H-InvDB_8.3 released on March 26, 2013. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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H-Inv ID Program Identity E-Value Organism HIT000192814 FASTY 34t22b3 NCBI-BLASTX 2.2.9 =75% =50% =25% all 0 0-10 -5 -10 -20 -30 -40 all Homo sapiens Vertebrate ( non Homo sapiens ) Eukaryote ( non Vertebrate ) Bacteria & Virus Others FASTY 34t22b3   A.A. Length Identity(%) Score E-Value Species Description P17290 444 98.6 3502.2 5.8e-187 Verteb Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). Q86Y20 163 98.2 1278.7 4.1e-63 Hom Tryptophan hydroxylase (Fragment). Q8HXR0 83 96.4 624.0 1.2e-26 Verteb Tryptophan hydroxylase (Fragment). P17752 444 95.9 3441.2 1.5e-183 Hom Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). NP_004170 444 95.9 3441.2 1.5e-183 Hom Tryptophan hydroxylase 1. Q86WC5 74 95.9 572.2 9.3e-24 Hom Tryptophan hydroxylase (Fragment). P17752-2 466 95.9 3389.4 1.1e-180 Hom Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). Isoform 2. Q86Y19 206 93.7 1582.2 5.1e-80 Hom Tryptophan hydroxylase (Fragment). A0JL57 42 90.5 308.0 4.8e-09 Verteb Tryptophan hydroxylase 2 (Fragment). P09810 444 89.4 3268.9 5.8e-174 Verteb Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). P17532 447 87.5 3205.4 2e-170 Verteb Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). Q3UK52 447 87.5 3205.4 2e-170 Verteb TIB-55 BB88 cDNA, RIKEN full-length enriched library, clone:I730028N07 product:tryptophan hydroxylase 1, full insert sequence (TIB-55 BB88 cDNA, RIKEN full-length enriched library, clone:I730008K11 product:tryptophan hydroxylase 1, full insert sequence). Q8K3R1 446 86.4 3134.8 1.7e-166 Verteb Tryptophane hydroxylase. Q2LDD4 161 85.1 1187.9 4.7e-58 Verteb Tryptophan hydroxylase (Fragment). P70080 445 85.1 3139.6 9.1e-167 Verteb Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1). A0JL56 45 84.4 361.4 5.1e-12 Verteb Tryptophan hydroxylase 2 (Fragment). A0JL58 32 84.4 246.5 1.3e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A8CW11 238 82.4 1668.6 7.9e-85 Verteb Tryptophan hydroxylase 2 (Fragment). Q92142 481 82.3 3054.2 5.3e-162 Verteb Tryptophan 5-hydroxylase (EC 1.14.16.4) (Tryptophan 5-monooxygenase). Q9JHZ8 195 81.5 1239.2 6.5e-61 Verteb Tryptophan hydroxylase (Fragment). A4UU60 178 81.5 1218.3 9.6e-60 Verteb Tryptophan hydroxylase 1 (Fragment). A7U671 169 79.8 1207.9 3.6e-59 Verteb Tryptophan hydroxylase 2 (Fragment). Q8AY71 471 79.4 2827.0 2.4e-149 Verteb Tryptophan hydroxylase D1. Q460J4 45 78.6 276.4 2.8e-07 Eukar Tyrosine hydroxylase (Fragment). Q460I2 45 78.6 276.4 2.8e-07 Eukar Tyrosine hydroxylase (Fragment). Q6PBX4 483 78.4 2928.5 5.3e-155 Verteb Tph1 protein. Q3TZH2 155 77.7 874.6 1.3e-40 Verteb Bone marrow mast cells cDNA, RIKEN full-length enriched library, clone:K1C0015E11 product:tryptophan hydroxylase 1, full insert sequence. Q6IWN2 479 77.3 2855.6 6.1e-151 Verteb Non-neuronal tryptophan hydroxylase 1. A2VCX5 480 76.6 2786.2 4.5e-147 Verteb Tryptophan hydroxylase 1, like. Q6IWP4 480 76.6 2786.2 4.5e-147 Verteb Tryptophan hydroxylase D2 (Tph1l protein). Q4JLA4 274 74.5 1601.8 4.1e-81 Verteb Neuronal tryptophan hydroxylase (Fragment). Q6PKI7 489 73.6 2747.7 6.2e-145 Verteb Neuronal tryptophan hydroxylase. Q6QE16 75 73.3 499.1 1.1e-19 Verteb Tyrosine hydrolase (Fragment). Q8CGU9 485 72.8 2723.9 1.3e-143 Verteb Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase). Q4T586 500 72.4 2600.4 9.9e-137 Verteb Chromosome 13 SCAF9358, whole genome shotgun sequence. Q8IWU9 490 71.9 2696.3 4.5e-142 Hom Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase). NP_775489 490 71.9 2696.3 4.5e-142 Hom Tryptophan hydroxylase 2. Q14CC5 496 71.9 2696.2 4.6e-142 Hom TPH2 protein. Q6IWN1 486 71.9 2558.7 2.1e-134 Verteb Neuronal tryptophan hydroxylase 2. Q0VBT4 488 71.7 2701.1 2.4e-142 Verteb Tryptophan hydroxylase 2. Q2HZ26 490 71.7 2689.1 1.1e-141 Verteb Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2). Q14CB0 490 71.7 2693.9 6.2e-142 Hom Tryptophan hydroxylase 2. Q0EAB8 491 71.6 2701.0 2.5e-142 Verteb Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2). Q8CGV2 488 71.5 2685.5 1.8e-141 Verteb Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase). Q08EN2 206 70.2 1181.4 1.1e-57 Hom TPH1 protein. A0JL55 65 69.2 429.5 8.3e-16 Verteb Tryptophan hydroxylase 2 (Fragment). Q1LUE3 473 68.6 2267.0 3.7e-118 Verteb Tryptophan hydroxylase 2 (Tryptophan 5-monooxygenase). Q6IWP5 500 68.6 2266.6 3.9e-118 Verteb Tryptophan hydroxylase 2. Q1LUE4 500 68.6 2266.6 3.9e-118 Verteb Tryptophan hydroxylase 2 (Tryptophan 5-monooxygenase). Q75V71 473 67.3 2207.1 8e-115 Verteb Tryptophan hydroxylase R. A0JL59 102 66.3 528.1 2.7e-21 Verteb Tryptophan hydroxylase 2 (Fragment). Q8MJD2 198 66.2 1097.9 4.8e-53 Verteb Tyrosine hydroxylase (Fragment). Q800U6 124 65.9 697.9 9.3e-31 Verteb Tyrosine hydroxylase (Fragment). Q6VAC0 150 64.7 864.1 5.1e-40 Verteb Neuronal tryptophan hydroxylase (Fragment). Q38J76 169 64.3 949.4 9e-45 Verteb Tyrosine hydroxylase (EC 1.14.16.2) (Fragment). Q1PPW9 212 64.2 1169.3 5.2e-57 Verteb Tyrosine hydroxylase (Fragment). A1XP44 523 64.2 2286.6 3e-119 Eukar Tryptophan 5-monoxygenase. Q9NJQ3 239 63.9 1302.4 2e-64 Eukar Tryptophan hydroxylase (Fragment). Q8IZE1 44 63.6 256.3 3.7e-06 Hom Truncated tyrosine hydroxylase (Fragment). Q8N1X9 250 61.9 837.9 1.5e-38 Hom cDNA FLJ37295 fis, clone BRAMY2015311, moderately similar to TRYPTOPHAN 5-MONOOXYGENASE (EC 1.14.16.4). Q7Q665 531 61.2 1992.2 7.5e-103 Eukar AGAP006020-PA. P97517 102 60.8 491.0 3.1e-19 Verteb Tyrosine hydroxylase (Fragment). Q76CT5 479 60.7 2028.8 6.9e-105 Eukar Tryptophan 5-hydroxylase. Q8HXJ0 200 60.1 755.7 5.6e-34 Verteb Putative uncharacterized protein. B0XK29 547 59.9 1969.2 1.4e-101 Eukar Putative uncharacterized protein. A0MM58 102 59.8 488.6 4.2e-19 Verteb Tyrosine hydroxylase (Fragment). Q4THP6 218 59.0 604.3 1.5e-25 Verteb Chromosome undetermined SCAF2776, whole genome shotgun sequence. (Fragment). A0JL53 95 58.9 493.9 2.1e-19 Verteb Tryptophan hydroxylase 2 (Fragment). Q7SYH6 449 58.5 2028.0 7.6e-105 Verteb Pah (Phenylalanine hydroxylase). Q6IVY7 454 58.5 1998.0 3.5e-103 Verteb Phenylalanine hydroxylase. Q6PHI7 449 58.3 2022.0 1.6e-104 Verteb Phenylalanine hydroxylase. A8XGU6 526 58.2 1267.2 1.8e-62 Eukar CBR-TPH-1 protein. Q4S5C2 458 58.0 1986.0 1.7e-102 Verteb Chromosome 19 SCAF14731, whole genome shotgun sequence. A7VKD9 546 58.0 2053.0 3.1e-106 Eukar Tryptophan hydroxylase. Q9W0K2 555 57.7 1934.4 1.2e-99 Eukar CG9122-PA (EC 1.14.16.1) (EC 1.14.16.4) (GH12537p). A6YIC4 456 57.3 1923.8 4.8e-99 Eukar Tryptophan hydroxylase. Q5RDX0 295 57.3 1321.3 1.7e-65 Verteb Putative uncharacterized protein DKFZp469G0337. Q7Q6R7 428 56.9 1968.5 1.6e-101 Eukar AGAP005712-PC. A7UTU7 447 56.9 1968.2 1.6e-101 Eukar AGAP005712-PA. Q7PIP2 448 56.9 1968.2 1.6e-101 Eukar AGAP005712-PB. A7SX22 401 56.6 1687.8 6.8e-86 Eukar Predicted protein. A9L956 334 56.5 1629.2 1.2e-82 Verteb Tyrosine hydroxylase, isoform 2 (Predicted) (Fragment). Q6PKI8 446 56.2 1981.4 3e-102 Verteb Phenylalanine hydroxylase. Q29DP1 570 56.2 1897.2 1.5e-97 Eukar GA21560-PA (Fragment). Q4VBE2 445 56.0 1957.5 6.4e-101 Verteb Putative uncharacterized protein mgc108157. O96947 450 55.6 1876.0 2.2e-96 Eukar Phenylalanine hydroxylase. Q2KIH7 451 55.4 1895.2 1.9e-97 Verteb Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase). Q6AYW2 453 55.2 1903.5 6.5e-98 Verteb Phenylalanine hydroxylase. P16331 453 55.1 1914.3 1.6e-98 Verteb Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase). Q91WV1 453 55.1 1909.5 3e-98 Verteb Phenylalanine hydroxylase. Q3UEH8 452 55.1 1890.4 3.5e-97 Verteb Adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730029F16 product:phenylalanine hydroxylase, full insert sequence. B0W3Y2 428 54.9 1956.6 7.2e-101 Eukar Phenylalanine-4-hydroxylase. Q95LQ6 250 54.9 1117.9 3.8e-54 Verteb Tyrosine hydroxylase (EC 1.14.16.2) (Fragment). P04176 453 54.9 1903.5 6.5e-98 Verteb Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase). Q5MR21 456 54.9 1926.2 3.5e-99 Eukar Phenylalanine hydroxylase (EC 1.14.16.1). Q8I901 447 54.7 1932.3 1.6e-99 Eukar Phenylalanine hydroxylase (EC 1.14.16.1). A2V6X7 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X2 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X6 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X4 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X1 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X3 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X8 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X5 57 54.7 248.5 1e-05 Verteb Tryptophan hydroxylase 2 (Fragment). A2V6X0 57 54.7 247.3 1.2e-05 Verteb Tryptophan hydroxylase 2 (Fragment). P00439 452 54.4 1902.3 7.6e-98 Hom Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase). NP_000268 452 54.4 1902.3 7.6e-98 Hom Phenylalanine hydroxylase. Q8TEY0 452 54.2 1897.6 1.4e-97 Hom Phenylalanine hydroxylase. O17498 438 53.9 1841.5 1.8e-94 Eukar Phenylalanine hydroxylase (EC 1.14.16.1) (Fragment). O96370 497 53.7 1837.1 3.3e-94 Eukar Tryptophan hydroxylase (EC 1.14.16.4). Q4JLW0 273 53.6 1183.1 8.8e-58 Verteb Tyrosine hydroxylase (Fragment). Q29EN8 452 53.6 1848.5 7.6e-95 Eukar GA20325-PA (Fragment). Q59E23 447 53.6 1843.8 1.4e-94 Eukar CG7399-PB, isoform B (EC 1.14.16.1) (EC 1.14.16.4). P17276 452 53.6 1843.7 1.4e-94 Eukar Protein henna [Includes: Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4-monooxygenase); Tryptophan 5-monooxygenase (EC 1.14.16.4) (TRH) (Tryptophan 5-hydroxylase)]. A8CW12 332 53.5 1439.0 4.9e-72 Verteb Tyrosine hydroxylase (Fragment). Q2V0P9 457 53.3 1892.7 2.6e-97 Eukar Phenylalanine hydroxylase. A1Y9J6 448 52.9 1780.4 4.7e-91 Eukar Tryptophan hydroxylase. Q5K185 82 52.9 226.9 0.00016 Eukar Pale protein (Fragment). Q6ZM47 408 52.7 1492.6 5e-75 Verteb Tyrosine hydroxylase (Fragment). Q5DGG4 497 52.7 1800.0 3.8e-92 Eukar SJCHGC01235 protein. Q3UTB3 403 52.5 1657.8 3.1e-84 Verteb 2 cells egg cDNA, RIKEN full-length enriched library, clone:B020005C09 product:tyrosine hydroxylase, full insert sequence. B0VXL5 188 52.4 754.9 6.2e-34 Verteb Tyrosine hydroxylase isoform D2,8,9 (Predicted) (Fragment). Q5RHI3 475 52.4 1726.1 5e-88 Verteb Novel protein similar to tyrosine hydroxylase (Th) (Fragment). Q1LWZ5 471 52.2 1686.7 7.8e-86 Verteb Tyrosine hydroxylase 2. Q6IVB6 471 52.2 1684.3 1.1e-85 Verteb Tyrosine hydroxylase 2. Q5PY00 472 51.9 1687.9 6.7e-86 Verteb Tyrosine hydroxylase 2 (EC 1.14.16.2). B0LQU2 467 51.8 1273.9 7.6e-63 Eukar Henna mutant bp (EC 1.14.16.1). A1KXR0 489 51.8 1712.8 2.7e-87 Verteb Tyrosine hydroxylase. A8WSM6 457 51.4 1837.7 3e-94 Eukar CBR-PAH-1 protein (Fragment). P11982 491 51.4 1693.6 3.2e-86 Verteb Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). Q9PU40 491 51.4 1681.6 1.5e-85 Verteb Tyrosine hydroxylase. Q8MIU1 171 51.2 724.4 3.1e-32 Verteb Tyrosine hydroxylase (Fragment). P24529 498 51.2 1689.9 5.2e-86 Verteb Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). P04177 498 51.2 1688.7 6e-86 Verteb Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). Q2V4U7 429 51.0 1276.9 5.2e-63 Eukar Tryptophan hydroxylase protein 1, isoform b. Q9XZD1 532 51.0 1275.5 6.3e-63 Eukar Tryptophan hydroxylase (Tryptophan hydroxylase protein 1, isoform a). A9UUJ8 428 50.9 1775.9 8.4e-91 Eukar Predicted protein. A0JGX6 489 50.9 1650.5 8e-84 Verteb Tyrosine 3-monooxygenase. P90925 457 50.8 1808.9 1.2e-92 Eukar Probable phenylalanine-4-hydroxylase 1 (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase) (Biogenic amine synthesis protein 2). Q6IVY6 476 50.7 1702.2 1.1e-86 Verteb Tyrosine hydroxylase 2. Q6XJ04 212 50.3 679.9 9.3e-30 Eukar Similar to Drosophila melanogaster Hn (Fragment). Q9XYQ5 457 50.2 1775.4 8.9e-91 Eukar Phenylalanine hydroxylase (EC 1.14.16.1). O42091 488 50.2 1630.2 1.1e-82 Verteb Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). O42428 489 50.0 1645.8 1.5e-83 Verteb Tyrosine hydroxylase 1 (EC 1.14.16.2). Number of sequences: 144