HIT000035989_Homo.            1 -M--------------------------------------------VVVAAAPNPADGTP 15
XM_515053_Pan.                  MV--------------------------------------------VVAAAAPNPADGTP
ENSPPYT00000013556_Pongo.       MV--------------------------------------------VVAAAAPSPTDGTP
ENSMMUT00000010080_Macaca.      -M--------------------------------------------VVVAAAPSPADGAP
AF443192_Mus.                   -M--------------------------------------------VVVAAAPSAATAAP
BC079450_Rattus.                -M--------------------------------------------VVVAAAPSAASAAP
ENSCAFT00000018984_Canis.       -P--------------------------------------------APAPPAQSPAAGAP
XM_001916129_Equus.             -M--------------------------------------------VVVAAAQSPAVGGP
XM_001255847_Bos.               -MAQIPLFGAKTIGRRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQ
ENSMODT00000010885_Monodelphis. ----------------------------------------------VVVAAERAPEGGAA
BC152195_Danio.                 -M--------------------------------------------VVVT---AGTGGAH
ENSORLT00000001476_Oryzias.     -M--------------------------------------------VVVA---TGSGGAH
CR656327_Tetraodon.             -M--------------------------------------------VVVT---AGTGGAH
AB236416_Takifugu.              -M--------------------------------------------VVVT---AGTGGAH
                                                                              . .           

HIT000035989_Homo.           16 KVLLLSGQPAS----------AAGAPAGQALPLMVPA---QRGASPEAASGGLPQARKRQ 62
XM_515053_Pan.                  KVLLLSGQPAS----------AAGAPAGQALPLMVPA---QRGASPEAASGGLPQARKRQ
ENSPPYT00000013556_Pongo.       KVLLLPGQPAS----------AAGAPAGQALPLMVQA---QRGASPEAASGGLPQARKRQ
ENSMMUT00000010080_Macaca.      KVLLLSGQPAS----------AAGAPAGQALPLMVPA---QRGASPEAASGGLPQARKRQ
AF443192_Mus.                   KVLLLSGQPAS---------------GGRALPLMVPG---PRAAGSEAS--GTPQARKRQ
BC079450_Rattus.                KVLLLSGQPAS---------------GGRALPLMVPG---PRAAGSEAS--GTPQARKRQ
ENSCAFT00000018984_Canis.       KVLLLSGKPAA--------AAAAGAPAGRALPLMVPG---PRGASPEAPCGGPPQARKRQ
XM_001916129_Equus.             KVLLLSSKPAA--------AAAAGSPAGRALPLMVPG---QQGASPEEASGGPSQARKRQ
XM_001255847_Bos.               NCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPK---VFLASVSGIC----------
ENSMODT00000010885_Monodelphis. PVDALVADLGA----------VEHRVAGRAAALAGRA---SAAAAAAAAAAAVAARAVRQ
BC152195_Danio.                 KVLLISGKQSAS-------TGATQGGYSRSISVMIPN---QASSDSDSTTSG-PPLRKRQ
ENSORLT00000001476_Oryzias.     KVLLISGKQAG--------SGGSQTAFSRPISVVLPS--SQVSSDSDSNSSVGQPVRKRQ
CR656327_Tetraodon.             KVLLISGKQS-----------GSQADFGRPISVVLPSATSQTSSDSDSNSSGRPPIRKRQ
AB236416_Takifugu.              KVLLISGKQSGS-------SGGSQPGFSRPISVVLPSATSHTSSDSDSNSSAGPPVRKRQ
                                         .                 .:              :                

HIT000035989_Homo.           63 RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK 122
XM_515053_Pan.                  RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
ENSPPYT00000013556_Pongo.       RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
ENSMMUT00000010080_Macaca.      RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
AF443192_Mus.                   RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENHKLQLENQLLREK
BC079450_Rattus.                RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLQLENQLLREK
ENSCAFT00000018984_Canis.       RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
XM_001916129_Equus.             RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
XM_001255847_Bos.               --------SNAATLKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK
ENSMODT00000010885_Monodelphis. IILYVAPNE-ALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLIENQLLRER
BC152195_Danio.                 RLTHLSPEEKALRRKLKNRVAAQTARDRKKAKMGELEQQVLELELENQKLHVENRLLRDK
ENSORLT00000001476_Oryzias.     RLTHLSPEEKALRRLVAEKKPP--IDNDNKYNFGXLHLFWVYSVLWNELIHT--------
CR656327_Tetraodon.             RLTHLSPEEKALRRKLKNRVAAQTARDRKKAKMGELEQQVLELELENQKLHIENRLLQEK
AB236416_Takifugu.              RLTHLSPEEKALRRKLKNRVAAQTARDRKKAKMGELEQQVLELEMENQKLHIENRLLQEK
                                        . *    : :: ..    : :* .:. *.   :     *. :          

HIT000035989_Homo.          123 THGLVVENQELRQRLGMDALVAEE--EAE---AKGNEVRPVAGSAESAALRLRAPLQQVQ 177
XM_515053_Pan.                  THGLVVENQELRQRLGMDALVAEE--EAE---AKGNEVRPVAGSAESAALRLRAPLQQVQ
ENSPPYT00000013556_Pongo.       THGLVVENQELRQRLGMDALVAEE--EAE---AKGNEVRPVAGSAESAA-------GAGP
ENSMMUT00000010080_Macaca.      THGLVVENQELRQRLGMDALVAKE--EAE---AKGNGVRPVAGSAESAALRLRAPLQQVQ
AF443192_Mus.                   THGLVVENQELRTRLGMDTLDPDEVPEVE---AKGSGVRLVAGSAESAA-------GAGP
BC079450_Rattus.                THGLVIENQELRTRLGMNALVTEEVSEAE---SKGNGVRLVAGSAESAALRLRAPLQQVQ
ENSCAFT00000018984_Canis.       THGLVVENQELRQRLGMDTLATEE--EAET-QTKGNGVRPVAGSAESAALRLRAPLQQVQ
XM_001916129_Equus.             THGLVVENQELRQRLGMDALGTEE--EAE---TKGNGARPVSGSAESAA-------GAGP
XM_001255847_Bos.               THGLVVENQELRQRLGMDALVTEE--EAE---TKGNGAGLVAGSAESAALRLRAPLQQVQ
ENSMODT00000010885_Monodelphis. THGLVIENQELRQRLGMDALMPEE-EETE---SKVNDVRAVAGSAESAALRLCAPLQAGP
BC152195_Danio.                 TSDLLSENEELRQRLGLDTLETKE--QVQVLESAVSDLGLVTGSSESAA-------GAGP
ENSORLT00000001476_Oryzias.     --------------------------QVQTLSSGGSDAGLGTGSSESAALRLRVPPQQVQ
CR656327_Tetraodon.             TNGLLAENEELRQRLSLDALDSKD--KVQCLLSNGNETGLGVGSSESAALRLRVPPQQVQ
AB236416_Takifugu.              TSGLLAENEELRQRLSLDTIDSKD--EVQCLLSTGKEAGLGVGSSESAALRLRVPPQQVQ
                                                          :.:   :  .      **:****           

HIT000035989_Homo.          178 AQLSPL----------QNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQS-LPA 226
XM_515053_Pan.                  AQLSPL----------QNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQS-LPA
ENSPPYT00000013556_Pongo.       VVTPPEHLLMDSGGIDSSDSESDILLGILDNLDPIMF--FKCPSPEPASLEELSEV-YPE
ENSMMUT00000010080_Macaca.      AQLSPL----------QNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQS-LPA
AF443192_Mus.                   VVTSPEHLPMDSDTVASSDSESDILLGILDKLDPVMF--FKCPSPESASLEELPEV-YPE
BC079450_Rattus.                AQLSPP----------QNIFPWILTLLPLQILSLISFWAFWTSWTLSCFSNVLPQS-LLI
ENSCAFT00000018984_Canis.       AQLSPL----------QSISPWILTALTLQTLSLISCWAFCSTWIQSCSSDVLLQS-LPA
XM_001916129_Equus.             VVTPPEPLPMDSDSVDSSDSESDILLGILFNLDPVMF--FRCPSPESTSLEQLPEV-YPE
XM_001255847_Bos.               AQLSPL----------QNISPWTLMALTLQTLSLTSCWAFCSTWTQSCSSDVLPQS-LPA
ENSMODT00000010885_Monodelphis. AVTLPEHVPVDSDGLDSSDSESDILLGILDNLDPDMF--FRYVTAEG-GLEEPREVGAAQ
BC152195_Danio.                 AVPKSEDFTMDTHSPGPADSESDLLLGILDILDSELF--LKTDLPEAQEPQQELVL-VGG
ENSORLT00000001476_Oryzias.     AQQSLK----------LKTSQWIQIVLTLQTLSLICCWAFWTSLTQSCFSSRAKS-----
CR656327_Tetraodon.             AQQLPK----------LKTSQWIQAVLILQTLSLICFWAFWTSLTQSCSSDLVSRS-A--
AB236416_Takifugu.              AQQLLN----------LKTSQWIQAVLILQTLSLICFWAFWTSLTQSCSSDLVS------
                                .                           *   .      :          .         

HIT000035989_Homo.          227 WRSSQRSTQK-------------------DPVPYQP-----------------------P 244
XM_515053_Pan.                  WRSSQRSTQK-------------------DPVPYQP-----------------------P
ENSPPYT00000013556_Pongo.       GPSSLPASLSLSVGTSSAKLEAINELIRFDHIYTKPLVLEIPSETESQ-ANVVVKIEEAP
ENSMMUT00000010080_Macaca.      WRSSQRSTQK-------------------DPVPYQP-----------------------P
AF443192_Mus.                   GPSSLPASLSLSVGTSSAKLEAINELIRFDHVYTKPLVLEIPSETESQ-TNVVVKIEEAP
BC079450_Rattus.                WRNSQRSTQK-------------------DLVPYQP-----------------------P
ENSCAFT00000018984_Canis.       WSSFQRSTQK-------------------DPVPYRP-----------------------P
XM_001916129_Equus.             GPSSLPASPSPSLGTSSAKLEAINELIRFDHVYTKPLVLEIPSETESQ-ANVVVKIEEAP
XM_001255847_Bos.               WSSSQKWTQK-------------------DPVPYRP-----------------------P
ENSMODT00000010885_Monodelphis. EPSSVPASPSPLVGPPSAKLEAINELIRFDHVYTKPLVLELPSEADGPGGSVVVKIEEVP
BC152195_Danio.                 AGEQVPSSAPAALGPAPVKLEALNELIHFDHIYTKPAEVLVSEESICE----VKAEDSVA
ENSORLT00000001476_Oryzias.     -RPRRSCWSE-------------------GGTQYLP-----------------------P
CR656327_Tetraodon.             -RSRRCSWSE-------------------GGIQYLP-----------------------P
AB236416_Takifugu.              -RSRRCSWSE-------------------GGTQYLP-----------------------P
                                                             .     *                       .

HIT000035989_Homo.          245 FLCQWGRHQ--------------------------------------------------- 253
XM_515053_Pan.                  FLCQWGRHQ---------------------------------------------------
ENSPPYT00000013556_Pongo.       LSPSENDHP--EFIVSVKEEPVE-----DDLVPELGISNLLSSSH-CPKPSSCLLDAYSD
ENSMMUT00000010080_Macaca.      FLCQWGRHQ---------------------------------------------------
AF443192_Mus.                   LSSSEEDHP--EFIVSVKKEPLE-----DDFIPELGISNLLSSSH-CLRPPSCLLDAHSD
BC079450_Rattus.                FLCQWGPHQ---------------------------------------------------
ENSCAFT00000018984_Canis.       LLHHWGRHQ---------------------------------------------------
XM_001916129_Equus.             SSPSEKDHP--ELTVSVKEELVE-----DDFIPELGISDLLSSSH-CLKPSSCLLDAYSD
XM_001255847_Bos.               LLHPWGRHQ---------------------------------------------------
ENSMODT00000010885_Monodelphis. LSPSLKPEPPEPLTVAVKEELLD-----EDLIPELGMENLLCSSH-GLKASPYLLDACSD
BC152195_Danio.                 FSETEEEIQVEDQTVSVKDEPEEVVIPAENQTPDAADDFLSDTSFGGYEKASYLTDAYSD
ENSORLT00000001476_Oryzias.     HLQLWGPHQ---------------------------------------------------
CR656327_Tetraodon.             HLRLWGTHQ---------------------------------------------------
AB236416_Takifugu.              HLRLWGPHQ---------------------------------------------------
                                                                                            

HIT000035989_Homo.          254 --------------------PSWKPLMN----------- 261
XM_515053_Pan.                  --------------------PSWKPLMN-----------
ENSPPYT00000013556_Pongo.       CGYGGSLSPFSDMSSPLGVNHSWEDTFANELFPQLI-SV
ENSMMUT00000010080_Macaca.      --------------------PSWKPLMN-----------
AF443192_Mus.                   CGYEGSPSPFSDMSSPLGTDHSWEDTFANELFPQLI-SV
BC079450_Rattus.                --------------------PSWKPLMNSFVLTMYTPSL
ENSCAFT00000018984_Canis.       --------------------PSWKPLMN-----------
XM_001916129_Equus.             CRYEGSSSPFSDMSSLLGADHSWEDTFANELFPQLI-SV
XM_001255847_Bos.               --------------------PSWKPLMN-----------
ENSMODT00000010885_Monodelphis. SGYEGSPSPFNELSSPLGAGPSWEDTFANELFPQLI-SV
BC152195_Danio.                 SGYERSPSPFSNISSPLCSEGSWDDMFASELFPQLI-SV
ENSORLT00000001476_Oryzias.     --------------------LSWRPLMN-----------
CR656327_Tetraodon.             --------------------LSWRPLMN-----------
AB236416_Takifugu.              --------------------LSWRPLMN-----------
                                                     **   :