Human transcript (Homo sapiens)
flag HIT000058537 (AB017919) PADI4 663 aa
Protein-arginine deiminase type-4; EC=3.5.3.15; Protein-arginine deiminase type IV; Peptidylarginine deiminase IV; HL-60 PAD;
popupCategory I: Identical to known human protein Q9UM07
alignment locusmaps

arrow_ot Cross-species mapping
Chimpanzee genome
(Pan troglodytes)		 n/a
Identity / Coverage (amino acid)*: 88.9% / 100.0%
dN/dS in conserved ORF (%length): 0.430 in 47.1% (≤ 50%)
Window analysis of dN/dS**: No-selection-found
Orangutan genome
(Pongo pygmaeus)		 n/a
Identity / Coverage (amino acid)*: 88.8% / 100.0%
dN/dS in conserved ORF (%length): 0.274 in 17.0% (≤ 50%)
Window analysis of dN/dS**: No-selection-found
Rhesus monkey genome
(Macaca mulatta)		 n/a
Identity / Coverage (amino acid)*: 83.9% / 100.0%
dN/dS in conserved ORF (%length): 0.374 in 34.4% (≤ 50%)
Window analysis of dN/dS**: No-selection-found
* Calculated by FASTY alignment, overriding internal stop codon or frameshift in the primates genome.
** 20-codon with 1-codon step. Fisher's exact test (P < 0.01).

arrow_dl Data download
Sequence (fasta) Transcript, Protein

arrow_go Gene ontology (GO)
Molecular function protein-arginine deiminase activity GO:0004668
calcium ion binding GO:0005509
Biological process protein modification process GO:0006464
peptidyl-citrulline biosynthetic process from peptidyl-arginine GO:0018101
Cellular component cytoplasm GO:0005737

arrow_ip InterPro
Accession number Short name Sequence region (aa)
IPR004303 Protein-arginine deiminase 2-661
IPR008972 Cupredoxin 4-112
IPR013530 Protein-arginine deiminase, C-terminal 278-663
IPR013732 Protein-arginine deiminase (PAD) N-terminal 1-111
IPR013733 Protein-arginine deiminase (PAD) central region 113-273, 113-293
IPR016296 Protein-arginine deiminase, subgroup 1-663