H-InvDB x AHG DB
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H-InvDB_8.3 released on March 26, 2013.
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H-Inv cluster ID: HIX0005159 Created date: 26-Mar-2013 Last modified: 26-Mar-2013
Definition: Interferon regulatory factor 1.
 
 

Gene structure  G-integra H-DBAS
H-Inv cluster ID HIX0005159
Genomic location  G-integra Help Chromosome 5
Location 5q31.1
Position 131776132- 131826469
Strand -
Antisense cluster ID(s) NA
Database links RefSeq NM_002198
Ensembl ENST00000437654ENST00000439555ENST00000472045ENST00000463784ENST00000458069ENST00000245414ENST00000459982ENST00000493208ENST00000405885ENST00000476613
Entrez Gene Entrez Gene ID:3659
KEGG GENES KEGG GENES(3659)
GeneCard GeneCardIRF1*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Cluster member H-Inv ID(s) HIT000034397HIT000321426HIT000274032HIT000432891HIT000266641HIT000266642HIT000268586HIT000242270HIT000493394HIT000329559HIT000305775
Additional cluster member candidate(s) NA
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment
Mini-G Locus map Locus map

 
TOP 1-10 11-11 LAST 
Cluster member (s)  G-integra H-DBAS
Locus member number 1
H-Inv ID Transcript viewHIT000034397
Accession number BC009483.2
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131818780- 131826434
Strand -
Gene structure 10 exons
 
TOP 1-10 11-11 LAST 
Locus member number 2
H-Inv ID Transcript viewHIT000321426
Accession number X14454.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131818780- 131826427
Strand -
Gene structure 10 exons
 
TOP 1-10 11-11 LAST 
Locus member number 3
H-Inv ID Transcript viewHIT000274032
Accession number CR594837.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131818814- 131826453
Strand -
Gene structure 10 exons
 
TOP 1-10 11-11 LAST 
Locus member number 4
H-Inv ID Transcript viewHIT000432891
Accession number AK314025.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131819643- 131826465
Strand -
Gene structure 10 exons
 
TOP 1-10 11-11 LAST 
Locus member number 5
H-Inv ID Transcript viewHIT000266641
Accession number BT019755.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131819643- 131825170
Strand -
Gene structure 9 exons
 
TOP 1-10 11-11 LAST 
Locus member number 6
H-Inv ID Transcript viewHIT000266642
Accession number BT019756.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131819643- 131825170
Strand -
Gene structure 9 exons
 
TOP 1-10 11-11 LAST 
Locus member number 7
H-Inv ID Transcript viewHIT000268586
Accession number CR541713.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131819646- 131825170
Strand -
Gene structure 9 exons
 
TOP 1-10 11-11 LAST 
Locus member number 8
H-Inv ID Transcript viewHIT000242270
Accession number AB103081.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Interferon regulatory factor 1; IRF-1;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P10914)  [Identity/coverage = 97.561%/75.69%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131821323- 131825170
Strand -
Gene structure 7 exons
 
TOP 1-10 11-11 LAST 
Locus member number 9
H-Inv ID Transcript viewHIT000493394
Accession number AK298770.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Interferon regulatory factor 1; IRF-1;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P10914)  [Identity/coverage = 100.0%/36.62%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131776132- 131826465
Strand -
Gene structure 6 exons
 
TOP 1-10 11-11 LAST 
Locus member number 10
H-Inv ID Transcript viewHIT000329559
Accession number AB209624.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Interferon regulatory factor 1; IRF-1;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P10914)  [Identity/coverage = 98.98%/60.31%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131818777- 131824724
Strand -
Gene structure 5 exons
 
TOP 1-10 11-11 LAST 
Locus member number 11
H-Inv ID Transcript viewHIT000305775
Accession number CR626580.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Hypothetical short protein.
Similarity category  Help Category: Hypothetical short protein(Category VI).
Hypothetical short protein.
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q31.1
Position 131818775- 131819387
Strand -
Gene structure 1 exons

Alternative splicing (AS) information  G-integra H-DBAS
Pattern of alternative splicing isoforms 5' terminal AS;  3' terminal AS;  Internal AS; 
Position of alternative splicing isoforms Cassette;  Internal acceptor site;  Retained intron; 
Alternative splicing isoform H-Inv ID(s) Splicing isoformHIT000493394Splicing isoformHIT000329559Splicing isoformHIT000034397
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment

Gene function information  G-integra PPI viewer H-DBAS Gene family Similarity Search Tool TACT
H-Inv cluster ID HIX0005159
Representative H-Inv ID Representative H-Inv IDHIT000034397
Accession number BC009483.2
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Interferon regulatory factor 1.
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (NP_002189)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol IRF1 
HGNC aliases NA
HGNC name interferon regulatory factor 1 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000084307
No. of interaction 12
Interaction partner(s) HIP000022609HIP000025414HIP000026075HIP000037612HIP000039881HIP000051820HIP000088757HIP000096721HIP000096938HIP000097433HIP000100966HIP000101884
BIND NA
DIP 115228E;  88067E;  88068E; 
MINT NA
HPRD 01238;  01241;  02777;  02829;  02867;  03336;  03554;  04078;  06780;  07223;  10556; 
IntAct EBI-3931236;  EBI-1067616;  EBI-3906874; 
Database links RefSeq NM_002198
Ensembl ENST00000437654ENST00000439555ENST00000472045ENST00000463784ENST00000458069ENST00000245414ENST00000459982ENST00000493208ENST00000405885ENST00000476613
Entrez Gene Entrez Gene ID:3659
KEGG GENES KEGG GENES(3659)
GeneCard GeneCardIRF1*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Related H-InvDB links G-integraG-integra PPI viewerPPI view H-DBASH-DBAS Gene familyGene family;  Similarity Search ToolSimilarity search tool TACTTACT
Gene expression information   H-ANGEL DNAProbeLocator Last modified:26-Mar-2013
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene AGhsA220418; 
Affymetrix
GeneChip
HG-Focus 202531_at; 
HG-U133 202531_at; 
HG-U133A 202531_at; 
HG-U133A_2 202531_at; 
HG-U133B NA
HG-U133_Plus_2 202531_at; 
HG-U95 669_s_at; 
HG-U95A 669_s_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2828595;  2875350;  2875351;  2875353;  2875356;  2875358;  2875360;  2875362;  2875363;  2875364;  2875365;  2875366;  2875372;  2875375; 
HuGeneFL L05072_s_at; 
Agilent Human 1A Oligo Microarray:PGID215 A_23_P41765; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P41765; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:26-Mar-2013
Disease relation Disease name: Gastric cancer (137215);  Disease name: Macrocytic anemia, refractory, of 5q- syndrome (153550); 
Related information in OMIM OMIM ID:  147575;  Title: INTERFERON REGULATORY FACTOR 1
Co-localized orphan diseases OMIM ID:  131400147061181460248310605598605845606070606263606348608174608970609657609754610535612599
Disease related mutation MutationView:  147575
JRE-1.4.0 or later is required.Download JRE at Sun's web site.
Co-occurred words and phrases with this gene name in PubMed (LEGENDA) LEGENDA Gene name Entrez Gene ID:(3659); 
Disease Entrez Gene ID:(3659); 
Gene function Entrez Gene ID:(3659); 
Substance Entrez Gene ID:(3659); 
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo ViewerLEGENDALEGENDA