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H-InvDB_9.0 released on May 27, 2015.
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H-Inv cluster ID: HIX0005159 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Interferon regulatory factor 1; IRF-1;
 
 

<?xml version="1.0" standalone="yes" ?>
<H-Inv>
  <LOCUSXML>
    <CLUSTER-ID>HIX0005159</CLUSTER-ID>
    <CLUSTER-ID-VERSION>HIX0005159.19</CLUSTER-ID-VERSION>
    <REP-H-INVITATIONAL-ID>HIT000034397</REP-H-INVITATIONAL-ID>
    <REP-H-INVITATIONAL-ID-VERSION>HIT000034397.19</REP-H-INVITATIONAL-ID-VERSION>
    <REP-ACCESSION-NO>BC009483</REP-ACCESSION-NO>
    <REP-ACCESSION-NO-VERSION>BC009483.2</REP-ACCESSION-NO-VERSION>
    <REP-DEFINITION>Interferon regulatory factor 1; IRF-1;</REP-DEFINITION>
    <GENOME-STATISTICS>build 37.1</GENOME-STATISTICS>
    <DATE-CREATED>26-Mar-2013</DATE-CREATED>
    <DATE-LAST-UPDATE>27-May-2015</DATE-LAST-UPDATE>
    <DATE-LAST-MODIFIED>27-May-2015</DATE-LAST-MODIFIED>
    <H-INV-DB-RELEASE>9.0</H-INV-DB-RELEASE>
    <HIX-RELEASE>9.0</HIX-RELEASE>
    <DATE-ANNOTATION-LAST-UPDATE>27-May-2015</DATE-ANNOTATION-LAST-UPDATE>
    <DATE-ANNOTATION-LAST-MODIFIED>27-May-2015</DATE-ANNOTATION-LAST-MODIFIED>
    <HIX-ANNOTATION-RELEASE>9.0</HIX-ANNOTATION-RELEASE>
    <HGNC>
      <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
      <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
    </HGNC>
    <CHROMOSOME-NUMBER>5</CHROMOSOME-NUMBER>
    <BAND_CHROMOSOME-BAND>5q31.1</BAND_CHROMOSOME-BAND>
    <CLUSTER_START>131776132</CLUSTER_START>
    <CLUSTER_END>131826490</CLUSTER_END>
    <CLUSTER_STRAND>-</CLUSTER_STRAND>
    <EXPRESSION>
      <EXPRESSION_DATE-LAST-UPDATE>27-May-2015</EXPRESSION_DATE-LAST-UPDATE>
      <EXPRESSION_DATE-LAST-MODIFIED>27-May-2015</EXPRESSION_DATE-LAST-MODIFIED>
      <EXPRESSION-RELEASE>9.0</EXPRESSION-RELEASE>
      <PROBE-MAPPING>
        <PLATFORM>
          <PLATFORM-TYPE>AceGene</PLATFORM-TYPE>
          <PROBE>
            <PROBE-TYPE>AceGene</PROBE-TYPE>
            <PROBE-ID>AGhsA220418</PROBE-ID>
          </PROBE>
        </PLATFORM>
        <PLATFORM>
          <PLATFORM-TYPE>Affymetrix GeneChip</PLATFORM-TYPE>
          <PROBE>
            <PROBE-TYPE>HG-Focus</PROBE-TYPE>
            <PROBE-ID>202531_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U133</PROBE-TYPE>
            <PROBE-ID>202531_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U133A</PROBE-TYPE>
            <PROBE-ID>202531_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U133A_2</PROBE-TYPE>
            <PROBE-ID>202531_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U133_Plus_2</PROBE-TYPE>
            <PROBE-ID>202531_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U95</PROBE-TYPE>
            <PROBE-ID>669_s_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG-U95A</PROBE-TYPE>
            <PROBE-ID>669_s_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HG_U95Av2</PROBE-TYPE>
            <PROBE-ID>669_s_at</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HuEx-1_0</PROBE-TYPE>
            <PROBE-ID>2828595</PROBE-ID>
            <PROBE-ID>2875350</PROBE-ID>
            <PROBE-ID>2875351</PROBE-ID>
            <PROBE-ID>2875353</PROBE-ID>
            <PROBE-ID>2875356</PROBE-ID>
            <PROBE-ID>2875358</PROBE-ID>
            <PROBE-ID>2875360</PROBE-ID>
            <PROBE-ID>2875362</PROBE-ID>
            <PROBE-ID>2875363</PROBE-ID>
            <PROBE-ID>2875364</PROBE-ID>
            <PROBE-ID>2875365</PROBE-ID>
            <PROBE-ID>2875366</PROBE-ID>
            <PROBE-ID>2875372</PROBE-ID>
            <PROBE-ID>2875375</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>HuGeneFL</PROBE-TYPE>
            <PROBE-ID>L05072_s_at</PROBE-ID>
          </PROBE>
        </PLATFORM>
        <PLATFORM>
          <PLATFORM-TYPE>Agilent probe set</PLATFORM-TYPE>
          <PROBE>
            <PROBE-TYPE>Human 1A Oligo Microarray:PGID215</PROBE-TYPE>
            <PROBE-ID>A_23_P41765</PROBE-ID>
          </PROBE>
          <PROBE>
            <PROBE-TYPE>Whole Human Genome Oligo Microarray:PGID247</PROBE-TYPE>
            <PROBE-ID>A_23_P41765</PROBE-ID>
          </PROBE>
        </PLATFORM>
      </PROBE-MAPPING>
    </EXPRESSION>
    <AS-PATTERN>5'terminal AS Suggested.</AS-PATTERN>
    <AS-PATTERN>3'terminal AS Suggested.</AS-PATTERN>
    <AS-PATTERN>Internal AS Suggested.</AS-PATTERN>
    <AS-PATTERN>Cassette Suggested.</AS-PATTERN>
    <AS-PATTERN>Internal acceptor site Suggested.</AS-PATTERN>
    <AS-PATTERN>Retained intron Suggested.</AS-PATTERN>
    <SPLICING-ISOFORM_H-INVITATIONAL-ID>HIT000034397</SPLICING-ISOFORM_H-INVITATIONAL-ID>
    <SPLICING-ISOFORM_H-INVITATIONAL-ID>HIT000329559</SPLICING-ISOFORM_H-INVITATIONAL-ID>
    <SPLICING-ISOFORM_H-INVITATIONAL-ID>HIT000493394</SPLICING-ISOFORM_H-INVITATIONAL-ID>
    <ANTISENSE-CLUSTER>
      <CLUSTER-ID>HIX0200727</CLUSTER-ID>
      <OVERLAP-TYPE>overlap at CDSs (all)</OVERLAP-TYPE>
    </ANTISENSE-CLUSTER>
    <MAPPED>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000034397</MEMBER_H-INVITATIONAL-ID>
        <MEMBER_H-INVITATIONAL-ID-VERSION>HIT000034397.19</MEMBER_H-INVITATIONAL-ID-VERSION>
        <MEMBER_ACCESSION-NO>BC009483</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>BC009483.2</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HUM</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID>HIP000084307</MEMBER_H-INVITATIONAL-PROTEIN-ID>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000084307.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Human curated</MEMBER_CURATION-STATUS>
        <MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>P10914</MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>
        <MEMBER_DATA-SOURCE_IDENTITY>100.0</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>100.0</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Identical to known human protein(Category I).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
        </HGNC>
        <MEMBER_DB-REFERENCE_ENTREZGENE>3659</MEMBER_DB-REFERENCE_ENTREZGENE>
        <MEMBER_GENOME_START>131818780</MEMBER_GENOME_START>
        <MEMBER_GENOME_END>131826434</MEMBER_GENOME_END>
        <MEMBER_LOCUS_START>42649</MEMBER_LOCUS_START>
        <MEMBER_LOCUS_END>50303</MEMBER_LOCUS_END>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>198</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>199</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>290</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>291</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>390</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>391</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>567</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>568</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>617</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>618</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>747</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>748</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>870</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>871</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>920</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>921</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>1056</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1057</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>2061</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131826237</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131826434</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131825084</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131825175</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131823618</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131823717</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822646</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822822</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822487</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822536</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822249</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822378</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821943</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822065</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821359</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131821408</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131820054</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131820189</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131818762</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131819767</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_CDS_GENOME-START>131819643</MEMBER_CDS_GENOME-START>
        <MEMBER_CDS_GENOME-END>131825170</MEMBER_CDS_GENOME-END>
        <MEMBER_CDS_CDNA-START>204</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>1181</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000321426</MEMBER_H-INVITATIONAL-ID>
        <MEMBER_H-INVITATIONAL-ID-VERSION>HIT000321426.15</MEMBER_H-INVITATIONAL-ID-VERSION>
        <MEMBER_ACCESSION-NO>X14454</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>X14454.1</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HUM</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID>HIP000084307</MEMBER_H-INVITATIONAL-PROTEIN-ID>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000084307.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Auto-annotated</MEMBER_CURATION-STATUS>
        <MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>P10914</MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>
        <MEMBER_DATA-SOURCE_IDENTITY>100.0</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>100.0</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Identical to known human protein(Category I).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
        </HGNC>
        <MEMBER_DB-REFERENCE_ENTREZGENE>3659</MEMBER_DB-REFERENCE_ENTREZGENE>
        <MEMBER_GENOME_START>131818780</MEMBER_GENOME_START>
        <MEMBER_GENOME_END>131826427</MEMBER_GENOME_END>
        <MEMBER_LOCUS_START>42649</MEMBER_LOCUS_START>
        <MEMBER_LOCUS_END>50296</MEMBER_LOCUS_END>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>192</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>193</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>284</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>285</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>384</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>385</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>561</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>562</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>611</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>612</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>741</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>742</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>864</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>865</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>914</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>915</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>1050</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1051</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>2035</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131826237</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131826427</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131825084</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131825175</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131823618</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822646</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822822</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822487</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821359</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131821408</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131820054</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131820189</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131818780</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131819767</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_CDS_GENOME-START>131819643</MEMBER_CDS_GENOME-START>
        <MEMBER_CDS_GENOME-END>131825170</MEMBER_CDS_GENOME-END>
        <MEMBER_CDS_CDNA-START>198</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>1175</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000432891</MEMBER_H-INVITATIONAL-ID>
        <MEMBER_H-INVITATIONAL-ID-VERSION>HIT000432891.7</MEMBER_H-INVITATIONAL-ID-VERSION>
        <MEMBER_ACCESSION-NO>AK314025</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>AK314025.1</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HTC</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID>HIP000084307</MEMBER_H-INVITATIONAL-PROTEIN-ID>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000084307.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Auto-annotated</MEMBER_CURATION-STATUS>
        <MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>P10914</MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>
        <MEMBER_DATA-SOURCE_IDENTITY>100.0</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>100.0</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Identical to known human protein(Category I).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
        </HGNC>
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      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
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        <DIVISION>HUM</DIVISION>
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        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
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        <HGNC>
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        </HGNC>
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        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
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        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>668</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>717</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>718</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>853</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>854</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>975</MEMBER_EXON-CDNA_END>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822487</MEMBER_EXON-GENOME_START>
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        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822249</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822378</MEMBER_EXON-GENOME_END>
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        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821943</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822065</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821359</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131821408</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131820054</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131820189</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131819646</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131819767</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_CDS_GENOME-START>131819646</MEMBER_CDS_GENOME-START>
        <MEMBER_CDS_GENOME-END>131825170</MEMBER_CDS_GENOME-END>
        <MEMBER_CDS_CDNA-START>1</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>975</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000242270</MEMBER_H-INVITATIONAL-ID>
        <MEMBER_H-INVITATIONAL-ID-VERSION>HIT000242270.13</MEMBER_H-INVITATIONAL-ID-VERSION>
        <MEMBER_ACCESSION-NO>AB103081</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>AB103081.1</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HUM</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID>HIP000084308</MEMBER_H-INVITATIONAL-PROTEIN-ID>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000084308.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Auto-annotated</MEMBER_CURATION-STATUS>
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        <MEMBER_DATA-SOURCE_IDENTITY>97.561</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>75.69</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Similar to Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Similar to known protein(Category II).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
        </HGNC>
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        <MEMBER_GENOME_END>131825170</MEMBER_GENOME_END>
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        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1</MEMBER_EXON-CDNA_START>
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        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>88</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>187</MEMBER_EXON-CDNA_END>
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        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>188</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>364</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>365</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>414</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>415</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>544</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>545</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>667</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>668</MEMBER_EXON-CDNA_START>
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        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131825084</MEMBER_EXON-GENOME_START>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_EXON-GENOME>
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          <MEMBER_EXON-GENOME_END>131822822</MEMBER_EXON-GENOME_END>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_EXON-GENOME>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131821943</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131822065</MEMBER_EXON-GENOME_END>
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        <MEMBER_EXON-GENOME>
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        <MEMBER_CDS_GENOME-START>131821323</MEMBER_CDS_GENOME-START>
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        <MEMBER_CDS_CDNA-START>1</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>753</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000493394</MEMBER_H-INVITATIONAL-ID>
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        <MEMBER_ACCESSION-NO>AK298770</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>AK298770.1</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HUM</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
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        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000359595.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Auto-annotated</MEMBER_CURATION-STATUS>
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        <MEMBER_DATA-SOURCE_IDENTITY>100.0</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>36.62</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Similar to Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Similar to known protein(Category II).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
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          <MEMBER_EXON-CDNA_START>1</MEMBER_EXON-CDNA_START>
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        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
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        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>457</MEMBER_EXON-CDNA_START>
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        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>587</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>706</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>707</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>935</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131826237</MEMBER_EXON-GENOME_START>
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        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822646</MEMBER_EXON-GENOME_START>
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        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822487</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131822249</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131785239</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131776132</MEMBER_EXON-GENOME_START>
          <MEMBER_EXON-GENOME_END>131776360</MEMBER_EXON-GENOME_END>
        </MEMBER_EXON-GENOME>
        <MEMBER_CDS_GENOME-START>131785312</MEMBER_CDS_GENOME-START>
        <MEMBER_CDS_GENOME-END>131826465</MEMBER_CDS_GENOME-END>
        <MEMBER_CDS_CDNA-START>1</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>633</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
      <MAPPED_MEMBER>
        <MEMBER_H-INVITATIONAL-ID>HIT000329559</MEMBER_H-INVITATIONAL-ID>
        <MEMBER_H-INVITATIONAL-ID-VERSION>HIT000329559.12</MEMBER_H-INVITATIONAL-ID-VERSION>
        <MEMBER_ACCESSION-NO>AB209624</MEMBER_ACCESSION-NO>
        <MEMBER_ACCESSION-NO-VERSION>AB209624.1</MEMBER_ACCESSION-NO-VERSION>
        <DIVISION>HUM</DIVISION>
        <MOL-TYPE>mRNA</MOL-TYPE>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID>HIP000155018</MEMBER_H-INVITATIONAL-PROTEIN-ID>
        <MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>HIP000155018.1</MEMBER_H-INVITATIONAL-PROTEIN-ID-VERSION>
        <MEMBER_CODING-POTENTIAL>Protein coding</MEMBER_CODING-POTENTIAL>
        <MEMBER_CURATION-STATUS>Auto-annotated</MEMBER_CURATION-STATUS>
        <MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>P10914</MEMBER_DATA-SOURCE_DB-REFERENCE_PROTEIN-MOTIF-ID>
        <MEMBER_DATA-SOURCE_IDENTITY>100.0</MEMBER_DATA-SOURCE_IDENTITY>
        <MEMBER_DATA-SOURCE_COVERAGE>12.62</MEMBER_DATA-SOURCE_COVERAGE>
        <MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>Homo sapiens (Human).</MEMBER_DATA-SOURCE_HOMOLOGOUS_SPECIES>
        <MEMBER_DEFINITION>Similar to Interferon regulatory factor 1; IRF-1;</MEMBER_DEFINITION>
        <MEMBER_SIMILARITY-CATEGORY>Similar to known protein(Category II).</MEMBER_SIMILARITY-CATEGORY>
        <MEMBER_EXP-EVIDENCE>Protein evidence</MEMBER_EXP-EVIDENCE>
        <MEMBER_EXP-CODE>1</MEMBER_EXP-CODE>
        <HGNC>
          <GENE-NAME_GENEW>IRF1</GENE-NAME_GENEW>
          <APPROVED-NAME_GENEW>interferon regulatory factor 1</APPROVED-NAME_GENEW>
        </HGNC>
        <MEMBER_DB-REFERENCE_ENTREZGENE>3659</MEMBER_DB-REFERENCE_ENTREZGENE>
        <MEMBER_GENOME_START>131818777</MEMBER_GENOME_START>
        <MEMBER_GENOME_END>131824724</MEMBER_GENOME_END>
        <MEMBER_LOCUS_START>42646</MEMBER_LOCUS_START>
        <MEMBER_LOCUS_END>48593</MEMBER_LOCUS_END>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>1107</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-CDNA>
          <MEMBER_EXON-CDNA_START>1108</MEMBER_EXON-CDNA_START>
          <MEMBER_EXON-CDNA_END>5152</MEMBER_EXON-CDNA_END>
        </MEMBER_EXON-CDNA>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131823618</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_EXON-GENOME>
          <MEMBER_EXON-GENOME_START>131818777</MEMBER_EXON-GENOME_START>
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        </MEMBER_EXON-GENOME>
        <MEMBER_CDS_GENOME-START>131821866</MEMBER_CDS_GENOME-START>
        <MEMBER_CDS_GENOME-END>131822555</MEMBER_CDS_GENOME-END>
        <MEMBER_CDS_CDNA-START>1375</MEMBER_CDS_CDNA-START>
        <MEMBER_CDS_CDNA-END>2064</MEMBER_CDS_CDNA-END>
      </MAPPED_MEMBER>
    </MAPPED>
    <PATHOLOGY>
      <PATHOLOGY_DATE-LAST-UPDATE>27-May-2015</PATHOLOGY_DATE-LAST-UPDATE>
      <PATHOLOGY_DATE-LAST-MODIFIED>27-May-2015</PATHOLOGY_DATE-LAST-MODIFIED>
      <PATHOLOGY_DISEASE-RELEASE>9.0</PATHOLOGY_DISEASE-RELEASE>
      <KNOWN-DISEASE-GENE>
        <CDNA-OMIM_DB-REFERENCE_OMIM-DISEASE>137215</CDNA-OMIM_DB-REFERENCE_OMIM-DISEASE>
        <CDNA-OMIM_DISEASE_DISEASE-NAME>Gastric cancer</CDNA-OMIM_DISEASE_DISEASE-NAME>
        <CDNA-OMIM_DB-REFERENCE_OMIM-DISEASE>153550</CDNA-OMIM_DB-REFERENCE_OMIM-DISEASE>
        <CDNA-OMIM_DISEASE_DISEASE-NAME>Macrocytic anemia, refractory, of 5q- syndrome</CDNA-OMIM_DISEASE_DISEASE-NAME>
        <CDNA-OMIM_DISEASE-RELATION>Myelodysplastic syndrome, preleukemic</CDNA-OMIM_DISEASE-RELATION>
        <CDNA-OMIM_DISEASE-RELATION>Myelogenous leukemia, acute</CDNA-OMIM_DISEASE-RELATION>
        <CDNA-OMIM_DISEASE-RELATION>Nonsmall cell lung cancer</CDNA-OMIM_DISEASE-RELATION>
        <CDNA-OMIM_DB-REFERENCE_OMIM>147575</CDNA-OMIM_DB-REFERENCE_OMIM>
        <CDNA-OMIM_MORBID-MAP_OMIM-TITLE>INTERFERON REGULATORY FACTOR 1</CDNA-OMIM_MORBID-MAP_OMIM-TITLE>
      </KNOWN-DISEASE-GENE>
    </PATHOLOGY>
  </LOCUSXML>
</H-Inv>