATAATTAGGAGGCCTAGAATCC CTGTTCTCATCTGGGCCTCCGGGGCCAGGGGCAGGGGAATGGCCTGCAGG GCTGGGAGGGGGTACACGCTGTGCGGGGTCTGCCCCTCAGTTGGTGACCT CCTCTCTCTCTCCCCCCAGGAGCCCCAGTGGCACCAGTGACGGGCAGAGG GGACTTGCCATTGCCCCCTCCACCCACCCCCACGACCCCACTCCTGGATC CTTCACCCCAGTGGCCTGCAGACCTCAGCTTCTCCCTCTGAACTTCAAGT CTCCAAAGATCAGAATCTGGGGGAGGGAGCGCGTGCAGGGAGGGGCTTGA TCTCCACATTTTCTCAGGAGTAGTTCGGGCATCCCCATATCTTCTCCTCT CCCCTTGTGAAGAGGACCCAGATCTGGCTTCTTTCCCAAGGAGGGGGTGG GGTGTTCCTCGCGTCCCTGTCCTTGAAGGACCTCCTTCCCCCAGCCTCAT CACCGTGCTCTTCTCAGCGCCACCCTCAGCAGCCAGATTGCAACACCAGG GAGAGGTGGATGCAGAGCCCCACCGGTGGGAAAGTTGCCTGTGGAAGGGA GCCTTTTGCTACAATTTGTAACTTATTTTCTAAAGTCTATTTTGTAACAA TTTATTTAAGTTTAAAAAAAGGAAAACTGCTGCCCCCCAAAAAAAGAAAT TTTC

Gene structure information

H-Inv cluster ID		HIX0012978
Genomic location	Chromosome	16
	Location	16p11.2
	Position	31087223- 31094826
	Strand	+
Possible duplicated location(s)		NA
Gene structure		1 exon(s)
Database links	RefSeq	NM_014699;
	Ensembl	ENST00000300850;  ENST00000394979;  ENST00000428260;  ENST00000439353;
	Entrez Gene	Entrez Gene ID:9726;
	KEGG GENES	KEGG GENES(9726);
	GeneCard	ZNF646;  *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links		H-DBAS;  G-integra;  cDNA-genome alignment;

Predicted CDS information HIP ID HIP000045190 Predicted CDS 424..5913;  1829[aa];  Orientation:+1;  Codon Adaptation Index (CAI). 0.823 Database links RefSeq NA UniProt O15015;  CCDS NA

MEDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRC QQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPE GRRRHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDC ESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLP IPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKH AGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQM LNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV YPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTH KEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRK YPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHT DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACA KHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELE DNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQG DKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATG QPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHPPGIYQC SLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEA LDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAM EMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPR PFRCNQCGKTYRHGGSLVNHRKIHQTGDFLCPVCSRCYPNLAAYRNHLRN HPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVE KLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSE RPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRR IHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFR CGQCGRTYRHAGSLLNHRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSE NRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGL DGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSE APEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHA GDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHN TNKTDRHYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQEL ASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGH GRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGRGHEGSQ EEVGTQWRGKSSPKVGGGARSERREPRGF*

Motif information

	a.a. length	InterPro	Name
	24	IPR015880	Zinc finger, C2H2-like [Domain]
	29	IPR007087	Zinc finger, C2H2-type [Domain]
	22	IPR007087	Zinc finger, C2H2-type [Domain]
	25	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	24	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	28	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	24	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	41	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	25	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	29	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	22	IPR007087	Zinc finger, C2H2-type [Domain]
	25	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	26	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	24	IPR015880	Zinc finger, C2H2-like [Domain]
	29	IPR007087	Zinc finger, C2H2-type [Domain]
	22	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR015880	Zinc finger, C2H2-like [Domain]
	25	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	26	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	24	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	27	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	27	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR015880	Zinc finger, C2H2-like [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	37	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	28	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	24	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]
	38	IPR013087	Zinc finger, C2H2-type/integrase, DNA-binding [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	22	IPR007087	Zinc finger, C2H2-type [Domain]
	23	IPR015880	Zinc finger, C2H2-like [Domain]
	28	IPR007087	Zinc finger, C2H2-type [Domain]
	21	IPR007087	Zinc finger, C2H2-type [Domain]

Gene function information

H-Inv ID		HIT000000003
H-Inv cluster ID		HIX0012978
Accession number		AB002294.1
CAGE tag ID		NA
EST ID		NA
Transcript feature		NO;
Coding potential		Protein coding;
Definition		Similar to Uncharacterized protein; Fragment;
Similarity category		Category: Similar to known protein(Category II).
		Similar to known protein (F1PZT2)  [Identity/coverage = 98.113%/100.0%] to Canis familiaris (Dog) (Canis lupus familiaris). protein.
Experimental evidence		Protein evidence
PubMed ID		16341006;  ALL;
Gene family/group	H-Inv gene family/group ID	HIF0000005
	Gene family/group name	Putative Zinc finger, C2H2-type (IPR007087).
	Evidence motif (InterPro) ID	IPR007087
Gene symbol/name	HGNC symbol	ZNF646
	HGNC aliases	NA
	HGNC name	zinc finger protein 646
	DDBJ	KIAA0296
	UniProt	ZNF646
EC number		NA
GGDB (GlycoGene Database)	Gene symbol	NA
	Familly	NA
	Designation	NA
	Expression	NA
KEGG metabolic pathway		NA
Protein-protein interaction (PPI)	H-Inv protein ID	HIP000045190
	No. of interaction	31
	Interaction partner(s)	HIP000004641;  HIP000019806;  HIP000023088;  HIP000027985;  HIP000030139;  HIP000030139;  HIP000040979;  HIP000040979;  HIP000046539;  HIP000050218;  HIP000051100;  HIP000058525;  HIP000060909;  HIP000060909;  HIP000061444;  HIP000065024;  HIP000066804;  HIP000076726;  HIP000076726;  HIP000083362;  HIP000087753;  HIP000090103;  HIP000092761;  HIP000097588;  HIP000099677;  HIP000103357;  HIP000103357;  HIP000104459;  HIP000112902;  HIP000174448;  HIP000436453;
	BIND	144515;  176588;  177534;  295656;  55271;  55314;
	DIP	102977E;
	MINT	MINT-17109;  MINT-17110;  MINT-56616;  MINT-56617;  MINT-56618;  MINT-56619;  MINT-56621;  MINT-56626;  MINT-6550679;  MINT-6550697;  MINT-6550709;  MINT-6550722;  MINT-6550731;  MINT-6550741;  MINT-6550759;  MINT-6550777;  MINT-6550791;  MINT-6603869;  MINT-7026649;  MINT-7026658;  MINT-8048571;  MINT-8048594;  MINT-8048620;
	HPRD	00138;  00207;  00616;  00950;  01842;  01867;  03047;  03690;  04668;  05572;  06121;  06159;  07315;  09038;  10440;  12004;  13173;  13853;  14647;  17822;
	IntAct	EBI-707234;  EBI-706526;  EBI-707195;  EBI-706513;  EBI-372028;  EBI-2321764;  EBI-372023;  EBI-2515634;  EBI-2337046;  EBI-372011;  EBI-368090;  EBI-372004;  EBI-5241273;  EBI-5241252;  EBI-5241230;  EBI-5241217;  EBI-4370616;  EBI-706506;  EBI-5241242;  EBI-5241265;  EBI-706461;  EBI-5260058;  EBI-706488;  EBI-706437;  EBI-706420;  EBI-706482;  EBI-706633;  EBI-706726;  EBI-706570;  EBI-707161;  EBI-706549;  EBI-707182;  EBI-706533;  EBI-706714;  EBI-706680;  EBI-706668;  EBI-706703;  EBI-706693;  EBI-707130;  EBI-706864;  EBI-706961;  EBI-706884;  EBI-706740;  EBI-706943;  EBI-706923;  EBI-706931;  EBI-706989;  EBI-707108;  EBI-706971;  EBI-707096;  EBI-707088;  EBI-707007;  EBI-707457;  EBI-707448;  EBI-707245;  EBI-707517;  EBI-707478;  EBI-707473;  EBI-707657;  EBI-711124;  EBI-708467;  EBI-708264;  EBI-707699;  EBI-707684;  EBI-707691;  EBI-708448;  EBI-708337;  EBI-708277;  EBI-708308;  EBI-708435;  EBI-708394;  EBI-708423;  EBI-711136;  EBI-711129;
Database links	RefSeq	NM_014699;
	Ensembl	ENST00000300850;  ENST00000394979;  ENST00000428260;  ENST00000439353;
	Entrez Gene	Entrez Gene ID:9726;
	KEGG GENES	KEGG GENES(9726);
	GeneCard	ZNF646;  *GeneCards is provided free to academic non-profit institutions.
	etc	Human-Gene diversity Of Life-style related Diseases;
Curation status		Auto-annotated
Notes		NA
Related H-InvDB links		Putative Zinc finger, C2H2-type (IPR007087). Similarity Search Tool;  TACT;

fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome.

NA

Gene ontology information

Molecular function	zinc ion binding (GO:0008270);  nucleic acid binding (GO:0003676);
Cellular component	intracellular (GO:0005622);

Subcellular localization information

Last modified:20-Apr-2012

WoLF PSORT	nuclear;  cytosol;
Target P	Other
SOSUI	soluble protein
TMHMM	soluble protein
PTS1	Not targeted
Related H-InvDB links	LIFEdb;  JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP)

Last modified:20-Apr-2012

Start End PDB_ID E-value Identity Coverage SCOP_ID 10 97 1k2fA 3e-07 6.7 76/190 b.8.1.2 236 320 1ny8A 9e-11 4.7 84/97 d.52.6.1 281 408 1qk9A 3e-05 7.0 76/92 d.10.1.3 379 424 1yuiA 5e-04 17.0 46/54 g.37.1.1 463 521 1k2fA 4e-06 8.2 59/190 b.8.1.2 575 656 1qk9A 5e-05 8.5 68/92 d.10.1.3 821 900 1rhyA2 2e-04 8.1 75/94 d.14.1.9 1050 1088 2eppA1 2e-05 19.5 38/53 g.37.1.1 1200 1350 1fs7A 4e-15 13.0 138/471 a.138.1.3 1533 1613 1k2fA 2e-06 6.0 81/190 b.8.1.2 1673 1772 2czrA1 8e-10 8.0 100/218 c.52.4.1

Related H-InvDB links GTOP

Gene expression information

Last modified:20-Apr-2012

Tissue-specific expression			NA
Probe information	AceGene		AGhsA151210;
	Affymetrix GeneChip	HG-Focus	NA
		HG-U133	NA
		HG-U133A	NA
		HG-U133A_2	NA
		HG-U133B	NA
		HG-U133_Plus_2	NA
		HG-U95	NA
		HG-U95A	NA
		HG-U95B	NA
		HG-U95C	NA
		HG-U95D	NA
		HG-U95E	NA
		HG-U95Av2	NA
		HuEx-1_0	3490997;  3491001;  3515298;  3656806;  3656807;  3656808;  3656809;  3656810;  3656811;  3656812;  3656813;  3656814;  3656815;  3656816;  3656817;  3656818;  3656819;  3656820;
		HuGeneFL	NA
	Agilent	Human 1A Oligo Microarray:PGID215	NA
		Whole Human Genome Oligo Microarray:PGID247	NA
Related H-InvDB links			H-ANGEL;  DNAProbeLocator;

Disease/pathology information

Last modified:20-Apr-2012

Disease relation		Disease name:NA
Related information in OMIM		OMIM ID:NA Title:NA
Co-localized orphan diseases		OMIM ID:  156850;  605013;  605021;  606668;  607339;  608558;  608903;  610260;
Disease related mutation		NA
Literature-Extracted GENe-Disease Associations (LEGENDA)	Gene name	Entrez Gene ID:(9726)
	Disease	Entrez Gene ID:(9726)
	Substance	Entrez Gene ID:(9726)
Related H-InvDB links		DiseaseInfo Viewer;  LEGENDA;

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Single Nucleotide Polymorphism (SNP) and indel  Location Variation dbSNP ID Strand CDS/UTR Translation 11 .. 11 C/T rs55874500 + 5'UTR 92 .. 92 C/G rs75489496 + 5'UTR 107 .. 107 T/C rs3751853 + 5'UTR 716 .. 716 C/T rs28407985 + CDS Nonsynonymous[Ala98Val] 996 .. 996 T/A rs111604081 + CDS Synonymous[Thr191Thr] 1125 .. 1125 G/A rs749671 - CDS Synonymous[Glu234Glu] 1403 .. 1403 A/G rs749670 - CDS Nonsynonymous[Glu327Gly] 1516 .. 1516 G/A rs77579502 + CDS Nonsynonymous[Asp365Asn] 1996 .. 1996 G/A rs112578158 + CDS Nonsynonymous[Gly525Arg] 2119 .. 2119 A/G rs35041466 - CDS Nonsynonymous[Thr566Ala] 2195 .. 2195 A/T rs113882348 + CDS Nonsynonymous[Glu591Val] 2310 .. 2310 A/T rs72785532 + CDS Synonymous[Ser629Ser] 2429 .. 2429 G/A rs75918054 + CDS Nonsynonymous[Arg669Gln] 2745 .. 2745 C/G rs17641067 + CDS Nonsynonymous[Ile774Met] 2872 .. 2872 G/C rs78522165 + CDS Nonsynonymous[Ala817Pro] 3047 .. 3047 C/T rs75586809 + CDS Nonsynonymous[Ala875Val] 3048 .. 3048 G/A rs77095523 + CDS Synonymous[Ala875Ala] 3185 .. 3185 G/C rs35713203 - CDS Nonsynonymous[Gly921Ala] 3219 .. 3219 A/C rs34223943 - CDS Synonymous[Pro932Pro] 3230 .. 3230 C/T rs28735175 + CDS Nonsynonymous[Ser936Leu] 3423 .. 3423 G/C rs117702332 + CDS Nonsynonymous[Met1000Ile] 3854 .. 3854 C/T rs113926102 + CDS Nonsynonymous[Pro1144Leu] 3951 .. 3951 T/C rs75521363 + CDS Synonymous[Thr1176Thr] 3987 .. 3987 T/A/C rs3751855 + CDS 4092 .. 4092 G/A rs62057086 + CDS Synonymous[Gln1223Gln] 4168 .. 4168 C/T rs35376811 - CDS Nonsynonymous[Arg1249Trp] 4376 .. 4376 G/A rs3751856 + CDS Nonsynonymous[Arg1318Gln] 4535 .. 4535 G/A rs77439178 + CDS Nonsynonymous[Arg1371His] 4671 .. 4671 A/G rs117506794 + CDS Synonymous[Leu1416Leu] 4763 .. 4763 C/A rs75083396 + CDS Nonsynonymous[Ala1447Glu] 4789 .. 4789 T/G rs114072963 + CDS Nonsynonymous[Ser1456Ala] 4806 .. 4806 G/A rs36052073 - CDS Synonymous[Lys1461Lys] 4853 .. 4853 G/A rs7196726 + CDS Nonsynonymous[Gly1477Asp] 5211 .. 5211 C/A rs61729520 + CDS Synonymous[Ser1596Ser] 5314 .. 5314 G/A rs79791004 + CDS Nonsynonymous[Asp1631Asn] 5423 .. 5423 C/A rs80281572 + CDS Nonsynonymous[Ser1667Tyr] 5721 .. 5721 T/C rs116190456 + CDS Synonymous[Cys1766Cys] 5786 .. 5786 C/T rs34259949 - CDS Nonsynonymous[Thr1788Met] 5850 ^ 5851 -/G rs35715982 - CDS 6041 .. 6041 G/A rs117819187 + 3'UTR 6296 .. 6296 G/A rs77478478 + 3'UTR 6456 .. 6456 C/A rs78066951 + 3'UTR 6670 .. 6670 G/A rs889550 + 3'UTR 6732 .. 6732 C/T rs750952 + 3'UTR 6867 .. 6867 T/C rs750953 + 3'UTR 7092 .. 7092 G/A rs114426073 + 3'UTR 7305 .. 7305 T/C rs2077633 - 3'UTR 7370 ^ 7371 -/C rs34896559 - 3'UTR 7429 .. 7429 G/A rs2007636 - 3'UTR 7457 .. 7457 T/C rs72785535 + 3'UTR 7525 .. 7525 A/T rs3180955 - 3'UTR  Microsatellite (Short Tandem Repeat, STR) No data available  Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD) No data available

Repeat  No data available Database links Human-Gene diversity Of Life-style related Diseases(H-GOLD);  Related H-InvDB links VaryGene;  Repeat Mask Viewer;