H-InvDB x AHG DB
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H-InvDB_8.3 released on March 26, 2013.
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H-Inv cluster ID: HIX0035947 Created date: 26-Mar-2013 Last modified: 20-Apr-2012
Definition: CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
 
 

Gene structure  G-integra H-DBAS
H-Inv cluster ID HIX0035947
Genomic location  G-integra Help Chromosome 11
Location 11p15.2
Position 14665269- 14893605
Strand +
Antisense cluster ID(s) NA
Database links RefSeq NM_000922; 
Ensembl ENST00000534317;  ENST00000455098;  ENST00000525439;  ENST00000282096; 
Entrez Gene Entrez Gene ID:5140; 
KEGG GENES KEGG GENES(5140); 
GeneCard GeneCardPDE3B;  *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Cluster member H-Inv ID(s) HIT000254801;  HIT000435803;  HIT000500578;  HIT000500579;  HIT000502674;  HIT000324912;  HIT000329261; 
Additional cluster member candidate(s) NA
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA multiple alignmentcDNA-genome multiple alignment;  ORF multiple alignmentORF multiple alignment; 
Mini-G Locus map Locus map

 
TOP 1-7 LAST 
Cluster member (s)  G-integra H-DBAS
Locus member number 1
H-Inv ID Transcript viewHIT000254801
Accession number AY459346.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665331- 14892350
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 2
H-Inv ID Transcript viewHIT000435803
Accession number BC150307.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 99.82%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature NA
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665269- 14891629
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 3
H-Inv ID Transcript viewHIT000500578
Accession number BC136565.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature NA
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665377- 14891440
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 4
H-Inv ID Transcript viewHIT000500579
Accession number BC136566.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature NA
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665377- 14891440
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 5
H-Inv ID Transcript viewHIT000502674
Accession number BC144248.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 99.906%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665377- 14891440
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 6
H-Inv ID Transcript viewHIT000324912
Accession number X95520.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 99.82%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature NA
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665622- 14891206
Strand +
Gene structure 16 exons
 
TOP 1-7 LAST 
Locus member number 7
H-Inv ID Transcript viewHIT000329261
Accession number AB209326.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (NP_000913)  [Identity/coverage = 99.293%/25.45%] to Homo sapiens protein.
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 11
Location 11p15.2
Position 14665806- 14798209
Strand +
Gene structure 2 exons

Alternative splicing (AS) information  G-integra H-DBAS
Pattern of alternative splicing isoforms 3' terminal AS;  Internal AS; 
Position of alternative splicing isoforms Internal donor site; 
Alternative splicing isoform H-Inv ID(s) Splicing isoformHIT000254801;  Splicing isoformHIT000502674;  Splicing isoformHIT000329261; 
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA multiple alignmentcDNA-genome multiple alignment;  ORF multiple alignmentORF multiple alignment; 

Gene function information  G-integra PPI viewer H-DBAS Gene family Similarity Search Tool TACT
H-Inv cluster ID HIX0035947
Representative H-Inv ID Representative H-Inv IDHIT000254801
Accession number AY459346.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition CGMP-inhibited 3',5'-cyclic phosphodiesterase B.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_000913)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene family/group Gene family H-Inv gene family/group ID HIF0001864
Gene family/group name Putative 3'5'-cyclic nucleotide phosphodiesterase (IPR002073).
Evidence motif (InterPro) ID IPR002073
Gene symbol/name HGNC symbol PDE3B 
HGNC aliases NA
HGNC name phosphodiesterase 3B, cGMP-inhibited 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000093972
No. of interaction 1
Interaction partner(s) HIP000033270; 
BIND NA
DIP NA
MINT NA
HPRD 02736; 
IntAct NA
Database links RefSeq NM_000922; 
Ensembl ENST00000534317;  ENST00000455098;  ENST00000525439;  ENST00000282096; 
Entrez Gene Entrez Gene ID:5140; 
KEGG GENES KEGG GENES(5140); 
GeneCard GeneCardPDE3B;  *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Related H-InvDB links G-integraG-integra;  PPI viewerPPI view;  H-DBASH-DBAS;  Putative 3'5'-cyclic nucleotide phosphodiesterase (IPR002073). Similarity Search ToolSimilarity search tool;  TACTTACT; 
Gene expression information   H-ANGEL DNAProbeLocator Last modified:20-Apr-2012
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator		 AceGene AGhsA041002; 
Affymetrix
GeneChip		 HG-Focus 208591_s_at; 
HG-U133 208591_s_at;  231276_at; 
HG-U133A 208591_s_at; 
HG-U133A_2 208591_s_at; 
HG-U133B 231276_at; 
HG-U133_Plus_2 208591_s_at;  231276_at; 
HG-U95 35872_at;  43859_g_at;  746_at; 
HG-U95A 35872_at;  746_at; 
HG-U95B 43859_g_at; 
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 3321521;  3321522;  3321523;  3321524;  3321525;  3321526;  3321542;  3321547;  3321550;  3321552;  3321554;  3321555;  3321556;  3321559;  3321560;  3321561;  3321562;  3321563;  3321564;  3321567;  3321569;  3321572;  3321573;  3321575;  3321576;  3321577;  3364055;  3364056;  3364057;  3364071; 
HuGeneFL D50640_at; 
Agilent Human 1A Oligo Microarray:PGID215 A_23_P116114; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P116114; 
Related H-InvDB links H-ANGELH-ANGEL;  DNAProbeLocatorDNAProbeLocator; 

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:20-Apr-2012
Disease relation Disease name:NA
Related information in OMIM OMIM ID:NA Title:NA
Co-localized orphan diseases OMIM ID:  604499;  609270;  609470;  611010; 
Disease related mutation NA
Co-occurred words and phrases with this gene name in PubMed (LEGENDA) LEGENDA Gene name Entrez Gene ID:(5140); 
Disease Entrez Gene ID:(5140); 
Gene function Entrez Gene ID:(5140); 
Substance Entrez Gene ID:(5140); 
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo Viewer;  LEGENDALEGENDA;