bases per tick :
500
200
100
50
20
10
5
2
kb first site :
main :
All Human Genes
JIGSAW prediction
ESTs assembly
homology :
UCSC
CCDS
Pseudogene.org
Conserved regions (
Segmental duplication
P.troglodytes
P.abelii
M.mulatta
M.musculus
R.norvegicus
C.familiaris
E.caballus
B.taurus
M.domestica
G.gallus
D.rerio
O.latipes
T.nigroviridis
T.rubripes
)
gene prediction :
FGENESH
GenScan
HMMgene
tRNA
show... :
SNPs
ESTs(summary)
ESTs(detail)
CAGE tag(summary)
CAGE tag(detail)
sequence viewer :
( start, end )
( middle, total length )
= (
,
)
HIX0208233
HIT000618887 (
ENST00000519537
)
Representative transcript
(Conserved hypothetical protein.)
genome : 39,424,224 - 39,437,653 (13,430)
query : 1 - 506 (506/506)
4 exons
identity = 1.000
5'(1.000)3'
coverage = 1.000
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 16, cyto 15
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0208233)
HIX0208233
HIT000622801 (
ENST00000523523
)
(Hypothetical short protein.)
genome : 39,433,113 - 39,437,653 (4,541)
query : 1 - 273 (273/273)
3 exons
identity = 1.000
5'(1.000;1.000)3'
coverage = 1.000
SOSUI :
SOLUBLE PROTEIN
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0208233)
HIX0034291
HIT000619347 (
ENST00000520001
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,008 - 39,468,263 (26,256)
query : 1 - 728 (728/728)
7 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
cyto 13.5, cyto_nucl 13, nucl 7.5, extr 4, cysk 3,
golg 3
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000204628 (
NM_014237
)
(Disintegrin and metalloproteinase domain-containing protein 18 isoform 1 preproprotein.)
genome : 39,442,087 - 39,587,583 (145,497)
query : 1 - 2,399 (2,399/2,399)
20 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 6, plas 5, cyto 5, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
RefSeq
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000655716 (
NM_001190956
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,087 - 39,469,094 (27,008)
query : 1 - 1,446 (1,446/1,462)
6 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 0.999
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
extr 12, cyto 8, cyto_nucl 8, nucl 6, extr_plas 6
RefSeq
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000432827
(
AK313961
)
Representative transcript
(Disintegrin and metalloproteinase domain-containing protein 18 isoform 1 preproprotein.)
genome : 39,442,097 - 39,587,459 (145,363)
query : 1 - 2,265 (2,265/2,265)
20 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 6, plas 5, cyto 5, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
Ortholog candidate ( ->
Evola
)
Mus
sp. (Mouse) : AK076633
Oryzias
sp. (Medaka) : ENSORLT00000020217
Pongo
sp. (Orangutan) : ENSPPYT00000021615
Monodelphis
sp. (Opossum) : XM_001381854
Equus
sp. (Horse) : XM_001915545
Gallus
sp. (Chicken) : XM_424396
Pan
sp. (Chimpanzee) : XM_519721
Bos
sp. (Cow) : XM_616382
Canis
sp. (Dog) : XM_844491
Macaca
sp. (Macaque) : XR_011335
Rattus
sp. (Rat) : Y11490
HIX0034291
HIT000109805 (
ENST00000265707
)
(Disintegrin and metalloproteinase domain-containing protein 18 isoform 1 preproprotein.)
genome : 39,442,100 - 39,587,583 (145,484)
query : 1 - 2,386 (2,386/2,386)
20 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 6, plas 5, cyto 5, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000252365
(
AY358321
)
(Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,100 - 39,587,583 (145,484)
query : 1 - 2,314 (2,314/2,314)
19 exons
identity = 0.999
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;0.988;1.000;1.000;1.000;0.995;1.000;
1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
plas 6, extr 6, extr_plas 6, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000361145 (
ENST00000379866
)
(Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,100 - 39,587,583 (145,484)
query : 1 - 2,314 (2,314/2,314)
19 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
plas 6, extr 6, extr_plas 6, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000620099 (
ENST00000520772
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,104 - 39,469,094 (26,991)
query : 1 - 1,429 (1,429/1,429)
6 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
extr 12, cyto 8, cyto_nucl 8, nucl 6, extr_plas 6
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000264237
(
BC070279
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,104 - 39,468,757 (26,654)
query : 1 - 1,092 (1,092/1,121)
6 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 0.999
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
extr 12, cyto 8, cyto_nucl 8, nucl 6, extr_plas 6
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000093511
(
BC034624
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,107 - 39,469,094 (26,988)
query : 1 - 1,427 (1,427/1,443)
6 exons
identity = 0.998
5'(1.000;1.000;1.000;1.000;1.000;0.997)3'
coverage = 0.999
SOSUI :
SOLUBLE PROTEIN
PSORT :
extr 12, cyto 8, cyto_nucl 8, nucl 6, extr_plas 6
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000244761
(
AJ133004
)
(Disintegrin and metalloproteinase domain-containing protein 18 isoform 1 preproprotein.)
genome : 39,442,142 - 39,587,487 (145,346)
query : 1 - 2,248 (2,248/2,248)
20 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;0.988;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 6, plas 5, cyto 5, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000388242
(
BC121045
)
(Disintegrin and metalloproteinase domain-containing protein 18 isoform 1 preproprotein.)
genome : 39,442,142 - 39,587,487 (145,346)
query : 1 - 2,248 (2,248/2,248)
20 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
MEMBRANE PROTEIN
PSORT :
extr 6, plas 5, cyto 5, mito_pero 5, cyto_plas 5,
mito 4.5, pero 4.5
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000388243
(
BC121046
)
(Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,142 - 39,587,487 (145,346)
query : 1 - 1,886 (1,886/1,886)
18 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
SOSUI :
MEMBRANE PROTEIN
PSORT :
cyto 20, plas 5, extr 2, nucl 2, E.R._mito 2
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000619432 (
ENST00000520087
)
(Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,142 - 39,587,487 (145,346)
query : 1 - 1,886 (1,886/1,886)
18 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
SOSUI :
MEMBRANE PROTEIN
PSORT :
cyto 20, plas 5, extr 2, nucl 2, E.R._mito 2
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000640156 (
ENST00000541111
)
(Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,142 - 39,587,487 (145,346)
query : 1 - 1,886 (1,886/1,886)
18 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
SOSUI :
MEMBRANE PROTEIN
PSORT :
cyto 20, plas 5, extr 2, nucl 2, E.R._mito 2
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000621500 (
ENST00000522198
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,149 - 39,587,584 (145,436)
query : 1 - 2,005 (2,005/2,005)
16 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000;1.000;1.000;1.000;1.000;1.000;
1.000;1.000)3'
coverage = 1.000
InterPro :
IPR001590 : Peptidase M12B, ADAM/reprolysin
IPR001762 : Blood coagulation inhibitor, Disintegrin
IPR002870 : Peptidase M12B, propeptide
IPR006586 : ADAM, cysteine-rich
IPR018358 : Disintegrin, conserved site
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
nucl 21, cyto_nucl 16.5, cyto 8
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000384874
(
AK225744
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,442,150 - 39,468,377 (26,228)
query : 1 - 666 (666/705)
6 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
cyto_nucl 10, nucl 9.5, cysk 8, cyto 7.5, extr 6
H-InvDB(Transcript view)
H-InvDB(Locus view)
DDBJ
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000619894 (
ENST00000520559
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,462,146 - 39,468,263 (6,118)
query : 1 - 538 (538/538)
5 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
InterPro :
IPR002870 : Peptidase M12B, propeptide
GO :
0004222 : Molecular Function : metalloendopeptidase activity
0006508 : Biological Process : proteolysis
0008270 : Molecular Function : zinc ion binding
SOSUI :
SOLUBLE PROTEIN
PSORT :
mito 26.5, mito_pero 14, extr 3
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000623027 (
ENST00000523755
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,542,649 - 39,587,581 (44,933)
query : 1 - 804 (804/804)
5 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000;1.000)3'
coverage = 1.000
SOSUI :
MEMBRANE PROTEIN
PSORT :
cyto 12, plas 10, mito 7
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
HIX0034291
HIT000623382 (
ENST00000524117
)
(Similar to Disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; tMDC III; Precursor;)
genome : 39,542,693 - 39,581,477 (38,785)
query : 1 - 646 (646/646)
4 exons
identity = 1.000
5'(1.000;1.000;1.000;1.000)3'
coverage = 1.000
SOSUI :
MEMBRANE PROTEIN
PSORT :
cyto 14, plas 7, mito 7, cyto_nucl 7, cyto_golg 7
Ensembl
cDNA-genome Alignment
cDNA Multiple Alignment
(HIX0034291)
AC109633.5
39434796-39547622 F -
NCBI
AC136365.5
39547623-39594795 F -
NCBI