Description: Immunoglobulin (Ig) is essential for the immune responses, and expressed at the surface of the B cells or secreted by the plasma cells. Ig is composed of the polypeptide chains with two different characters: heavy and light chains (κ,λ).
H-InvDB Ig annotation dataset was intended to include the genes of heavy and light chains (κ,λ). Ig-like genes and non-Ig genes (ex. VpreB, T-cell receptor) were excluded. The H-InvDB Ig dataset was defined by genomic location obtained from literature, sequence similarity search using a standard protein dataset, keyword search against sequence description and manual curation.