H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Inv cluster ID: HIX0034291 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
 
 

Gene structure  G-integra H-DBAS
H-Inv cluster ID HIX0034291
Genomic location  G-integra Help Chromosome 8
Location 8p11.22
Position 39442008- 39587583
Strand +
Antisense cluster ID(s) NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:8749
KEGG GENES KEGG GENES(8749)
GeneCard GeneCardADAM18*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Cluster member H-Inv ID(s) HIT000432827HIT000388242HIT000244761HIT000252365HIT000388243HIT000093511HIT000264237HIT000384874
Additional cluster member candidate(s) NA
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment
Mini-G Locus map Locus map

 
TOP 1-8 LAST 
Cluster member (s)  G-integra H-DBAS
Locus member number 1
H-Inv ID Transcript viewHIT000432827
Accession number AK313961.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9Y3Q7)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442097- 39587459
Strand +
Gene structure 20 exons
 
TOP 1-8 LAST 
Locus member number 2
H-Inv ID Transcript viewHIT000388242
Accession number BC121045.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9Y3Q7)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature NA
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442142- 39587487
Strand +
Gene structure 20 exons
 
TOP 1-8 LAST 
Locus member number 3
H-Inv ID Transcript viewHIT000244761
Accession number AJ133004.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9Y3Q7)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature NA
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442142- 39587487
Strand +
Gene structure 20 exons
 
TOP 1-8 LAST 
Locus member number 4
H-Inv ID Transcript viewHIT000252365
Accession number AY358321.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y3Q7)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442100- 39587583
Strand +
Gene structure 19 exons
 
TOP 1-8 LAST 
Locus member number 5
H-Inv ID Transcript viewHIT000388243
Accession number BC121046.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y3Q7)  [Identity/coverage = 99.697%/44.65%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442142- 39587487
Strand +
Gene structure 18 exons
 
TOP 1-8 LAST 
Locus member number 6
H-Inv ID Transcript viewHIT000093511
Accession number BC034624.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q95194)  [Identity/coverage = 94.253%/23.32%] to Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442107- 39469094
Strand +
Gene structure 6 exons
 
TOP 1-8 LAST 
Locus member number 7
H-Inv ID Transcript viewHIT000264237
Accession number BC070279.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q95194)  [Identity/coverage = 94.253%/23.32%] to Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature NA
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442104- 39468757
Strand +
Gene structure 6 exons
 
TOP 1-8 LAST 
Locus member number 8
H-Inv ID Transcript viewHIT000384874
Accession number AK225744.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y3Q7)  [Identity/coverage = 81.659%/32.34%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Transcript feature NA
Genomic location  G-integra Chromosome 8
Location 8p11.22
Position 39442150- 39468377
Strand +
Gene structure 6 exons

Alternative splicing (AS) information  G-integra H-DBAS
Pattern of alternative splicing isoforms 3' terminal AS;  Internal AS; 
Position of alternative splicing isoforms Cassette; 
Alternative splicing isoform H-Inv ID(s) Splicing isoformHIT000388243Splicing isoformHIT000252365Splicing isoformHIT000432827Splicing isoformHIT000093511
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment

Gene function information  G-integra PPI viewer H-DBAS Gene family Similarity Search Tool TACT
H-Inv cluster ID HIX0034291
Representative H-Inv ID Representative H-Inv IDHIT000432827
Accession number AK313961.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9Y3Q7)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene family/group Gene family H-Inv gene family/group ID HIF0000033
Gene family/group name Blood coagulation inhibitor, Disintegrin (IPR001762).
Evidence motif (InterPro) ID 3
Gene symbol/name HGNC symbol ADAM18 
HGNC aliases "a disintegrin and metalloproteinase domain 18" 
HGNC name ADAM metallopeptidase domain 18 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000053035
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:8749
KEGG GENES KEGG GENES(8749)
GeneCard GeneCardADAM18*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Related H-InvDB links G-integraG-integra PPI viewerPPI view H-DBASH-DBAS Blood coagulation inhibitor, Disintegrin (IPR001762). Similarity Search ToolSimilarity search tool TACTTACT