H-InvDB x AHG DB
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H-InvDB_8.3 released on March 26, 2013.
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H-Inv cluster ID: HIX0012315 Created date: 26-Mar-2013 Last modified: 20-Apr-2012
Definition: Similar to Talin-2;
 
 

Gene structure  G-integra H-DBAS
H-Inv cluster ID HIX0012315
Genomic location  G-integra Help Chromosome 15
Location 15q22.2
Position 62939510- 63136830
Strand +
Antisense cluster ID(s) NA
Database links RefSeq NM_015059; 
Ensembl ENST00000494733;  ENST00000489129;  ENST00000306829;  ENST00000474847;  ENST00000467297;  ENST00000472902; 
Entrez Gene Entrez Gene ID:83660; 
KEGG GENES KEGG GENES(83660); 
GeneCard GeneCardTLN2;  *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Cluster member H-Inv ID(s) HIT000000026;  HIT000056301;  HIT000056791;  HIT000056793;  HIT000489194;  HIT000079120;  HIT000065694;  HIT000061887;  HIT000066789;  HIT000450890; 
Additional cluster member candidate(s) NA
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA multiple alignmentcDNA-genome multiple alignment;  ORF multiple alignmentORF multiple alignment; 
Mini-G Locus map Locus map

 
TOP 1-10 LAST 
Cluster member (s)  G-integra H-DBAS
Locus member number 1
H-Inv ID Transcript viewHIT000000026
Accession number AB002318.2
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 100.0%/76.04%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature Representative H-Inv IDRepresentative transcript; 
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 62994321- 63133680
Strand +
Gene structure 42 exons
 
TOP 1-10 LAST 
Locus member number 2
H-Inv ID Transcript viewHIT000056301
Accession number BX647654.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 99.758%/49.1%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63032644- 63133685
Strand +
Gene structure 28 exons
 
TOP 1-10 LAST 
Locus member number 3
H-Inv ID Transcript viewHIT000056791
Accession number BX648144.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 98.645%/14.52%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63050789- 63077040
Strand +
Gene structure 9 exons
 
TOP 1-10 LAST 
Locus member number 4
H-Inv ID Transcript viewHIT000056793
Accession number BX648146.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 98.645%/14.52%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63050789- 63077040
Strand +
Gene structure 9 exons
 
TOP 1-10 LAST 
Locus member number 5
H-Inv ID Transcript viewHIT000489194
Accession number AK294570.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 100.0%/9.36%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63112720- 63133437
Strand +
Gene structure 6 exons
 
TOP 1-10 LAST 
Locus member number 6
H-Inv ID Transcript viewHIT000079120
Accession number AF402000.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Talin-2;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9Y4G6)  [Identity/coverage = 99.921%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 62939510- 63132809
Strand +
Gene structure 56 exons
 
TOP 1-10 LAST 
Locus member number 7
H-Inv ID Transcript viewHIT000065694
Accession number AF070527.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Hypothetical protein.
Similarity category  Help Category: Hypothetical protein(Category V).
Hypothetical protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63135274- 63136828
Strand +
Gene structure 1 exons
 
TOP 1-10 LAST 
Locus member number 8
H-Inv ID Transcript viewHIT000061887
Accession number AF007154.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Hypothetical short protein.
Similarity category  Help Category: Hypothetical short protein(Category VI).
Hypothetical short protein.
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63135370- 63136828
Strand +
Gene structure 1 exons
 
TOP 1-10 LAST 
Locus member number 9
H-Inv ID Transcript viewHIT000066789
Accession number AF085910.1
CAGE tag ID NA
EST ID NA
Coding potential Non-protein-coding; 
Definition Non-protein-coding transcript, uncharacterized transcript.
Similarity category  Help Category: Non-protein coding transcript.
NA
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63133189- 63133691
Strand +
Gene structure 1 exons
 
TOP 1-10 LAST 
Locus member number 10
H-Inv ID Transcript viewHIT000450890
Accession number DQ584359.1
CAGE tag ID NA
EST ID NA
Coding potential Non-protein-coding; 
Definition Non-protein-coding transcript, uncharacterized transcript.
Similarity category  Help Category: Non-protein coding transcript.
NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
Transcript feature NA
Genomic location  G-integra Chromosome 15
Location 15q22.2
Position 63092638- 63092666
Strand +
Gene structure 1 exons

Alternative splicing (AS) information  G-integra H-DBAS
Pattern of alternative splicing isoforms 5' terminal AS;  3' terminal AS;  Internal AS; 
Position of alternative splicing isoforms NA
Alternative splicing isoform H-Inv ID(s) Splicing isoformHIT000056301;  Splicing isoformHIT000079120;  Splicing isoformHIT000056791; 
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA multiple alignmentcDNA-genome multiple alignment;  ORF multiple alignmentORF multiple alignment; 

Gene function information  G-integra PPI viewer H-DBAS Gene family Similarity Search Tool TACT
H-Inv cluster ID HIX0012315
Representative H-Inv ID Representative H-Inv IDHIT000000026
Accession number AB002318.2
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Talin-2;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q9Y4G6)  [Identity/coverage = 100.0%/76.04%] to Homo sapiens (Human). protein.
Gene family/group Gene family H-Inv gene family/group ID HIF0004216
Gene family/group name Human gene family/group candidate, HIF0004216.
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol TLN2 
HGNC aliases NA
HGNC name talin 2 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000004858
No. of interaction 12
Interaction partner(s) HIP000036282;  HIP000113956;  HIP000117203;  HIP000162615;  HIP000164099;  HIP000174980;  HIP000193291;  HIP000195643;  HIP000195643;  HIP000304632;  HIP000361482;  HIP000361704; 
BIND NA
DIP NA
MINT NA
HPRD 11886; 
IntAct EBI-943199;  EBI-1239817;  EBI-1239278;  EBI-943146;  EBI-1241315;  EBI-943222;  EBI-943284;  EBI-1241924;  EBI-4481581;  EBI-1244257;  EBI-1243464;  EBI-1242778;  EBI-943216;  EBI-943134;  EBI-4481594;  EBI-942660;  EBI-942864;  EBI-943204;  EBI-942828;  EBI-942759;  EBI-943332;  EBI-969994;  EBI-969974;  EBI-943508;  EBI-943430;  EBI-970034; 
Database links RefSeq NM_015059; 
Ensembl ENST00000494733;  ENST00000489129;  ENST00000306829;  ENST00000474847;  ENST00000467297;  ENST00000472902; 
Entrez Gene Entrez Gene ID:83660; 
KEGG GENES KEGG GENES(83660); 
GeneCard GeneCardTLN2;  *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Related H-InvDB links G-integraG-integra;  PPI viewerPPI view;  H-DBASH-DBAS;  Human gene family/group candidate, HIF0004216. Similarity Search ToolSimilarity search tool;  TACTTACT; 
Gene expression information   H-ANGEL DNAProbeLocator Last modified:20-Apr-2012
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator		 AceGene AGhsB010603; 
Affymetrix
GeneChip		 HG-Focus NA
HG-U133 212703_at; 
HG-U133A 212703_at; 
HG-U133A_2 212703_at; 
HG-U133B NA
HG-U133_Plus_2 212703_at; 
HG-U95 NA
HG-U95A NA
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 3597170;  3597171;  3597173;  3597174;  3597175;  3597176;  3597177;  3597179;  3597180;  3597181;  3597183;  3597184;  3597188;  3597189;  3597190;  3597192;  3597194;  3597198;  3597199;  3597200;  3597201;  3597203;  3597208;  3597209;  3597211;  3597212;  3597215;  3597216;  3597218;  3597221;  3597226;  3597228;  3597229;  3597231;  3597232;  3597234;  3597235;  3597240;  3597241;  3597246;  3597247;  3597261;  3597263;  3597266;  3597267;  3597268; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P250651; 
Whole Human Genome Oligo Microarray:PGID247 A_24_P347566; 
Related H-InvDB links H-ANGELH-ANGEL;  DNAProbeLocatorDNAProbeLocator; 

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:20-Apr-2012
Disease relation Disease name:NA
Related information in OMIM OMIM ID:NA Title:NA
Co-localized orphan diseases OMIM ID:  105600;  122460;  148600;  214900;  604329;  605728;  609273;  611274;  612632; 
Disease related mutation NA
Co-occurred words and phrases with this gene name in PubMed (LEGENDA) LEGENDA Gene name Entrez Gene ID:(83660); 
Disease Entrez Gene ID:(83660); 
Gene function Entrez Gene ID:(83660); 
Substance Entrez Gene ID:(83660); 
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo Viewer;  LEGENDALEGENDA;