Human (Full-length cDNA) vs Mouse (Full-length cDNA)

Chromosome HIX RASV pair HUGO Definition AS pattern
AS affecting function
Cassette

Internal acceptor

Internal donor

Mutually exclusive

Retained intron

Alternative first exon

Alternative last exon

5'-end AS

3'-end AS
chr1
HIX0000033
HIT000004283
HIT000428933
SSU72
SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC 3.1.3.16) (CTD phosphatase SSU72).
Similar to RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC 3.1.3.16) (CTD phosphatase SSU72).

3'-end AS

Protein motif
GO
chr1
HIX0000046
HIT000033619
HIT000489273
PRKCZ
PRKCZ
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).
Protein kinase C, zeta isoform 2.

Alternative first exon

GO
Subcellular localization signal
chr1
HIX0000133
HIT000042432
HIT000051312
KIAA2013
KIAA2013
Protein of unknown function DUF2152 region containing protein.
Similar to Alpha 1 type I collagen.

3'-end AS

chr1
HIX0000387
HIT000264085
HIT000266300
AK2
AK2
Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).
Adenylate kinase 2 isoform b.

3'-end AS

Protein motif
chr1
HIX0000387
HIT000264085
HIT000491487
AK2
AK2
Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).
Similar to Adenylate kinase 2 isoform b.

Internal acceptor

Protein motif
chr1
HIX0000467
HIT000036430
HIT000335233
CAP1
CAP1
Adenylyl cyclase-associated protein.
Adenylyl cyclase-associated protein.

Internal donor

chr1
HIX0000467
HIT000036430
HIT000492734
CAP1
CAP1
Adenylyl cyclase-associated protein.
Similar to Adenylyl cyclase-associated protein.

Internal acceptor

Internal donor

Subcellular localization signal
chr1
HIX0000493
HIT000082453
HIT000339040
LEPRE1
LEPRE1
Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).
Oxoglutarate and iron-dependent oxygenase domain containing protein.

Internal donor

chr1
HIX0000566
HIT000004924
HIT000033540
BEND5
BEND5
Conserved hypothetical protein.
BEN domain containing protein.

Internal acceptor

chr1
HIX0000572
HIT000056323
HIT000432262
EPS15
EPS15
Ubiquitin interacting motif conserved site containing protein.
Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

5'-end AS

GO
Subcellular localization signal
chr1
HIX0000615
HIT000262256
HIT000422271
SSBP3
SSBP3
Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).
Single stranded DNA binding protein 3 isoform c.

Cassette

Protein motif
chr1
HIX0000684
HIT000024240
HIT000038818
SERBP1
SERBP1
SERPINE1 mRNA binding protein 1 (PAI-1 mRNA-binding protein variant).
SERPINE1 mRNA binding protein 1 isoform 2.

Internal acceptor

Protein motif
chr1
HIX0000684
HIT000024240
HIT000040233
SERBP1
SERBP1
SERPINE1 mRNA binding protein 1 (PAI-1 mRNA-binding protein variant).
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA- binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1).

Internal acceptor

Protein motif
chr1
HIX0000684
HIT000024240
HIT000049877
SERBP1
SERBP1
SERPINE1 mRNA binding protein 1 (PAI-1 mRNA-binding protein variant).
SERPINE1 mRNA binding protein 1 isoform 3.

Internal acceptor

Protein motif
chr1
HIX0000690
HIT000261866
HIT000493948
DEPDC1
DEPDC1
DEP domain containing 1 isoform b.
Similar to DEP domain containing 1 isoform b.

Cassette

Protein motif
chr1
HIX0000772
HIT000017105
HIT000050882
LRRC8D
LRRC8D
Leucine-rich repeat-containing protein 8D.
Leucine-rich repeat-containing protein 8D.

Alternative first exon

chr1
HIX0000774
HIT000334250
HIT000498331
ZNF326
ZNF326
A-kinase anchoring protein 95 (AKAP95) family protein.
A-kinase anchoring protein 95 (AKAP95) family protein.

Cassette

Internal donor

chr1
HIX0000872
HIT000009384
HIT000032023
DENND2D
DENND2D
Similar to DENN/MADD domain containing 2D.
DENN/MADD domain containing 2D.

Alternative first exon

Subcellular localization signal
chr1
HIX0001015
HIT000037190
HIT000038083
APH1A
APH1A
Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) (Presenilin- stabilization factor).
Anterior pharynx defective 1 homolog A isoform 2.

Retained intron

chr1
HIX0001017
HIT000040398
HIT000053096
C1orf51
C1orf51
Conserved hypothetical protein.
Conserved hypothetical protein.

5'-end AS

chr1
HIX0001032
HIT000029622
HIT000263101
ENSA
ENSA
Alpha-endosulfine (ARPP-19e).
Endosulfine alpha isoform 4.

3'-end AS

chr1
HIX0001032
HIT000029622
HIT000263368
ENSA
ENSA
Alpha-endosulfine (ARPP-19e).
Endosulfine alpha isoform 8.

3'-end AS

chr1
HIX0001032
HIT000263101
HIT000263368
ENSA
ENSA
Endosulfine alpha isoform 4.
Endosulfine alpha isoform 8.

3'-end AS

chr1
HIX0001108
HIT000055796
HIT000434708
SHC1
SHC1
Similar to Src homology 2 domain-containing transforming protein 1 isoform p66 (Fragment).
SHC (Src homology 2 domain containing) transforming protein 1 isoform p52Shc.

5'-end AS

Subcellular localization signal
chr1
HIX0001301
HIT000336901
HIT000501883
RCSD1
RCSD1
Capz-interacting protein (Protein kinase substrate CapZIP) (RCSD domain-containing protein 1).
Similar to Capz-interacting protein (Protein kinase substrate CapZIP) (RCSD domain-containing protein 1).

Cassette

chr1
HIX0001508
HIT000020671
HIT000249707
TMCC2
TMCC2
Similar to Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).
Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).

Alternative first exon

chr1
HIX0001530
HIT000052734
HIT000422658
RASSF5
RASSF5
Ras association (RalGDS/AF-6) domain family 5 isoform C.
Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

Alternative first exon

GO
chr1
HIX0001591
HIT000003588
HIT000052677
GPATCH2
GPATCH2
G patch domain-containing protein 2.
Similar to G patch domain-containing protein 2.

Alternative last exon

GO
chr2
HIX0001778
HIT000033209
HIT000424658
ACP1
ACP1
Acid phosphatase 1 isoform b.
Low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48) (LMW-PTPase) (LMW-PTP) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1) (Adipocyte acid phosphatase).

Cassette

Mutually exclusive

Protein motif
chr2
HIX0001806
HIT000000117
HIT000260829
ASAP2
ASAP2
Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).
Arf GTPase activating protein family protein.

Cassette

Subcellular localization signal
chr2
HIX0001988
HIT000038192
HIT000491785
SRSF7
SRSF7
Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).
Similar to Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

Cassette

chr2
HIX0002017
HIT000000153
HIT000435944
PREPL
PREPL
Similar to Prolyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like).
Similar to Prolyl endopeptidase-like isoform D.

Cassette

chr2
HIX0002195
HIT000339869
HIT000387254
DOK1
DOK1
Similar to Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).
Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

Cassette

chr2
HIX0002278
HIT000262510
HIT000499944
LMAN2L
LMAN2L
VIP36-like protein precursor (Lectin mannose-binding 2-like) (LMAN2- like protein).
Legume-like lectin family protein.

Cassette

Protein motif
Subcellular localization signal
chr2
HIX0002389
HIT000034545
HIT000423723
IL1RN
IL1RN
Interleukin 1 receptor antagonist isoform 3.
Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IL-1RN) (IRAP) (IL1 inhibitor) (ICIL-1RA) (Anakinra).

5'-end AS

GO
Subcellular localization signal
chr2
HIX0002610
HIT000011674
HIT000035237
CHN1
CHN1
Similar to N-chimaerin (NC) (N-chimerin) (Alpha-chimerin) (A-chimaerin) (Rho GTPase-activating protein 2).
N-chimaerin (NC) (N-chimerin) (Alpha-chimerin) (A-chimaerin) (Rho GTPase-activating protein 2).

5'-end AS

GO
Subcellular localization signal
chr2
HIX0002804
HIT000027683
HIT000055160
FN1
FN1
Fibronectin 1 isoform 6 preproprotein.
Fibronectin 1 isoform 5 preproprotein.

Internal acceptor

Protein motif
chr2
HIX0002804
HIT000027683
HIT000055421
FN1
FN1
Fibronectin 1 isoform 6 preproprotein.
Similar to Fibronectin ED-A (Fragment).

Cassette

Internal acceptor

Protein motif
chr2
HIX0002804
HIT000055160
HIT000055421
FN1
FN1
Fibronectin 1 isoform 5 preproprotein.
Similar to Fibronectin ED-A (Fragment).

Cassette

Protein motif
chr3
HIX0003322
HIT000424516
HIT000492732
RBM6
RBM6
RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).
Similar to RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

Cassette

chr3
HIX0003344
HIT000339768
HIT000388011
POC1A
POC1A
WD40 repeat-like domain containing protein.
WD repeat-containing protein 51A.

Cassette

chr3
HIX0003388
HIT000335849
HIT000494669
ARHGEF3
ARHGEF3
Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).
Rho GTP exchange factor family protein.

Alternative first exon

Protein motif
Subcellular localization signal
chr3
HIX0003447
HIT000024461
HIT000040237
MITF
MITF
Microphthalmia-associated transcription factor isoform 1.
Microphthalmia-associated transcription factor isoform 5.

Alternative first exon

chr3
HIX0003447
HIT000024461
HIT000261806
MITF
MITF
Microphthalmia-associated transcription factor isoform 1.
Microphthalmia-associated transcription factor isoform 4.

Internal acceptor

Alternative first exon

chr3
HIX0003622
HIT000024220
HIT000029555
UMPS
UMPS
Similar to Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRTase); Orotidine 5'- phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)].

Cassette

chr3
HIX0003815
HIT000048016
HIT000433936

Similar to Structural maintenance of chromosomes protein 4 (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog).
Similar to Structural maintenance of chromosomes protein 4 (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog).

Internal acceptor

Subcellular localization signal
chr3
HIX0003933
HIT000024574
HIT000036333
EIF4A2
EIF4A2
Similar to Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).
Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

Cassette

Protein motif
Subcellular localization signal
chr4
HIX0004015
HIT000053871
HIT000335954
CTBP1
CTBP1
C-terminal binding protein 1 isoform 2.
C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

Cassette

chr4
HIX0004166
HIT000018400
HIT000053510
UBE2K
UBE2K
Similar to Ubiquitin-conjugating enzyme E2-25K isoform 3.
Ubiquitin-conjugating enzyme E2 K (EC 6.3.2.19) (Ubiquitin-conjugating enzyme E2-25 kDa) (E2(25K)) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Huntingtin-interacting protein 2) (HIP-2).

Internal donor

Subcellular localization signal
chr4
HIX0004298
HIT000000385
HIT000035409
G3BP2
G3BP2
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2).
Ras-GTPase activating protein SH3 domain-binding protein 2 isoform b.

Cassette

Alternative first exon

chr4
HIX0004387
HIT000030668
HIT000335896
RAP1GDS1
RAP1GDS1
RAP1, GTP-GDP dissociation stimulator 1 isoform 2.
RAP1, GTP-GDP dissociation stimulator 1 isoform 5.

Cassette

Protein motif
chr4
HIX0004441
HIT000010305
HIT000030308
ELOVL6
ELOVL6
Elongation of very long chain fatty acids-like 6.
Elongation of very long chain fatty acids-like 6.

Retained intron

chr4
HIX0004452
HIT000012256
HIT000041719
CAMK2D
CAMK2D
Calcium/calmodulin-dependent protein kinase II delta isoform 2.
Calcium/calmodulin-dependent protein kinase II delta isoform 1.

3'-end AS

GO
chr4
HIX0004586
HIT000033006
HIT000422219
FGG
FGG
Fibrinogen, gamma chain isoform gamma-A precursor.
Fibrinogen gamma chain precursor.

3'-end AS

Subcellular localization signal
chr5
HIX0004822
HIT000056198
HIT000261199
EGFLAM
EGFLAM
EGF-like, fibronectin type III and laminin G domains isoform 4.
EGF-like, fibronectin type III and laminin G domains isoform 3.

Cassette

Protein motif
chr5
HIX0004914
HIT000041152
HIT000335096
PIK3R1
PIK3R1
Similar to Phosphoinositide-3-kinase regulatory subunit (Fragment).
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85 subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

Alternative first exon

Protein motif
GO
Subcellular localization signal
chr5
HIX0004921
HIT000031545_03
HIT000033166_03
TAF9
TAF9
Similar to TAF9 RNA polymerase II, TATA box binding protein-associated factor isoform b.
TAF9 RNA polymerase II, TATA box binding protein-associated factor isoform b.

Alternative last exon

chr5
HIX0005002
HIT000002068
HIT000494482
SSBP2
SSBP2
Similar to Single-stranded DNA-binding protein 2-like protein (Fragment).
Similar to Single-stranded DNA-binding protein 2-like protein (Fragment).

Cassette

Internal acceptor

Protein motif
GO
chr5
HIX0005012
HIT000041161
HIT000057230
EDIL3
EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).
Similar to EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

Cassette

Protein motif
chr5
HIX0005206
HIT000422748
HIT000492380
BRD8
BRD8
Bromodomain containing 8 isoform 1.
Similar to Bromodomain containing 8 isoform 1.

Cassette

Internal donor

GO
chr5
HIX0005252
HIT000000305
HIT000038619
PCDHGA12
PCDHGC3
Protocadherin gamma-A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3).
Protocadherin gamma-C3 precursor (PCDH-gamma-C3) (Protocadherin-43) (PC-43) (Protocadherin-2).

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr5
HIX0005252
HIT000000305
HIT000053681
PCDHGA12
PCDHGB7
Protocadherin gamma-A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3).
Protocadherin gamma-B7 precursor (PCDH-gamma-B7).

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr5
HIX0005252
HIT000000305
HIT000435515
PCDHGA12
PCDHGA6
Protocadherin gamma-A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3).
Protocadherin gamma-A6 precursor (PCDH-gamma-A6).

Alternative first exon

Protein motif
Transmembrane domain
chr5
HIX0005252
HIT000038619
HIT000053681
PCDHGC3
PCDHGB7
Protocadherin gamma-C3 precursor (PCDH-gamma-C3) (Protocadherin-43) (PC-43) (Protocadherin-2).
Protocadherin gamma-B7 precursor (PCDH-gamma-B7).

Alternative first exon

Protein motif
Transmembrane domain
chr5
HIX0005252
HIT000038619
HIT000435515
PCDHGC3
PCDHGA6
Protocadherin gamma-C3 precursor (PCDH-gamma-C3) (Protocadherin-43) (PC-43) (Protocadherin-2).
Protocadherin gamma-A6 precursor (PCDH-gamma-A6).

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr5
HIX0005252
HIT000053681
HIT000435515
PCDHGB7
PCDHGA6
Protocadherin gamma-B7 precursor (PCDH-gamma-B7).
Protocadherin gamma-A6 precursor (PCDH-gamma-A6).

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr5
HIX0005320
HIT000002774
HIT000426623
DCTN4
DCTN4
Dynactin subunit 4 (Dynactin subunit p62).
Dynactin p62 family protein.

Cassette

Protein motif
Subcellular localization signal
chr5
HIX0005406
HIT000053427
HIT000496399

Kv channel interacting protein 1 isoform 2.
Kv channel interacting protein 1 isoform 3.

Alternative first exon

chr5
HIX0005413
HIT000000421
HIT000040144
FBXW11
FBXW11
F-box/WD repeat-containing protein 11 (F-box/WD repeat-containing protein 1B) (F-box and WD repeats protein beta-TrCP2) (Homologous to Slimb protein) (HOS).
F-box and WD repeat domain containing 11 isoform B.

Cassette

Mutually exclusive

Subcellular localization signal
chr5
HIX0005476
HIT000022511
HIT000034306
HNRNPAB
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B isoform a.
Heterogeneous nuclear ribonucleoprotein A/B isoform b.

Cassette

Protein motif
chr6
HIX0005572
HIT000027631
HIT000432769
GCNT2
GCNT2
I beta-1,6-N-acetylglucosaminyltransferase C form (Glucosaminyl (N- acetyl) transferase 2, I-branching enzyme) (I blood group) (Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group), isoform CRA_a) (Beta-1,6-N-acetylglucosaminyltransferase 3) (Putative uncharacterized protein DKFZp313I032).
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (EC 2.4.1.150) (N-acetylglucosaminyltransferase) (I-branching enzyme) (IGNT).

Alternative first exon

Protein motif
Transmembrane domain
chr6
HIX0005791
HIT000001094
HIT000052348
PACSIN1
PACSIN1
Protein kinase C and casein kinase substrate in neurons protein 1.
Protein kinase C and casein kinase substrate in neurons protein 1.

Alternative first exon

chr6
HIX0005833
HIT000006057
HIT000436100
MTCH1
MTCH1
Similar to Mitochondrial carrier homolog 1.
Mitochondrial carrier homolog 1 (Presenilin-associated protein).

Internal donor

Protein motif
Subcellular localization signal
chr6
HIX0005875
HIT000259043
HIT000425936
MED20
MED20
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP).
Similar to Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP).

Cassette

Protein motif
GO
chr6
HIX0005935
HIT000015857
HIT000052045
RCAN2
RCAN2
Similar to Calcipressin-2 (Regulator of calcineurin 2) (Down syndrome candidate region 1-like 1) (Thyroid hormone-responsive protein ZAKI-4) (Myocyte- enriched calcineurin-interacting protein 2) (MCIP2).
Calcipressin-2 (Regulator of calcineurin 2) (Down syndrome candidate region 1-like 1) (Thyroid hormone-responsive protein ZAKI-4) (Myocyte- enriched calcineurin-interacting protein 2) (MCIP2).

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr6
HIX0005983
HIT000056728
HIT000497201
ZNF451
ZNF451
Zinc finger, C2H2-type domain containing protein.
Conserved hypothetical protein.

Alternative last exon

Protein motif
GO
chr6
HIX0006122
HIT000340165
HIT000423348
SESN1
SESN1
Sestrin 1.
Sestrin-1 (p53-regulated protein PA26).

Alternative first exon

Protein motif
Subcellular localization signal
chr6
HIX0006234
HIT000011691
HIT000023339
SGK1
SGK1
Serum/glucocorticoid regulated kinase 1.
Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

Alternative first exon

GO
Subcellular localization signal
chr6
HIX0006234
HIT000011691
HIT000493312
SGK1
SGK1
Serum/glucocorticoid regulated kinase 1.
Serine/threonine protein kinase-related domain containing protein.

Alternative first exon

GO
Subcellular localization signal
chr6
HIX0006234
HIT000023339
HIT000493312
SGK1
SGK1
Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).
Serine/threonine protein kinase-related domain containing protein.

Alternative first exon

Subcellular localization signal
chr7
HIX0006465
HIT000424603
HIT000424612
RAC1
RAC1
Ras-related C3 botulinum toxin substrate 1 precursor (p21-Rac1) (Ras- like protein TC25) (Cell migration-inducing gene 5 protein).
Ras-related C3 botulinum toxin substrate 1 isoform Rac1b.

Cassette

Protein motif
Subcellular localization signal
chr7
HIX0006558
HIT000009689
HIT000340284
CHN2
CHN2
Beta chimerin isoform 1.
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3).

5'-end AS

GO
chr7
HIX0006587
HIT000037362
HIT000264478
NT5C3
NT5C3
5'-nucleotidase, cytosolic III isoform 2.
Cytosolic 5'-nucleotidase 3 (EC 3.1.3.5) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36).

Cassette

Alternative first exon

Protein motif
Subcellular localization signal
chr7
HIX0006602
HIT000489310
HIT000502468
KIAA0895
KIAA0895
Conserved hypothetical protein.
Conserved hypothetical protein.

3'-end AS

chr7
HIX0006640
HIT000010639
HIT000496661
DBNL
DBNL
Drebrin-like isoform c.
Similar to Drebrin-like isoform a.

Internal acceptor

Internal donor

Subcellular localization signal
chr7
HIX0006640
HIT000035366
HIT000496661
DBNL
DBNL
Drebrin-like isoform a.
Similar to Drebrin-like isoform a.

Internal donor

Subcellular localization signal
chr7
HIX0006982
HIT000037707
HIT000425027

SYPL1
Synaptophysin-like 1 isoform b.
Synaptophysin-like protein 1 (Pantophysin).

5'-end AS

chr7
HIX0007018
HIT000423668
HIT000426367
CAV1
CAV1
Caveolin-1.
Similar to Caveolin-1.

5'-end AS

chr7
HIX0007050
HIT000011281
HIT000488037
IMPDH1
IMPDH1
Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).
IMP dehydrogenase/GMP reductase family protein.

Internal donor

Protein motif
chr7
HIX0007050
HIT000011281
HIT000492567
IMPDH1
IMPDH1
Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).
Similar to Inosine monophosphate dehydrogenase 1 isoform b.

5'-end AS

chr7
HIX0007055
HIT000010732
HIT000036242
CALU
CALU
Conserved hypothetical protein.
EF hand domain containing protein.

Cassette

Mutually exclusive

Protein motif
GO
chr7
HIX0007065
HIT000000545
HIT000499686
AHCYL2
AHCYL2
S-adenosyl-L-homocysteine hydrolase family protein.
Similar to Adenosylhomocysteinase (EC 3.3.1.1) (Fragment).

Alternative first exon

Subcellular localization signal
chr7
HIX0007112
HIT000051429
HIT000494989
CNOT4
CNOT4
CCR4-NOT transcription complex, subunit 4 isoform b.
Similar to CCR4-NOT transcription complex, subunit 4 isoform b.

Alternative last exon

chr7
HIX0007142
HIT000001922
HIT000261595
MKRN1
MKRN1
Conserved hypothetical protein.
Makorin-1 (RING finger protein 61).

3'-end AS

GO
chr7
HIX0007256
HIT000036478
HIT000042146
UBE3C
UBE3C
Similar to Ubiquitin-protein ligase E3C (EC 6.3.2.-).
Ubiquitin-protein ligase E3C (EC 6.3.2.-).

3'-end AS

GO
Subcellular localization signal
chr8
HIX0007547
HIT000423598
HIT000425477
PDE7A
PDE7A
Phosphodiesterase 7A isoform a.
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (HCP1) (TM22).

Alternative first exon

Subcellular localization signal
Transmembrane domain
chr8
HIX0007623
HIT000019398
HIT000043310
RALYL
RALYL
Similar to RALY RNA binding protein-like isoform 1.
Similar to RALY RNA binding protein-like isoform 2.

Alternative first exon

GO
chr8
HIX0007717
HIT000041422
HIT000493998
LRP12
LRP12
Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).
CUB domain containing protein.

Cassette

Protein motif
Subcellular localization signal
Transmembrane domain
chr8
HIX0007797
HIT000033004
HIT000431450
SLA
SLA
SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).
Src-like-adaptor.

5'-end AS

Subcellular localization signal
chr9
HIX0008165
HIT000001861
HIT000049116
OGN
OGN
Mimecan precursor (Osteoglycin) (Osteoinductive factor) (OIF).
Mimecan precursor (Osteoglycin) (Osteoinductive factor) (OIF).

5'-end AS

chr9
HIX0008395
HIT000488356
HIT000490870
GARNL3
GARNL3
GTPase-activating Rap/Ran-GAP domain-like protein 3.
Similar to GTPase-activating Rap/Ran-GAP domain-like protein 3.

5'-end AS

Subcellular localization signal
chr9
HIX0008418
HIT000001611
HIT000337483
SLC25A25
SLC25A25
Similar to Solute carrier family 25, member 25 isoform c.
Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium- binding mitochondrial carrier protein 2) (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Solute carrier family 25 member 25).

Cassette

Alternative first exon

Protein motif
GO
Subcellular localization signal
chr9
HIX0008418
HIT000001611
HIT000423788
SLC25A25
SLC25A25
Similar to Solute carrier family 25, member 25 isoform c.
Solute carrier family 25, member 25 isoform b.

Cassette

Alternative first exon

GO
Subcellular localization signal
chr9
HIX0008418
HIT000337483
HIT000423788
SLC25A25
SLC25A25
Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium- binding mitochondrial carrier protein 2) (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Solute carrier family 25 member 25).
Solute carrier family 25, member 25 isoform b.

Alternative first exon

Protein motif
GO
Subcellular localization signal
chr9
HIX0008434
HIT000041705
HIT000495418
SET
SET
SET translocation (myeloid leukemia-associated) isoform 2.
Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

Alternative first exon

Protein motif
Subcellular localization signal
chr10
HIX0008722
HIT000039789
HIT000424620
ABI1
ABI1
Abl-interactor 1 isoform d.
Abl-interactor 1 isoform c.

Cassette

Protein motif
Subcellular localization signal
chr10
HIX0008733
HIT000012466
HIT000031825
WAC
WAC
Similar to BM-016.
Similar to BM-016.

Alternative first exon

chr10
HIX0008751
HIT000051731
HIT000494300

Similar to Enhancer of polycomb homolog 1.
Similar to Enhancer of polycomb homolog 1.

Alternative first exon

Protein motif
Subcellular localization signal
chr10
HIX0008924
HIT000031050
HIT000431313
ANXA7
ANXA7
Annexin VII isoform 1.
Annexin A7 (Annexin-7) (Annexin VII) (Synexin).

Cassette

Protein motif
Subcellular localization signal
chr10
HIX0009044
HIT000040552
HIT000488481
EXOC6
EXOC6
Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15- like protein 1).
Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15- like protein 1).

Internal donor

Protein motif
Subcellular localization signal
chr10
HIX0009167
HIT000340584
HIT000495495
C10orf26
C10orf26
Conserved hypothetical protein.
Conserved hypothetical protein.

Alternative first exon

Subcellular localization signal
chr10
HIX0009254
HIT000423492
HIT000423781
TIAL1
TIAL1
Nucleolysin TIAR (TIA-1-related protein).
TIA-1 related protein isoform 2.

Internal acceptor

Protein motif
chr11
HIX0009371
HIT000031261
HIT000056553
CARS
CARS
Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).
Cysteinyl-tRNA synthetase isoform c.

Cassette

Subcellular localization signal
chr11
HIX0009371
HIT000031261
HIT000493138
CARS
CARS
Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).
Similar to Cysteinyl-tRNA synthetase isoform c.

Cassette

Internal donor

Subcellular localization signal
chr11
HIX0009504
HIT000030893
HIT000037095
HTATIP2
HTATIP2
Oxidoreductase HTATIP2 (EC 1.1.1.-) (HIV-1 TAT-interactive protein 2) (30 kDa HIV-1 TAT-interacting protein).
Oxidoreductase HTATIP2 (EC 1.1.1.-) (HIV-1 TAT-interactive protein 2) (30 kDa HIV-1 TAT-interacting protein).

5'-end AS

chr11
HIX0009583
HIT000038093
HIT000493912
API5
API5
Apoptosis inhibitor 5.
Apoptosis inhibitory 5 family protein.

Internal acceptor

Protein motif
chr11
HIX0009770
HIT000033637
HIT000490861
SF1
SF1
Splicing factor 1 isoform 3.
Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

Internal acceptor

Alternative last exon

chr11
HIX0009921
HIT000013771
HIT000335718
RAB6A
RAB6A
RAB6A, member RAS oncogene family isoform a.
Ras-related protein Rab-6A (Rab-6).

Cassette

Mutually exclusive

Protein motif
GO
chr12
HIX0010381
HIT000030962
HIT000423218
PTPN6
PTPN6
Protein tyrosine phosphatase, non-receptor type 6 isoform 2.
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

Alternative first exon

Protein motif
chr12
HIX0010386
HIT000032062
HIT000032241

USP5
Ubiquitin specific peptidase 5 isoform 2.
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

Internal donor

Protein motif
Subcellular localization signal
chr12
HIX0010973
HIT000037051
HIT000432418
UNG
UNG
Uracil-DNA glycosylase isoform UNG1 precursor.
Uracil-DNA glycosylase (EC 3.2.2.-) (UDG).

5'-end AS

Subcellular localization signal
chr12
HIX0010992
HIT000025210
HIT000029973
VPS29
VPS29
Uncharacterised protein family UPF0025 protein.
Vacuolar protein sorting 29 isoform 2.

Internal donor

Protein motif
chr13
HIX0011196
HIT000001794
HIT000037074
POLR1D
POLR1D
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (DNA-directed RNA polymerase I subunit D) (DNA- directed RNA polymerase I 16 kDa polypeptide) (RPA16) (RPC16) (hRPA19) (AC19).
Polymerase (RNA) I polypeptide D isoform 2.

Alternative last exon

Protein motif
GO
Subcellular localization signal
chr13
HIX0011281
HIT000423548
HIT000500492
TSC22D1
TSC22D1
TSC22 domain family, member 1 isoform 2.
TSC-22 / Dip / Bun family protein.

Alternative first exon

Protein motif
Subcellular localization signal
chr14
HIX0011694
HIT000025281
HIT000036164
MUDENG
MUDENG
Clathrin adaptor, mu subunit, C-terminal domain containing protein.
Clathrin adaptor, mu subunit, C-terminal domain containing protein.

3'-end AS

Protein motif
chr14
HIX0011874
HIT000044548
HIT000335226
TTC8
TTC8
Tetratricopeptide repeat domain 8 isoform A.
Tetratricopeptide repeat domain 8 isoform B.

Cassette

chr15
HIX0012052
HIT000035026
HIT000434177
GABRB3
Gamma-aminobutyric acid receptor subunit beta-3 precursor (GABA(A) receptor subunit beta-3).
Gamma-aminobutyric acid (GABA) A receptor, beta 3 isoform 2 precursor.

Alternative first exon

Protein motif
GO
Transmembrane domain
chr15
HIX0012129
HIT000387848
HIT000492780
C15orf23
C15orf23
Conserved hypothetical protein.
Conserved hypothetical protein.

Cassette

Subcellular localization signal
chr15
HIX0012224
HIT000002271
HIT000035914
COPS2
COPS2
Proteasome component region PCI domain containing protein.
COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TRIP-15) (Alien homolog).

Internal acceptor

chr15
HIX0012225
HIT000027657
HIT000032243
GALK2
GALK2
Similar to Galactokinase 2 isoform 2.
N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2).

Alternative first exon

Protein motif
GO
chr15
HIX0012225
HIT000027657
HIT000495985
GALK2
GALK2
Similar to Galactokinase 2 isoform 2.
Similar to Galactokinase 2 isoform 2.

Alternative first exon

chr15
HIX0012317
HIT000033219
HIT000494011
TPM1
TPM1
Tropomyosin 1 alpha chain isoform 5.
Tropomyosin alpha-1 chain (Tropomyosin-1) (Alpha-tropomyosin).

Cassette

Internal donor

Mutually exclusive

Protein motif
chr15
HIX0012471
HIT000026449
HIT000039318
IDH3A
IDH3A
Similar to Isocitrate dehydrogenase 3 (NAD+) alpha (Fragment).
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

5'-end AS

Subcellular localization signal
chr15
HIX0012471
HIT000026449
HIT000490626
IDH3A
IDH3A
Similar to Isocitrate dehydrogenase 3 (NAD+) alpha (Fragment).
Similar to Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

5'-end AS

chr15
HIX0012531
HIT000011066
HIT000012192
WDR73
WDR73
WD repeat-containing protein 73.
Similar to WD repeat-containing protein 73.

Retained intron

chr15
HIX0012591
HIT000082001
HIT000082015
RGMA
RGMA
Similar to RGM domain family, member A.
RGM domain family, member A.

5'-end AS

chr16
HIX0012642
HIT000003567
HIT000031506
LUC7L
LUC7L
LUC7-like isoform a.
LUC7-like isoform a.

3'-end AS

chr16
HIX0012719
HIT000030553
HIT000497724
RNPS1
RNPS1
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).
Similar to RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

Cassette

Internal acceptor

Internal donor

chr16
HIX0012719
HIT000030553
HIT000499745
RNPS1
RNPS1
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).
Similar to RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

Cassette

chr16
HIX0012725
HIT000053771
HIT000266188
MLST8
MLST8
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (mLST8) (G protein beta subunit-like) (Protein GbetaL) (Gable).
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (mLST8) (G protein beta subunit-like) (Protein GbetaL) (Gable).

Retained intron

chr16
HIX0012782
HIT000035494
HIT000041419_03
DNAJA3
DNAJA3
DnaJ homolog subfamily A member 3, mitochondrial precursor (Tumorous imaginal discs protein Tid56 homolog) (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57).
Heat shock protein DnaJ family protein.

Cassette

chr16
HIX0012827
HIT000004487
HIT000018720
CPPED1
CPPED1
Uncharacterized metallophosphoesterase CSTP1 (EC 3.1.-.-) (Complete S- transactivated protein 1).
Similar to Uncharacterized metallophosphoesterase CSTP1 (EC 3.1.-.-) (Complete S- transactivated protein 1).

Internal acceptor

Internal donor

Subcellular localization signal
chr16
HIX0013075
HIT000031582
HIT000434292
DOK4
DOK4
Docking protein 4 (Downstream of tyrosine kinase 4).
Docking protein 4 (Downstream of tyrosine kinase 4).

5'-end AS

chr16
HIX0013164
HIT000039130
HIT000488530
SLC12A4
SLC12A4
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).
Na/K/Cl co-transporter superfamily protein.

Internal donor

Protein motif
chr16
HIX0013214
HIT000013456
HIT000035522
MARVELD3
MARVELD3
MARVEL domain containing 3 isoform 1.
MARVEL domain containing 3 isoform 2.

Alternative last exon

Protein motif
GO
Transmembrane domain
chr16
HIX0013243
HIT000010880
HIT000433588
BCAR1
BCAR1
Similar to Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

Alternative first exon

Protein motif
chr16
HIX0013334
HIT000053467
HIT000494878
ZC3H18
ZC3H18
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1).
Similar to Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1).

Cassette

GO
chr17
HIX0013663
HIT000020424
HIT000056413
C17orf63
C17orf63
Conserved hypothetical protein.
Conserved hypothetical protein.

Internal acceptor

Alternative first exon

chr17
HIX0013704
HIT000029623
HIT000423399
PSMD11
PSMD11
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5).

Retained intron

chr17
HIX0013825
HIT000032659
HIT000490299
ACLY
ACLY
ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme).
ATP citrate lyase isoform 2.

Cassette

Internal acceptor

Protein motif
chr17
HIX0014004
HIT000015069
HIT000051622
HLF
HLF
Similar to Hepatic leukemia factor.
Hepatic leukemia factor.

5'-end AS

Subcellular localization signal
chr17
HIX0014004
HIT000015069
HIT000490350
HLF
HLF
Similar to Hepatic leukemia factor.
Similar to Hepatic leukemia factor.

Internal acceptor

Subcellular localization signal
chr17
HIX0014261
HIT000034779
HIT000434643
PCYT2
PCYT2
Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (Phosphorylethanolamine transferase) (CTP:phosphoethanolamine cytidylyltransferase).
Similar to Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (Phosphorylethanolamine transferase) (CTP:phosphoethanolamine cytidylyltransferase).

Cassette

chr18
HIX0014326
HIT000010338
HIT000425335
PPP4R1
PPP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
Protein phosphatase 4, regulatory subunit 1 isoform b.

Internal acceptor

Subcellular localization signal
chr18
HIX0014345
HIT000423446
HIT000425367
PTPN2
PTPN2
Protein tyrosine phosphatase, non-receptor type 2 isoform 2.
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

3'-end AS

Protein motif
Subcellular localization signal
Transmembrane domain
chr12
HIX0014387
HIT000099505
HIT000264271
HNRNPA1
HNRNPA1
Heterogeneous nuclear ribonucleoprotein A1 isoform a.
Heterogeneous nuclear ribonucleoprotein A1 isoform a.

Alternative last exon

chr19
HIX0014689
HIT000264400
HIT000423993
RFX2
RFX2
Regulatory factor X2 isoform a.
Regulatory factor X2 isoform b.

Cassette

Protein motif
chr19
HIX0015150
HIT000030996
HIT000034717
HNRNPUL1
HNRNPUL1
Heterogeneous nuclear ribonucleoprotein U-like 1 isoform d.
Heterogeneous nuclear ribonucleoprotein U-like 1 isoform d.

Internal donor

GO
Subcellular localization signal
chr19
HIX0015316
HIT000021638
HIT000050396
SNRNP70
SNRNP70
Similar to HU1-70K snRNP protein (RNPH2, part 1) (Fragment).
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

Cassette

chr20
HIX0015669
HIT000032171
HIT000335197
SEC23B
SEC23B
Protein transport protein Sec23B (SEC23-related protein B).
Protein transport protein Sec23B (SEC23-related protein B).

Internal donor

chr20
HIX0016013
HIT000011682
HIT000032943
TPD52L2
TPD52L2
Tumor protein D52-like 2 isoform d.
Tumor protein D54 (hD54) (Tumor protein D52-like 2).

Cassette

Protein motif
chr20
HIX0016013
HIT000011682
HIT000491688
TPD52L2
TPD52L2
Tumor protein D52-like 2 isoform d.
Tumor protein D52-like 2 isoform f.

Cassette

chr20
HIX0016013
HIT000032943
HIT000491688
TPD52L2
TPD52L2
Tumor protein D54 (hD54) (Tumor protein D52-like 2).
Tumor protein D52-like 2 isoform f.

Cassette

Protein motif
chr21
HIX0016091
HIT000017051
HIT000494068
RCAN1
RCAN1
Calcipressin-1 (Regulator of calcineurin 1) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Adapt78).
Calcipressin 1 isoform c.

Alternative first exon

Protein motif
Subcellular localization signal
chr21
HIX0016147
HIT000039148
HIT000422383
NDUFV3
NDUFV3
Similar to NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial precursor (NADH-ubiquinone oxidoreductase 9 kDa subunit) (Complex I- 9kD) (CI-9kD) (Renal carcinoma antigen NY-REN-4).
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial precursor (NADH-ubiquinone oxidoreductase 9 kDa subunit) (Complex I- 9kD) (CI-9kD) (Renal carcinoma antigen NY-REN-4).

Cassette

Subcellular localization signal
chr22
HIX0016238
HIT000032689
HIT000487747
CDC45
CDC45
CDC45-related protein (PORC-PI-1) (Cdc45).
Similar to CDC45-related protein (PORC-PI-1) (Cdc45).

Cassette

Protein motif
chr22
HIX0016383
HIT000017551
HIT000042078
SMTN
SMTN
Similar to Smoothelin-b (Fragment).
Smoothelin isoform b.

Cassette

Alternative first exon

chr22
HIX0016405
HIT000033741
HIT000492465
FBXO7
FBXO7
F-box only protein 7.
F-box only protein 7 isoform 2.

Internal acceptor

Alternative first exon

Subcellular localization signal
chr22
HIX0016419
HIT000011827
HIT000039880
RBM9
RBM9
Similar to RBM9 (Fragment).
RNA binding motif protein 9 isoform 1.

Alternative first exon

Protein motif
chr22
HIX0016490
HIT000029876
HIT000422304
SYNGR1
SYNGR1
Synaptogyrin 1 isoform 1b.
Synaptogyrin-1.

Alternative last exon

Protein motif
Transmembrane domain
chr22
HIX0016498
HIT000039962
HIT000040062
GRAP2
GRAP2
GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).
GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

5'-end AS

chr22
HIX0016544
HIT000099090
HIT000259637
POLDIP3
POLDIP3
Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46).
DNA polymerase delta interacting protein 3 isoform 2.

Cassette

chrX
HIX0016674
HIT000264680
HIT000494545
AP1S2
AP1S2
AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma1B-adaptin) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).
Similar to AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma1B-adaptin) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

Alternative last exon

Protein motif
Subcellular localization signal
chrX
HIX0016726
HIT000038894
HIT000045415
SRPX
SRPX
Sushi repeat-containing protein SRPX precursor.
Similar to Sushi repeat containing protein SRPX-like protein (Fragment).

Cassette

chrX
HIX0017014
HIT000051655
HIT000423774
6-Sep
6-Sep
Septin-6.
Septin 6 isoform D.

Alternative last exon

Protein motif
chrX
HIX0017024
HIT000031322
HIT000423887

LAMP2
Lysosomal-associated membrane protein 2 isoform B precursor.
Lysosome-associated membrane glycoprotein 2 precursor (LAMP-2) (CD107b antigen).

Alternative last exon

Protein motif
Transmembrane domain
chrX
HIX0017026
HIT000430859
HIT000489458
MCTS1
MCTS1
Malignant T cell amplified sequence 1 (Oncogene MCT-1).
Translation machinery-associated RNA binding protein, predicted family protein.

Alternative first exon

Protein motif
chrX
HIX0017147
HIT000054844
HIT000422241
MECP2
MECP2
Similar to Methyl CpG binding protein 2 (Fragment).
Similar to Methyl CpG binding protein 2 (Fragment).

Cassette

Protein motif
chr1
HIX0017291
HIT000051321
HIT000054490
PRKACB
PRKACB
Similar to CAMP-dependent protein kinase catalytic subunit beta isoform 3.
CAMP-dependent protein kinase catalytic subunit beta isoform 1.

Alternative first exon

Protein motif
GO
Subcellular localization signal
chr1
HIX0017291
HIT000051321
HIT000498999
PRKACB
PRKACB
Similar to CAMP-dependent protein kinase catalytic subunit beta isoform 3.
Similar to cAMP-dependent protein kinase catalytic subunit beta (EC 2.7.11.11) (PKA C-beta).

Alternative first exon

GO
Subcellular localization signal
chr1
HIX0017291
HIT000054490
HIT000498999
PRKACB
PRKACB
CAMP-dependent protein kinase catalytic subunit beta isoform 1.
Similar to cAMP-dependent protein kinase catalytic subunit beta (EC 2.7.11.11) (PKA C-beta).

Alternative first exon

chr1
HIX0019159
HIT000423115
HIT000497524
MTF2
MTF2
Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal regulatory transcription factor 2) (Polycomb-like protein 2) (hPCl2).
Similar to Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal regulatory transcription factor 2) (Polycomb-like protein 2) (hPCl2).

Cassette

GO
Subcellular localization signal
chr8
HIX0019175
HIT000007916
HIT000057643
C8orf33
C8orf33
Conserved hypothetical protein.
Conserved hypothetical protein.

Retained intron

chr11
HIX0019316
HIT000029519
HIT000053247
DPAGT1
DPAGT1
UDP-N-acetylglucosamine--dolichyl-phosphate N- acetylglucosaminephosphotransferase (EC 2.7.8.15) (GPT) (G1PT) (N- acetylglucosamine-1-phosphate transferase) (GlcNAc-1-P transferase).
Similar to UDP-N-acetylglucosamine--dolichyl-phosphate N- acetylglucosaminephosphotransferase (EC 2.7.8.15) (GPT) (G1PT) (N- acetylglucosamine-1-phosphate transferase) (GlcNAc-1-P transferase).

Cassette

chr1
HIX0019798
HIT000029388
HIT000423380
C1orf43
C1orf43
NICE-3 family protein.
NICE-3 family protein.

3'-end AS

Protein motif
chr11
HIX0020040
HIT000032895
HIT000036406
EEF1G
EEF1G
Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).
Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

chr11
HIX0020446
HIT000008676
HIT000388587
TMEM134
TMEM134
Transmembrane protein 134 isoform a.
Transmembrane protein 134 isoform b.

Cassette

Protein motif
GO
Transmembrane domain
chr11
HIX0020994
HIT000029563
HIT000499360
APLP2
APLP2
Amyloidogenic glycoprotein, extracellular domain containing protein.
Amyloidogenic glycoprotein, extracellular domain containing protein.

Cassette

Protein motif
GO
Subcellular localization signal
chr8
HIX0021176
HIT000034042
HIT000425170
PUF60
PUF60
Poly-U binding splicing factor 60KDa isoform b.
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Siah-binding protein 1) (Siah-BP1) (Ro-binding protein 1) (RoBP1).

Cassette

Protein motif
Subcellular localization signal
chr19
HIX0021254
HIT000435419
HIT000491097
EPS15L1
EPS15L1
Similar to Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).
Similar to Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

3'-end AS

chr11
HIX0021346
HIT000082447
HIT000498724
RTN3
RTN3
Reticulon 3 isoform a.
Similar to Reticulon 3 isoform d.

Cassette

Protein motif
GO
Subcellular localization signal
chrX
HIX0021848
HIT000037337
HIT000487858
SH3KBP1
SH3KBP1
SH3 domain-containing kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).
SH3-domain kinase binding protein 1 isoform b.

Alternative first exon

chr11
HIX0021928
HIT000423317
HIT000488601
TRAPPC4
TRAPPC4
Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog) (Hematopoietic stem/progenitor cell protein 172).
Sybindin-like protein family protein.

Cassette

Internal donor

Protein motif
Subcellular localization signal
chr16
HIX0022308
HIT000000056_03
HIT000340496
CLEC16A
CLEC16A
C-type lectin domain family 16, member A.
Similar to Protein CLEC16A.

Internal donor

chr18
HIX0022551
HIT000040961
HIT000424183
MALT1
MALT1
Mucosa associated lymphoid tissue lymphoma translocation protein 1 isoform b.
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

Cassette

Protein motif
chr1
HIX0023526
HIT000422616
HIT000431737
KCNAB2
KCNAB2
Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2) (HKvbeta2).
Potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 2.

Cassette

Alternative first exon

Protein motif
GO
Subcellular localization signal
chr1
HIX0023614
HIT000051610
HIT000493526
ELAVL4
ELAVL4
Splicing factor ELAV/HuD family protein.
Splicing factor ELAV/HuD family protein.

Alternative first exon

chr2
HIX0023990
HIT000057565
HIT000426634
ARID5A
ARID5A
Similar to AT-rich interactive domain-containing protein 5A (ARID domain- containing protein 5A) (Modulator recognition factor 1) (MRF-1).
Similar to AT-rich interactive domain-containing protein 5A (ARID domain- containing protein 5A) (Modulator recognition factor 1) (MRF-1).

Cassette

GO
chr3
HIX0024332
HIT000432968
HIT000495007
TGFBR2
TGFBR2
TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TbetaR-II).
Transforming growth factor, beta receptor II isoform A precursor.

Cassette

Protein motif
chr4
HIX0024563
HIT000057637
HIT000423795
KCNIP4
KCNIP4
Kv channel interacting protein 4 isoform 5.
Kv channel interacting protein 4 isoform 4.

Alternative first exon

Subcellular localization signal
Transmembrane domain
chr6
HIX0025012
HIT000046056
HIT000093340
SLC16A10
SLC16A10
Monocarboxylate transporter 10 (MCT 10) (T-type amino acid transporter 1) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10).
Similar to Monocarboxylate transporter 10 (MCT 10) (T-type amino acid transporter 1) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10).

3'-end AS

Transmembrane domain
chr10
HIX0025926
HIT000051291
HIT000431459
P4HA1
P4HA1
Prolyl 4-hydroxylase subunit alpha-1 precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1).
Prolyl 4-hydroxylase, alpha I subunit isoform 1 precursor.

Cassette

Mutually exclusive

Protein motif
chr12
HIX0026349
HIT000055140
HIT000491236
NR1H4
NR1H4
Similar to Nuclear receptor subfamily 1, group H, member 4.
Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

Internal donor

Protein motif
GO
chr17
HIX0027148
HIT000094222
HIT000249832
MAP2K4
MAP2K4
Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).
Similar to Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

Cassette

Subcellular localization signal
chr19
HIX0027472
HIT000042880
HIT000052313
PKN1
PKN1
Protein kinase N1 isoform 1.
Protein kinase N1 isoform 2.

Alternative first exon

GO
chr22
HIX0027836
HIT000045129
HIT000052199
FAM19A5
FAM19A5
Family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 isoform 2.
Protein FAM19A5 precursor (Chemokine-like protein TAFA-5).

Alternative first exon

Transmembrane domain
chr22
HIX0028320
HIT000051254
HIT000422323
WNT7B
WNT7B
Protein Wnt-7b precursor.
Similar to Protein Wnt-7b precursor.

Alternative first exon

Protein motif
Subcellular localization signal
Transmembrane domain
chr11
HIX0035844
HIT000264224
HIT000488094
CRTAM
CRTAM
Cytotoxic and regulatory T-cell molecule precursor (Class-I MHC- restricted T-cell-associated molecule).
Similar to Cytotoxic and regulatory T-cell molecule precursor (Class-I MHC- restricted T-cell-associated molecule).

5'-end AS

Subcellular localization signal
Transmembrane domain
chr18
HIX0039710
HIT000335510
HIT000496128
SS18
SS18
SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).
Synovial sarcoma translocation, chromosome 18 isoform 2.

Cassette

Protein motif
Subcellular localization signal
chr6
HIX0078235
HIT000422643
HIT000431657
FGFR1OP
FGFR1OP
FGFR1 oncogene partner isoform b.
FGFR1 oncogene partner.

Cassette

chr17
HIX0079852
HIT000041735
HIT000054867
KRT222
KRT222
Keratin 222 pseudogene (Truncated type I keratin KA21, isoform CRA_a).
Similar to Keratin 222 pseudogene (Truncated type I keratin KA21, isoform CRA_a).

Internal donor

chr10
HIX0127068
HIT000041371
HIT000434446
ERLIN1
ERLIN1
Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1) (Protein KE04).
ER lipid raft associated 1.

5'-end AS

chr6
HIX0184148
HIT000028731_04
HIT000493367_01
C6orf134
C6orf134
Similar to RecName: Full=UPF0635 protein C6orf134;
Similar to RecName: Full=UPF0635 protein C6orf134;

Cassette

Protein motif
Subcellular localization signal
chr1
HIX0199819
HIT000014537
HIT000426966
GPATCH3
GPATCH3
G patch domain-containing protein 3.
Similar to G patch domain-containing protein 3.

Internal donor

Subcellular localization signal
chr1
HIX0199912
HIT000027250
HIT000027549
TXLNA
TXLNA
Alpha-taxilin.
Similar to Alpha-taxilin.

5'-end AS

chr1
HIX0199917
HIT000023148
HIT000040014
FAM76A
FAM76A
Similar to Protein FAM76A.
Similar to Protein FAM76A.

Cassette

Subcellular localization signal
chr1
HIX0199938
HIT000422974
HIT000424502
ARNT
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
Aryl hydrocarbon receptor nuclear translocator isoform 3.

Cassette

Protein motif
GO
chr2
HIX0200248
HIT000001051
HIT000051757
WDR35
WDR35
WD repeat-containing protein 35.
WD repeat domain 35 isoform 2.

Cassette

Protein motif
chr3
HIX0200487
HIT000004633
HIT000039654
UBA3
UBA3
Ubiquitin-activating enzyme 3 isoform 2.
NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C).

Cassette

GO
chr5
HIX0200746
HIT000032297
HIT000334521
MAT2B
MAT2B
Methionine adenosyltransferase II, beta isoform 2.
Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Methionine adenosyltransferase 2 beta subunit) (DTDP-4-keto-6-deoxy-D-glucose 4- reductase).

Alternative first exon

Subcellular localization signal
chr10
HIX0201517
HIT000263278
HIT000389762
FGF8
FGF8
Fibroblast growth factor 8 isoform F precursor.
Fibroblast growth factor 8 isoform A precursor.

Cassette

Internal acceptor

Protein motif
chr12
HIX0201913
HIT000053975
HIT000434087
TMPO
TMPO
Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].
Similar to Thymopoietin zeta isoform.

Alternative last exon

GO
Subcellular localization signal
chr17
HIX0202399
HIT000011058
HIT000011116
CCDC47
CCDC47
Similar to Coiled-coil domain-containing protein 47 precursor.
Coiled-coil domain-containing protein 47 precursor.

3'-end AS

Subcellular localization signal
chr19
HIX0202740
HIT000010791
HIT000052428
SLC44A2
SLC44A2
Protein of unknown function DUF580 family protein.
Choline transporter-like protein 2 (Solute carrier family 44 member 2).

Alternative first exon

Protein motif
chr22
HIX0203168
HIT000024628
HIT000424437
LIMK2
LIMK2
LIM domain kinase 2 isoform 2b.
LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

Alternative first exon

Protein motif