HIT000013556_Homo. 1 ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN 49
XM_524625_Pan. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
ENSPPYT00000002021_Pongo. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
XM_001108306_Macaca. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
DQ229108_Mus. ----MDYKSGLIPD-------GNAMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
BC061824_Rattus. ----MDYKSGLIPD-------GNAMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
XM_544488_Canis. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
ENSECAT00000026380_Equus. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
BC112721_Bos. ----MDYKSSLIQD-------GNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
XM_001369455_Monodelphis. ----MDYKSGLIQD-------SNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
BX931246_Gallus. ----MDFQPSILRD-------GSPMESLEKQLLCPICLEMFSKPVVILPCQHNLCRKCAN
BC049414_Danio. MD--IQRTASLLGT-------PDSMEGLEKQLSCPICLDMFTKPVVILPCQHNLCRGCAS
BC075897_Danio. MSVTLDY--CLSRS-------RDTMESLERQLICPICLEIFTKPVVILPCQHNLCRKCAN
ENSORLT00000010271_Oryzias. ----VQRTGSIVRP-------PSPMDSLEKQLSCPICLEMFTKPVVILPCQHNLCRSCAS
CR670382_Tetraodon. MNFALGCKPPSAGSSGPGAPRGTAMENLEKQLVCPVCLEMFSKPVVILPCQHNLCRKCAS
SINFRUT00000155215_Takifugu. ------------------------MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCAN
*:.**:** **:**::*:************** **.
HIT000013556_Homo. 50 DIF-QAANPYWTSRGSSV-SMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ 107
XM_524625_Pan. DIF-QAANPYWTSRGSSV-SMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
ENSPPYT00000002021_Pongo. DIF-QAANPYWTSRGSSV-SMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
XM_001108306_Macaca. DIF-QAANPYWTGRGSSV-SMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
DQ229108_Mus. DIF-QAANPYWTNRGGSV-SMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
BC061824_Rattus. DIF-QAANPYWTNRGGSV-SMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
XM_544488_Canis. DIF-QAANPFWTNRVGSV-SMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
ENSECAT00000026380_Equus. DIF-QAANPYWTNRSGSV-SVSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
BC112721_Bos. DIFQQAANPYWTGRVGSA-AMSGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
XM_001369455_Monodelphis. DVF-QAANPYWSNRGGSI---SGGRFRCPSCRHEVIMDRHGVYGLQRNLLVENIIDIYKQ
BX931246_Gallus. DIF-QAANPYWQSRGSS--IISGARFRCPTCRHEVLLDRHGVYGLQRNLLVENIIDIYKQ
BC049414_Danio. DLY-DSRNPY---------RFSGGVFRCPTCRFEVVLDRHGVHGLQRNLLVENIIDIYKQ
BC075897_Danio. DIF-QASNPYLPTRGGSS-LGSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDMYKQ
ENSORLT00000010271_Oryzias. DLY-DSRNPY---------RYSGGVFRCPTCRFEVVLDRHGVHGLQRNLLVENIIDIYKQ
CR670382_Tetraodon. DIF-QEANHLGHSRGSSAAVLSGSRFRCPSCRHEVVLDRHGIYGLQRNLLVENIIDVYRQ
SINFRUT00000155215_Takifugu. DIF-QASNPYLPTRAGS--LTSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDMFKQ
*:: : * **. ****:**.**::****::*************:::*
HIT000013556_Homo. 108 ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACE 155
XM_524625_Pan. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACE
ENSPPYT00000002021_Pongo. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACE
XM_001108306_Macaca. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGVHKACE
DQ229108_Mus. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSLCKVFGAHQACE
BC061824_Rattus. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSLCKVFGAHQACE
XM_544488_Canis. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEMPTCSMCKVFGAHKACE
ENSECAT00000026380_Equus. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGAHQACE
BC112721_Bos. ECS---------S-RPL--QKGSHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGAHKACE
XM_001369455_Monodelphis. ECS---------S-RPL--QKGNHPMCKEHEDEKINIYCLTCEVPTCSMCKVFGAHKACE
BX931246_Gallus. EFS---------S-RPL--KKGEHPMCKEHEDERINIYCVTCEVPTCSMCKVFGAHKDCE
BC049414_Danio. QQEGGGGGGGSTTESPIKPKSSKELMCQEHEDEKINIYCVTHQTPTCSMCKVFGQHKDCE
BC075897_Danio. ESS---------SSKPEPQVKEEVLMCEEHQDERINIYCVTCSVPTCSLCKVFGSHQTCE
ENSORLT00000010271_Oryzias. QQEGRNSG---DTETSLKTKESKEPMCQEHDDERINIYCVTCQVPTCSMCKVFGQHKDCE
CR670382_Tetraodon. QEA--------ARLVAMKPKQPQQLLCEDHEDEKINIYCLSCQTPTCSMCKVFGKHKDCD
SINFRUT00000155215_Takifugu. ESS---------SGKPVEERKEQMPMCDVHEGEKINIYCITHAVPTCSMCKIFGAHKDCE
: . . . :*. *:.*:*****:: ****:**:** *: *:
HIT000013556_Homo. 156 VAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDT 215
XM_524625_Pan. VAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDT
ENSPPYT00000002021_Pongo. VAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSCRVTKENSHQVKEELSQKFDT
XM_001108306_Macaca. VAPLQSVFQGQKIELNNCISMLVAGNDRVQTIITQLEDSCRVTKENSHQVKEELSQKFDT
DQ229108_Mus. VAPLQSIFQGQKTELSNCISMLVAGNDRVQTIISQLVDSCRVTKENSHQVKEELSQKFDT
BC061824_Rattus. VAPLQSIFQGQKTELSNCISMLVAGNDRVQTIISQLEDSCRVTKENSHQVKEELSHKFDA
XM_544488_Canis. VAPLQSVFQGQKTELSNCISMLVAGNDRMQTIITQLEDSCRVTKENSHHVKEELSQKFDV
ENSECAT00000026380_Equus. VAPLQSVFQGQKTELSNCVSMLVAGNDRVQTIITQLEDSCRVTKENSRQVKEELSRKFDA
BC112721_Bos. VAPLQSVFQGQKTELSNCISMLVAGNDRVQTIITQLEDSCRVTKENSHQVKEELSQKFDT
XM_001369455_Monodelphis. VAPLQNVFQGQKTELSNCISMLVAGNDRVQTIITQLEDSCRVTKENSHQVKEELSEKFDV
BX931246_Gallus. VAPLQSIFQGQKSELNNCISMLVAGNDRIQTIISQLEDSCRSTEENSEAAKQELCARFDA
BC049414_Danio. VSPLASVYQAQKGELSNAIDALVAGNGRLQALLNQMEEACTAVQDNAQRAKQKFGECFDS
BC075897_Danio. VAPLKSVYESQKTELSDGVGLLVGNNDRIQGIISQLEETCRSVEENGRRQKSRVCEWFDR
ENSORLT00000010271_Oryzias. VAPLETVYQTQKGELSNAIDTLVASNARLQALLNQMDDACRAVQDNAQTAKQGLAERFDL
CR670382_Tetraodon. GAPLDNVYFRTKTELSDGIAVLVAKHDHVQEHISQMEDMCRTIEENGKQQQEQLAGRFYR
SINFRUT00000155215_Takifugu. VSPITSIYQTKKMELSDGIAMMVGNNDRMQGIISQLEETCRAIEENGRRQKTMVCEKFDQ
:*: .:: * **.: : :*. : ::* :.*: : ::*.. : . *
HIT000013556_Homo. 216 LYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATF 275
XM_524625_Pan. LYAILDEKKSELLQRITQEQEEKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATF
ENSPPYT00000002021_Pongo. LYAILDEKKSELLQRITQEQEEKLSFIEALIQQYQEQLDKSTKLMETAIQSLDEPGGATF
XM_001108306_Macaca. LYAILDEKKSELLQRITQEQEEKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATF
DQ229108_Mus. LYAILDEKKSELLQRITQEQEEKLGFIEALILQYREQLEKSTKLVETAIQSLDEPGGATF
BC061824_Rattus. LYAILDEKKSELLQRITQEQEEKLDFIEALILQYREQLEKSTKLVETAIQSLDEPGGATF
XM_544488_Canis. LYAILDEKKSELLQRITREQEDKLSFIEGLIQQYREQLDKSTKLVETAIQSLDEPGGAIF
ENSECAT00000026380_Equus. LYAILDEKKSELLQRITQEQEEKLSFIEALIQQYREQLDKSTKLVETAIQSLDEPGGAIF
BC112721_Bos. LYAILDEKKSELLQRITREQEEKLGFLEALIQQYREQLDKSTKLVETAIQSLDEPGGAIF
XM_001369455_Monodelphis. LYAILDEKKSELLQRITREQEEKISFIEALIQQYREQLEKATKLVETAIQSMDEPGGAAF
BX931246_Gallus. FSALLEEKKTELLGRITREQEDKTSFVQGLIHKYKEQLEKSSRLVETAIQAMEETGGAAF
BC049414_Danio. LYAALEERKNALLERIGKEQDEKVGALRSLARRYGDRLQAATELTDMAVQALEQSGAAEF
BC075897_Danio. LYALLEERRGDLTLKITAEQQEKLDYISGLQRKYREHLDNSAKLVETGIQTMEESEMAIF
ENSORLT00000010271_Oryzias. LYAILEERKAILLEQIGKEQDEKVAALRALAQRYGERLQASTELTDSAVRALEQNGAAEF
CR670382_Tetraodon. LVVTLEERKQELVGLISKEQDHKLKRARSLLRRYREQLEAAVALVESAIRSMEEPHMSAF
SINFRUT00000155215_Takifugu. LYSVLEEKKREMSQKVTDEQEEKLSYIRSLTRKYGDHLEQSCKVVEMGIQNMEEPEMALF
: *:*:: : : **:.* .* :* ::*: : : : .:: ::: : *
HIT000013556_Homo. 276 -----------------LLTAKQLIKSIVEASKGC-QLGKTEQGFENMDFFTLDLEHIAD 317
XM_524625_Pan. -----------------LLTAKQLIKSIVEASKGC-QLGKTEQGFENMDFFTLDLEHIAD
ENSPPYT00000002021_Pongo. -----------------LLTAKQLIKSIVEASKGC-QLGKTEQGFENMDCFTLDLEHIAD
XM_001108306_Macaca. -----------------LLTAKQLIKSIVEASKGC-QLGKTEQGFENMDFFTLNLEHIAD
DQ229108_Mus. -----------------LSSAKQLIKSNVEASKGC-QLGKTEQGFENMDYFTLDLEHIAE
BC061824_Rattus. -----------------LLSAKPLIKSIVEASKGC-QLGKTEQGFENMDYFTLNLEHIAE
XM_544488_Canis. -----------------LLSAKQLIKSIVEASKGC-QLGKTEQGFENMDYFTLDLEHIAN
ENSECAT00000026380_Equus. -----------------LLSAKKLIKSIVEASKGC-QLGKTEQGFENMDYFTLDLEHIAD
BC112721_Bos. -----------------LLSAKQLIRSIVEASKGC-QLGKIEQGFENMDYFTLDLEHVAD
XM_001369455_Monodelphis. -----------------LMNAKPLIKAIVEASKGC-HLGKTEQGFENMDYFTLDLEHIAD
BX931246_Gallus. -----------------LMNAKQLIKTIVEASKGG-RLEKIEQGYENMDAFTVSLEHLAD
BC049414_Danio. -----------------LQASKNLISQTKDAAKSSLAEERPEPGFERMDHFTLDTEQVET
BC075897_Danio. -----------------LQNTKPLLQQIAESRNVS-HLEKVERGYENMDHFSANFQSERR
ENSORLT00000010271_Oryzias. -----------------LLLSKGLITQTKDAAKSSLGEERPEPGFEKMDHFTLSTEHVET
CR670382_Tetraodon. -----------------IQSANVILERMAAASRTS-STERPELGYENMNHFTVDTEEAAA
SINFRUT00000155215_Takifugu. LQECRNSMKNVSYFFCLLQNTKPLLKKITDATSTA-HLDKVERGYENMDHFHVEFKKVGQ
: :: :: : : * *:*.*: * . :
HIT000013556_Homo. 318 ALRAIDFGTDEEEEEFI---EEEDQEEEESTEGK-------------------------- 348
XM_524625_Pan. ALRAIDFGTDEEEEEFI---EEEDQEEEESTEGK--------------------------
ENSPPYT00000002021_Pongo. ALRAIDFGTDEEEEEFI---EEEDQEEEDSTEGK--------------------------
XM_001108306_Macaca. ALRAIDFGTDEEEEEFI---EEEDQEEEGSTEGK--------------------------
DQ229108_Mus. ALRAIDFGTDEEEEEFT--EEEADEEEGVTTEGH--------------------------
BC061824_Rattus. ALRAIDFGTD-EEEEFTEEEEEEDQEEGVSTEGH--------------------------
XM_544488_Canis. TLRAIDFGTDEEEEEFI--EEEEDQEEEESTERK--------------------------
ENSECAT00000026380_Equus. TLRAIDFGTDEEEEEFF---EEEDQEEEESTEGK--------------------------
BC112721_Bos. TLRTIDFGTDEEEEEFI--QEEEDHEEEESTEGK--------------------------
XM_001369455_Monodelphis. TLRAIDFGSDEEEEEFIEAEGDEDEQEEEDLSGG--------------------------
BX931246_Gallus. AVRALDFEPDEEDEFYEEVEEDTGDTEPESVVAA--------------------------
BC049414_Danio. LLSKMDFGGEDDEEFEDAEDQEEE------------------------------------
BC075897_Danio. AILSIDFIKDGDDNDEDEDDDEEITVNPEASSGAAPAPVQQRQTPVPNPSPMAADSVQMS
ENSORLT00000010271_Oryzias. LLAKMDFGVADDEDFEDAEEEEDSGGVKLNHE----------------------------
CR670382_Tetraodon. ALQSLHFCSGVEEDEE-AEEDSEVNVPSSSTVGQ--------------------------
SINFRUT00000155215_Takifugu. ALRSID------------------------------------------------------
: :.
HIT000013556_Homo. 349 ----EEGHQ--------------------------------------------------- 353
XM_524625_Pan. ----EEGHQ---------------------------------------------------
ENSPPYT00000002021_Pongo. ----EEGHQ---------------------------------------------------
XM_001108306_Macaca. ----EEGHQ---------------------------------------------------
DQ229108_Mus. ----Q-------------------------------------------------------
BC061824_Rattus. ----Q-------------------------------------------------------
XM_544488_Canis. ----EEGHQ---------------------------------------------------
ENSECAT00000026380_Equus. ----EEGRK---------------------------------------------------
BC112721_Bos. ----EEGHQ---------------------------------------------------
XM_001369455_Monodelphis. ----EDGRTTGTGPRVVHTAVQGRSRRSLQPVPLHLTSPTPPTHTPPRGSLHTTHQLQRF
BX931246_Gallus. ----PQ------------------------------------------------------
BC049414_Danio. ------------------------------------------------------------
BC075897_Danio. LKPSQSANTNPTENTPIVTPTPDSTHIPSADAQAQVTSGPGQTSDDGQRHVFSFSWLNMP
ENSORLT00000010271_Oryzias. ------------------------------------------------------------
CR670382_Tetraodon. ----QSFLAPPLNSSSVFTVVNKSKYTK--------------------------------
SINFRUT00000155215_Takifugu. ------------------------------------------------------------
HIT000013556_Homo. ------------------
XM_524625_Pan. ------------------
ENSPPYT00000002021_Pongo. ------------------
XM_001108306_Macaca. ------------------
DQ229108_Mus. ------------------
BC061824_Rattus. ------------------
XM_544488_Canis. ------------------
ENSECAT00000026380_Equus. ------------------
BC112721_Bos. ------------------
XM_001369455_Monodelphis. SRALAVRRKSAVSPGRGR
BX931246_Gallus. ------------------
BC049414_Danio. ------------------
BC075897_Danio. K-----------------
ENSORLT00000010271_Oryzias. ------------------
CR670382_Tetraodon. ------------------
SINFRUT00000155215_Takifugu. ------------------
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Amino acid abbreviation